Neonatal thoracoabdominal aortic thrombosis associated with the umbilical artery catheter: successful management by transaortic thrombectomy.

The case of a newborn infant who underwent a successful aortoiliac thrombectomy for thoracoabdominal aortic thrombosis induced by an umbilical artery catheter is presented. The case is notable both for the extent of the thrombotic process and the renal and cardiac failure noted initially. Only eight other attempts at neonatal aortic thrombectomy associated with umbilical artery catheters have been reported in the English language literature. Our experience, in addition to that in the literature, suggests that aggressive treatment should be considered in neonates with this severe complication.

Partial trisomy 11p with interatrial septal aneurysm. Case report and literature review.

A newborn female infant presented with hypotonia, joint hyperextensibility, cardiac murmur, macroglossia, and hepatosplenomegaly. Karyotype of the child revealed partial trisomy of chromosome 11p derived from a paternal balanced translocation. Echocardiogram obtained in the newborn period suggested interatrial aneurysm, which was confirmed on post-mortem examination. Interatrial septal aneurysm is a rare abnormality not previously described in partial trisomy 11p.