[Long-term portal hypertension in the rat by means of triple stenotic ligation of the portal vein]. / Hipertensión portal a largo plazo en la rata por triple ligadura estenosante de la vena porta.

OBJECTIVE: To improve the technique of stenosing ligation of the portal vein, frequently used to obtain a prehepatic portal hypertension model in the rat, by increase the initial resistance to the blood flow. METHODS: In this experimental work portal stenosis by three equidistant stenosing ligatures which are fixed in a plastic guide is proposed as an alternative technique. RESULTS: Triple stenosing ligation of the portal vein does not produce mortality and causes splenomegaly as well as a larger degree of collateral venous circulation, particularly of splenorenal type, in relation to rats with a simple stenosing ligation. CONCLUSION: Increase of the stenosed tract length of the portal vein in the rats with triple ligation increases the initial resistance to the portal flow and then the posterior evolution would be impaired and this mechanism could be involved in a larger degree of collateral venous circulation.

Hipertensión portal a largo plazo en la rata por triple ligadura estenosante de la vena porta / Long-term portal hypertension in the rat by means of triple stenotic ligation of the portal vein

Objetivo: Mejorar la técnica de la ligadura estenosante portal, habitualmente utilizada como modelo experimental de hipertensión portal prehepática en la rata, aumentando la resistencia inicial al flujo sanguíneo. Método: Para ello se propone como alternativa la estenosis portal por tres ligaduras estenosantes equidistantes que se mantienen en posición mediante su fijación a una guía plástica. Resultados: La triple ligadura estenosante de la vena porta no produce mortalidad en la rata y a los 45 días del postoperatorio causa esplenomegalia y mayor desarrollo de circulación colateral, en particular de tipo esplenorenal, respecto de la ligadura simple. Conclusión: El aumento de la longitud del trayecto portal estenosado en las ratas con triple ligadura podría aumentar la resistencia inicial al flujo y así agravar la evolución posterior, causando mayor desarrollo de circulación colateral (AU)

[Bochdalek's hernia in an adult with stomach volvulus and extrapulmonary sequestration]. / Hernia de Bochdalek del adulto con volvulación gástrica y secuestro extrapulmonar.

We report a case of Bochdalek's hernia with volvulus of the stomach and extrapulmonary sequestration in an adult. A 27-year-old woman presented acute respiratory failure, pain in the left side of the chest and recurrent vomiting of sudden onset. Upon examination there was pain in the left hypochondrium that was not tolerated in decubitus position. A chest film showed an "arch" at the base on the left side and an upper gastrointestinal series revealed volvulus of the stomach. After a left thoracotomy, the stomach, spleen and greater omentum were found displaced into the thoracic cavity. After the viscera were confined to the abdomen, the hernia was repaired and the pulmonary sequestration was removed. Two years later, the patient was asymptomatic and a chest film was normal.