1.
J Am Chem Soc
; 132(5): 1482-3, 2010 Feb 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20078122
RESUMO
A direct ruthenium-catalyzed radical chloroalkylation of N-acyl oxazolidinones capitalizing on valence tautomerism of titanium enolates has been developed. The chloroalkylation method served as the centerpiece in the enantioselective total synthesis of trichloroleucine-derived marine natural product neodysidenin.