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Khirurgiia (Mosk) ; (11): 5-13, 2020.
Artigo em Russo | MEDLINE | ID: mdl-33210501

RESUMO

OBJECTIVE: To improve the outcomes in children with hepatoblastoma. MATERIAL AND METHODS: There were 160 children with focal liver lesions who underwent surgery at the department of liver transplantation in 2008-2019. Patients with malignant tumors made up 77% (n=123). Hepatoblastoma (HB) prevailed (86%, n=106). Liver transplantation was performed in 19 (18%) patients with HB. Median follow-up after transplantation was 24.3 months by December 2019. Follow-up period did not exceed 4 years in more than 2/3 of patients. RESULTS: Overall and disease-free 10-year survival was 87.1% and 82.7%, respectively. Similar values were observed after resections (91.1% and 86.6%). At the same time, actuarial 4-year survival after liver transplantation for HB was 68%. CONCLUSION: Improvement of treatment outcomes may be achieved through multidisciplinary interaction ensuring timely drug therapy and liver transplantation.


Assuntos
Hepatoblastoma , Neoplasias Hepáticas , Transplante de Fígado , Criança , Terapia Combinada , Hepatectomia , Hepatoblastoma/cirurgia , Humanos , Lactente , Neoplasias Hepáticas/cirurgia , Estudos Retrospectivos , Resultado do Tratamento
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