Macrodystrophia Lipomatosa of the Finger: A Case Report.

INTRODUCTION: Macrodystrophia lipomatosa is a rare benign condition characterized by a progressive persistent proliferation of the mesenchymal components and elements, with a disproportionate increase in fibro-adipose tissue. It causes a debilitating functional and psychological effect on the patient and his family. CASE PRESENTATION: A 25-years-old male patient presented complaining of left middle finger swelling which was painless and progressive in size with no restriction of range of motion. Plain X-ray films of the left hand showed a heterogeneous lobulated soft tissue mass on the volar aspect of the middle finger which was confirmed by MRI scan. Surgery was performed by doing a left middle finger soft tissue excision and diagnosis of Macrodystrophia lipomatosa was confirmed by the histopathology report. Patient was on regular follow up in the clinic with no tumour recurrence and an excellent cosmetic as well as functional result with full finger joints range of motion. CONCLUSION: Macrodystrophia lipomatosa should be suspected with this kind of presentations. Combination of the clinical history and examination with the aid of radiological assays aided in the diagnosis of this extremely rare case and led to the appropriate management by excising this mass and restoring the normal function of the patient's hand.

White mineral trioxide aggregate mixed with calcium chloride dihydrate: chemical analysis and biological properties

OBJECTIVES: This study aimed to evaluate the chemical and biological properties of fast-set white mineral trioxide aggregate (FS WMTA), which was WMTA combined with calcium chloride dihydrate (CaCl₂·2H₂O), compared to that of WMTA. MATERIALS AND METHODS: Surface morphology, elemental, and phase analysis were examined using scanning electron microscope (SEM), energy dispersive X-ray microanalysis (EDX), and X-ray diffraction (XRD), respectively. The cytotoxicity and cell attachment properties were evaluated on human periodontal ligament fibroblasts (HPLFs) using methyl-thiazol-diphenyltetrazolium (MTT) assay and under SEM after 24 and 72 hours, respectively. RESULTS: Results showed that the addition of CaCl₂·2H₂O to WMTA affected the surface morphology and chemical composition. Although FS WMTA exhibited a non-cytotoxic profile, the cell viability values of this combination were lesser than WMTA, and the difference was significant in 7 out of 10 concentrations at the 2 time intervals (p < 0.05). HPLFs adhered over the surface of WMTA and at the interface, after 24 hours of incubation. After 72 hours, there were increased numbers of HPLFs with prominent cytoplasmic processes. Similar findings were observed with FS WMTA, but the cells were not as confluent as with WMTA. CONCLUSIONS: The addition of CaCl₂·2H₂O to WMTA affected its chemical properties. The favorable biological profile of FS WMTA towards HPLFs may have a potential impact on its clinical application for repair of perforation defects.

Nano-computed tomography: current and future perspectives

No abstract available.

Cytotoxicity of Fast-set Conventional and Resin-modified Glass Ionomer Cement Polymerized at Different Times on SHED.

OBJECTIVES: To compare the cytotoxicity of conventional GIC and Resin Modified GIC (RMGIC) polymerized at 2 different times on stem cells from human exfoliated deciduous teeth (SHED). STUDY DESIGN: The conventional GIC (Fuji IX GP Extra) and RMGIC (Fuji II LC) were mixed and incubated in a prepared Dublecco's Modified Eagle Medium (DMEM) for seven days. After seeding the characterized SHED for 24 hrs, six replicates of seven serially diluted extracts of each group were added and incubated for 72 hrs. MTT test was used for cytotoxicity evaluation and the data were analysed using Kruskal-Wallis followed by Mann-Whitney test, with the statistical significance set at P<0.05. RESULTS: The half maximal inhibitory concentration (IC50) was found at 45.0 mg/ml, 45.0 mg/ml and 31.25 mg/ml for Fuji IX, Fuji II LC (40s) and Fuji II LC (20s), respectively. Significantly different cytotoxic effects were found between Fuji II LC polymerized at 20 secs and 40 secs, and between Fuji IX and Fuji II LC (20s) (P<0.05), and these were observed in all concentrations except for 50 mg/ml. CONCLUSIONS: RMGIC polymerized at 20 secs exhibited the least favorable cell viability among all groups. Nevertheless, the cell viability was comparable to conventional GICs when the manufacturer's recommended time was doubled (40 secs).

A survey on light intensity outputs of QTH, cabled and cordless LED light curing units

Light intensity output is one of the determinants for adequate curing of visible light-cured materials. The aim of this survey was to evaluate the light intensity outputs (LIOs) of light curing units (LCUs) in dental clinics of Hospital Universiti Sains Malaysia (HUSM) and School of Dental Sciences, Universiti Sains Malaysia (USM). The respective LIOs of all functioning Quartz Tungsten Halogen (QTH) and Light Emitting Diode (LED) LCUs were tested using two light radiometers. For cordless LED LCUs, the testing procedure was done in situ and after being fully charged. Statistical analysis using Kruskal Wallis and Wilcoxon signed ranks tests were performed to compare the LIOs between groups and between the LIOs of in situ and post-charged cordless LED LCUs, respectively. The level of significance was set at 0.05 (p<0.05). The results revealed that 72.72%, 42.47% and 92% of QTH, cabled LED and cordless LED LCUs exhibited acceptable LIOs, respectively. Data analysis using Kruskal Wallis test showed a statistically significant difference between groups (p<0.05). The intergroup comparisons using multiple Mann Whitney test with Bonferroni correction revealed a significant difference between the LIOs of cordless LED and both QTH and cabled LED (p<0.017). The difference between the LIOs of in situ and post charged cordless LED LCUs was also significant (p<0.05). In conclusion, both QTH and cordless LED LCUs performed better in term of LIOs than cabled LED LCUs. Periodic testing of LCUs is essential to ensure optimal performance.

Management of a maxillary first molar tooth with unusual mesiobuccal root anatomy

Sufficient knowledge on the root and root canal anatomy is essential for practicing root canal treatment. The mesiobuccal roots of maxillary molar teeth present an endodontic challenge due to their wide variability and complexity of their internal morphological landmarks. A review on the literature indicates that the prevalence of a third mesiobuccal root canal in the mesiobuccal root of maxillary molar teeth may reach 9%, and the root canal configuration usually is type XV (3-2). These reported data reveal the importance of absolute awareness for this anatomical aberration that requires special attention from dental practitioners while commencing root canal treatment in maxillary molar teeth. Hence, this article aims to report and describe the management of a maxillary first molar tooth with three mesiobuccal root canals, but with an unusual configuration.