Depression, sexual function and sexual quality of life in women with polycystic ovary syndrome (PCOS) and healthy subjects.

BACKGROUND: Women with polycystic ovary syndrome (PCOS) suffer from a wide range of psychological problems. The goal of this study is to assess depression, sexual dysfunction and sexual quality of life in women with PCO compared with healthy subjects. METHODS: One hundred and six PCO cases and 106 healthy subjects enrolled. They were asked to fill out valid and reliable Persian versions of BDI (Beck depression inventory), FSFIS (Female Sexual Function Index), and sexual quality of life-Female (SQOL-F) questionnaires. RESULTS: One hundred and six PCO cases and 106 healthy subjects enrolled. Mean BDI was significantly higher while FSFI and its subscales as well as SQOL-F were significantly lower in PCO group than controls. There were significant negative correlation between FSFO and BDI (r=-0.43, p < 0.001) and also positive correlation between FSFI and SQOL-F (r = 0.438, p < 0.001) in whole population of the study. In PCO group, 77 (72.6%) had FSFI less than 26.55 and 29 (27.4%) had score more than 26.55. mean BDI was significantly higher in the group with FSFI < = 26.55 than the other group (33 ± 14.4 vs. 12 ± 11.6, p < 0.001) while SLQL-F was significantly lower in the first group (57 ± 16 vs. 74.9 ± 17.6, p < 0.001). Linear regression analysis by considering SQOL-F as dependent and FSFI, age and BDI as independent variables showed that BDI and FSFI are independent predictors. CONCLUSION: Women with PCO, suffer more from depression and sexual dysfunction than healthy subjects.

Comparison of Vitamin D Levels in Fertile and Infertile Men.

Background: Vitamin D is known for its role in calcium metabolism and it has been also shown to be involved in fertility. Previous studies reported an association between the level of vitamin D and semen parameters. There are little studies regrading to this issue in Iranian men. So, we designed this study to assess vitamin D level in Iranian fertile and infertile men. Method: A total of 207 male subjects (112 fertile and 95 infertile) were enrolled in this study. Vitamin D level and semen parameters were compared between the two groups. Results: Mean age, duration of marriage and body mass index (BMI) were not significantly different between the two groups. Frequency of varicocele and previous opioid consumption were significantly higher in the infertile group than the fertile one. Sixty-six (71%) individuals in the infertile group and 61 (55%) in the fertile group had vitamin D levels < 20 (p=0.02). Conclusion: Vitamin D deficiency (< 20) was significantly higher in infertile men.