Orthodontic treatment in a patient with Moebius syndrome: A case report.

Moebius syndrome (MBS) is a congenital neurologic disorder that causes cranio-facial abnormalities. It involves paralysis of the VI and VII cranial nerves and causes bilateral or unilateral facial paralysis, eye movement disorder, and deformation of the upper and lower limbs. The orofacial dysfunctions include microstomia, micrognathia, hypotonic mimetic and lip muscles, dental enamel hypoplasia, tongue deformity, open bite or deep overbite, maxillary hypoplasia, high arched palate, mandibular hyperplasia or features indicating mandibular hypoplasia. This case report presents a 7-year-old male patient who was diagnosed with MBS at the age 2 years. The patient displayed typical clinical symptoms and was diagnosed with Class II malocclusion with a large overjet/overbite, tongue deformity and motion limitation, and lip closure incompetency. Treatment was initiated using a removable appliance for left scissor bite correction. After permanent tooth eruption, fixed appliance treatment was performed for correction of the arch width discrepancy and deep overbite. A self-ligation system and wide-width arch form wire were used during the treatment to expand the arch width. After 30 months of phase II treatment, the alignment of the dental arch and stable molar occlusion was achieved. Function and occlusion remained stable with a Class I canine and molar relationship, and a normal overjet/overbite was maintained after 9.4 years of retainer use. In MBS patients, it is important to achieve an accurate early diagnosis, and implement a multidisciplinary treatment approach and long-term retention and follow-up.

Three-dimensional morphologic evaluation of the changes in the pharyngeal airway and hyoid bone after bimaxillary surgery in patients with skeletal Class III malocclusion with facial asymmetry: A preliminary study.

INTRODUCTION: The study aimed to evaluate the morphologic changes in the pharyngeal airway after bimaxillary surgery in skeletal Class III malocclusion patients with or without asymmetry. We also analyzed the correlation between positional changes in the menton, hyoid bone, and changes in the dimensions of the pharyngeal airway. METHODS: We included 32 patients with skeletal Class III malocclusion who underwent bimaxillary surgery. There were 16 subjects in the symmetry group (10 male, 6 female; mean age, 22.44 ± 5.14 years), and 16 in the asymmetry group (10 male, 6 female; mean age, 21.38 ± 4.62 years). Preoperative and postoperative (2 months after surgery) cone-beam computed tomography scans were taken and then analyzed by comparing postoperative changes in each group. RESULTS: The anteroposterior lengths at the uvula level (P2L) and epiglottis level (P3L) were significantly decreased in the symmetry group. The P2L was also significantly decreased in the asymmetry group, and a difference in the P3L was observed. However, there was no significant change in the width at the uvula level (P2W) and epiglottis level (P3W) in the symmetry group. In contrast, in the asymmetry group, P2W and P3W were significantly decreased. The cross-sectional ratio was significantly decreased P2 (P2L/P2W) and P3 (P3L/P3W) in the symmetry group. However, a statistically significant decrease occurred only at P3 in the asymmetry group. Anteroposterior positional changes of the menton and P2L (r = -0.370; P <.05), P3L (r = -0.414; P <0.05), and P3L/P3W (r = -0.361; P <0.05) were correlated. CONCLUSIONS: Differences in the morphologic features of the pharyngeal airway after bimaxillary surgery was observed in both the symmetry and asymmetry groups. Bimaxillary surgery with a mandibular setback in patients with skeletal Class III malocclusion worsened morbidity of the elliptical structure of the pharyngeal airway. However, it worsened less in the asymmetry group than in the symmetry group.

Evaluation of accuracy of 3-dimensional printed dental models in reproducing intermaxillary relational measurements: Based on inter-operator differences.

OBJECTIVE: Although, digital models have recently been used in orthodontic clinics, physical models are still needed for a multitude of reasons. The purpose of this study was to assess whether the printed models can replace the plaster models by evaluating their accuracy in reproducing intermaxillary relationships and by appraising the clinicians' ability to measure the printed models. METHODS: Twenty sets of patients' plaster models with well-established occlusal relationships were selected. Models were scanned using an intraoral scanner (Trios 3, 3Shape Dental System) by a single operator. Printed models were made with ZMD-1000B light-curing resin using the stereolithography method 3-dimensional printer. Validity, reliability, and reproducibility were evaluated using measurements obtained by three operators. RESULTS: In evaluation of validity, all items showed no significant differences between measurements taken from plaster and printed models. In evaluation for reliability, significant differences were found in the distance between the gingival zeniths of #23-#33 (DZL_3) for the plaster models and at #17-#43 (DZCM_1) for the printed models. In evaluation for reproducibility, the plaster models showed significant differences between operators at midline, and printed models showed significant differences at 7 measurements including #17-#47 (DZR_7). CONCLUSIONS: The validity and reliability of intermaxillary relationships as determined by the printed model were clinically acceptable, but the evaluation of reproducibility revealed significant inter-operator differences. To use printed models as substitutes for plaster models, additional studies on their accuracies in measuring intermaxillary relationship are required.

Lip line changes in Class III facial asymmetry patients after orthodontic camouflage treatment, one-jaw surgery, and two-jaw surgery: A preliminary study.

OBJECTIVE: To evaluate the effects of orthodontic camouflage treatment (OCT), one-jaw surgery, and two-jaw surgery on the correction of lip line cant (LLC) and to examine factors affecting the correction of LLC in Class III craniofacial asymmetry patients. MATERIALS AND METHODS: A sample of 30 Class III craniofacial asymmetry patients was divided into OCT (n = 10), one-jaw surgery (n = 10), and two-jaw surgery (n = 10) groups such that the pretreatment LLC was similar in each group. Pretreatment and posttreatment cone-beam computed tomography scans were used to measure dental and skeletal parameters and LLC. Pretreatment and posttreatment measurements were compared within groups and between groups. Pearson's correlation tests and multiple regression analyses were performed to investigate factors affecting the amount and rate of LLC correction. RESULTS: The average LLC correction was 1.00° in the one-jaw surgery group, and in the two-jaw surgery group, it was 1.71°. In the OCT group it was -0.04°, which differed statistically significantly from the LLC correction in the other two groups. The amount and rate of LLC correction could be explained by settling of skeletal discrepancies or LLC at pretreatment with goodness of fit percentages of approximately 82% and 41%, respectively. CONCLUSIONS: Orthognathic surgery resulted in significant correction of LLC in Class III craniofacial asymmetry patients, while OCT did not.

Comparison of cone-beam computed tomography cephalometric measurements using a midsagittal projection and conventional two-dimensional cephalometric measurements.

OBJECTIVE: This study investigated whether it is possible to use a two-dimensional (2D) standard in three-dimensional (3D) analysis, by comparing the angles and lengths measured from a midsagittal projection in 3D cone-beam computed tomography (CBCT) with those measured by 2D lateral cephalometric radiography (LCR). METHODS: Fifty patients who underwent both LCR and CBCT were selected as subjects. CBCT was reoriented in 3 different methods and the measuring-points were projected onto the midsagittal plane. Twelve angle values and 8 length values were measured on both LCR and CBCT and compared. RESULTS: Repeated measures analysis of the variance revealed statistically significant differences in 7 angular and 5 linear measurements among LCR and 3 types of CBCT (p < 0.05). Of these 12 measurements, multiple comparisons showed that 6 measurements (ANB, AB to FH, IMPA, FMA, Co-Gn, Go-Me) were not significantly different in pairwise comparisons. LCR was significantly different from 3 types of CBCT in 3 angular (SN to FH, interincisal angle, FMIA) and 2 linear (S-Go, Co-ANS) measurements. The CBCT method was similar for all measurements, except for 1 linear measurement, i.e., S-N. However, the disparity between the mean values for all parameters was within the range of clinical measurement error. CONCLUSIONS: 3D-CBCT analysis, using midsagittal projection, is a useful method in which the 2D-LCR normative values can be used. Although the measurements changed with reorientation, these changes were not clinically significant.

Three-dimensional cone beam computed tomographic image reorientation using soft tissues as reference for facial asymmetry diagnosis.

OBJECTIVE: To investigate discrepancies in results of facial asymmetry analysis using different cone beam computed tomography (CBCT) image reorientation methods and the effectiveness of soft tissue as a reorientation reference for analysis of facial asymmetry. MATERIALS AND METHODS: An asymmetric group of 30 patients with 4 mm or more of chin point (menton [Me]) deviation and a symmetric group of 30 patients with less than 4 mm of deviation of Me were chosen as study subjects. Three orientation methods were used to calculate and compare Me deviation values of the 60 subjects. Two methods used only skeletal landmarks for reference, and one method included the soft tissue landmarks around the eye. Preferences of an expert group for the facial midline as determined by each reorientation method were also examined. RESULTS: The examinations showed significant discrepancies in Me deviation values between the three reorientation methods. The expert group showed the greatest preference for the facial midline reorientation method that incorporated soft tissue landmarks of the eye. CONCLUSIONS: These study findings suggest that the inclusion of soft tissue landmarks, especially those around the eyes, is effective for three-dimensional CBCT image reorientation for facial asymmetry analysis.

Relationship between vertical skeletal pattern and success rate of orthodontic mini-implants.

INTRODUCTION: The objective of this research was to determine which clinical and skeletal factors are related to the success rate of orthodontic mini-implants in the maxillary and mandibular posterior buccal areas. METHODS: A total of 778 orthodontic mini-implants (Dual-Top Anchor System, Jeil Medical, Seoul, Korea; 1.6 mm diameter, 8 mm length, cylinder shape, self-drilling type) in 306 patients were retrospectively examined. The success rate was calculated according to clinical variables (sex, age, soft-tissue management, placement position, sagittal skeletal classification, arch-length discrepancy, and side) and skeletal variables (articular angle, mandibular plane to palatal plane angle, Frankfort-mandibular plane angle, mandibular plane angle, gonial angle, upper gonial angle, and lower gonial angle). Analysis of variance (ANOVA), chi-square tests, and multiple logistic regression analysis were used for statistical analysis. RESULTS: The overall success rate was 79.0%. Almost 80% of the failures occurred within the first 4 months. The clinical variables sex, age, soft-tissue management, sagittal skeletal classification, arch-length discrepancy, and side did not show significant differences in the success rate. Although the success rates were significantly different according to placement position (P <0.01), there was no significant difference in the odds ratios among placement positions. In the skeletal variables, average upper gonial angle (84.2%) had a significantly higher success rate than low (75.7%) and high (71.2%) upper gonial angles (P <0.01). High Frankfort-mandibular plane angle (P <0.05) and low upper gonial angle groups (P <0.05) showed significant lower odds ratios than did the other types. CONCLUSIONS: Vertical skeletal pattern might be an important factor for the success of orthodontic mini-implants placed in posterior buccal areas.

Factors associated with the success rate of orthodontic miniscrews placed in the upper and lower posterior buccal region.

OBJECTIVE: To determine the success rate and the factors related to the success rate of orthodontic miniscrew implants (OMI) placed at the attached gingiva of the posterior buccal region. MATERIALS AND METHODS: Four hundred eighty OMI placed in 209 orthodontic patients were examined retroactively. The sample was divided into young patients (range 10-18 years, N = 108) and adult patients (range 19-64 years, N = 109). The placement site was divided into three interdental areas from the first premolar to the second molar in the maxilla and mandible. According to soft tissue management, the samples were divided into incision and nonincision groups. Chi-square tests and multiple logistic regression analyses were used. RESULTS: The overall success rate was 83.8%. Dislodgement of the OMI occurred most frequently in the first 1-2 months, and more than 90% of the failures occurred within the first 4 months. Sex, age, jaw, soft tissue management, and placement side did not show any difference in the success rate. Placement site, however, showed a significant difference in the mandible of adult patients. There was no difference in the success rate in the maxilla. CONCLUSIONS: Placement site is one of the important factors for success rate of OMI.

Intrusion of overerupted molars by corticotomy and orthodontic skeletal anchorage.

This article describes the orthodontic treatment of a 26-year-old female patient with overerupted left maxillary molar teeth. Her chief complaint was that the maxillary left first and the second molar intruded into the space required for the mandibular left first and the second molars, preventing prosthodontic treatment. The authors performed a corticotomy and used orthodontic skeletal anchorage with a miniplate and orthodontic miniscrews with a head modified to provide a specially designed hook. With this approach, they were able to achieve a sufficient amount of molar intrusion without discomfort, root resorption, or extrusion of the adjacent teeth. The first molar was intruded 3.0 mm and second molar was intruded 3.5 mm during 2 months of treatment. These results have been maintained for 11 months.