[Tansitional vesical cell carcinoma metastatizing to the sphenoid sinus]. / Metástasis esfenoidal de un carcinoma de células trancisionales de la vejiga.

Secundary tumors of the paranasal sinus are very uncommon with only one hundred cases reported in the literature up to 2001. The commonest site of the primary tumor is the kidney. The maxillary sinus is most often involved. The Sphenoid sinus is the rarest site. We report a rare case of metastasis to the sphenoid sinces from a transitional cell bladder tumor in a 69-year-old man who died after treatment with chemotherapy and we also review the liteature.

[Quality of life in patients treated for early laryngeal cancer, in healthy people and in those with other associated pathologies]. / Calidad de vida en pacientes tratados por un cáncer de laringe inicial y en personas sanas y con otras patologías.

Nowadays there are different non aggressive treatment options for early laryngeal cancer. However, they are not free of undesirable effects. We have studied this patients' quality of life, by comparing it with that obtained from healthy population and other illness groups (post-AMI patients, Chronic Kidney patients). We have studied 62 T1-T2NoMo laryngeal carcinoma diagnosed at the "Virgen de la Victoria" clinical hospital from Malaga, Spain, between 1990 and 1998. We used the Quality of Life in Málaga (QLM), general QL questionnaire which was developed and validated at the Department of Preventive Medicine of the University of Málaga, Spain. The results were compared with those obtained from ramdom samples in healthy population from Málaga and from various pathology groups. The global QOL of our patients treated for an early glottic cancer (Index Quality of life 29.4%) was better than almost all the other ones.

[Quality of life in patients treated for head and neck cancer]. / Calidad de vida en pacientes tratados por un cáncer de cabeza y cuello.

In this paper we have studied the quality of life of patients that underwent treatment for an early laryngeal carcinoma in comparison to others with an advanced head and neck cancer. We have studied 62 patients (T1N0M0, T2N0M0) with laryngeal carcinoma diagnosed between 1990 and 1998. We have applied the European EORTC QOL C-30 questionnaire, and more specifically its head and neck module (H&N 35). The results were compared with a heterogeneous group of 48 patients with different degrees of head and neck cancers. The quality of life of our patients who were treated for an early glottic cancer was better in many functional scales of the EORTC and in many specific symptom scales of the H&N 35, but not in global cancer symptoms.

Metástasis fronto-etmoidal de adenocarcinoma prostático. Presentación de un caso clínico y revisión de la literatura / Fronto-ethmoid metastases of prostatic carcinoma. Report of one case and review of the literature

Los tumores metastásicos en fosas y senos paranasales son enormemente raros, existiendo menos de cien casos descritos en las distintas revisiones bibliográficas. Los tumores primarios de origen de estas metástasis son, en orden de frecuencia, el hipernefroma, el cáncer de pulmón y el cáncer de mama. El adenocarcinoma prostático como productor de metástasis en senos paranasales es excepcional, existiendo únicamente diez casos descritos en la literatura, siendo la localización más común el seno esfenoidal y el maxilar. Presentamos el caso clínico de un paciente varón de 72 años de edad, que debuta con sintomatología de sinusitis aguda frontoetmoidal derecha y celulitis orbitaria ipsilateral. El estudio radiológico mediante TAC demuestra la existencia de una ocupación masiva de todos los senos paranasales derechos, así como una colección subdural frontal, compatible con absceso o empiema subdural. En el acto quirúrgico se comprueba la existencia de una masa tumoral a nivel frontoetmoidal derecho, como proceso de ase, confirmándose posteriormente el diagnóstico histopatológico de adenocarcinoma prostático, con positividad inmunohistoquímica para el Antígeno Prostático Específico (PSA) (AU)

Prostatic metastases in the nose and paranasal sinuses are rare. Less than 100 cases have been reported in the literature. Kidney are the commonest site of primary tumour, followed by lung and breast. Only 10 cases have previously been reported in the world literature. Prostatic metastases have been mainly reported in the sphenoid sinus. This paper reports one case of metastases of prostatic carcinoma in the fronto-ethmoid sinus in a 72 years old male. The clinical picture includes acute fronto-ethmoid right sinusitis, severe exophthalmos and chemosis. The CT scan showed extensive soft tissue filling the maxillary, ethmoid cells, sphenoid and frontal right sinuses, with subdural abscess. Biopsies from the fronto-ethmoid mass showed infiltration by adenocarcinoma with positive immunostaining for prostatic specific antigen. We also review the literature about metastases involving the nose and paranasal sinuses (AU)

[Small-cell carcinoma of the larynx]. / Carcinoma de células pequeñas de laringe.

Primary small-cell (also known as oat-cell) neuroendocrine carcinoma of the larynx is an infrequent tumor. We report a case of epiglottic oat-cell carcinoma in a 57-year-old man. Its association with other malignant neoplasms and aggressive behavior in spite of treatment are discussed.