RESUMO
Attempts to eliminate congenital dislocation of the hip by detecting it early have not been completely successful. It is not known why some infants, checked by competent examiners, still appear late with dislocations. The usual explanations of a mistake by the examiner, or of spontaneous dislocation of a hip that was stable at birth, do not explain why some centres succeed while others fail, or why good examiners may become less effective with experience. The explanation suggested is that the examination itself could be responsible and may actually cause a hip to become unstable.
Assuntos
Luxação Congênita de Quadril/diagnóstico , Erros de Diagnóstico , Luxação Congênita de Quadril/etiologia , Humanos , Recém-NascidoAssuntos
Lítio/administração & dosagem , Adolescente , Adulto , Idoso , Peso Corporal , Estudos de Avaliação como Assunto , Feminino , Humanos , Lítio/sangue , Masculino , Matemática , Métodos , Pessoa de Meia-Idade , Modelos BiológicosAssuntos
Epifise Deslocada/terapia , Adolescente , Pinos Ortopédicos/efeitos adversos , Criança , Epifise Deslocada/diagnóstico por imagem , Feminino , Necrose da Cabeça do Fêmur/etiologia , Humanos , Complicações Intraoperatórias , Masculino , Manipulação Ortopédica/efeitos adversos , Complicações Pós-Operatórias , Radiografia , Estudos RetrospectivosRESUMO
A cytokinin-binding protein has been isolated from wheat germ via ammonium sulfate precipitation, carboxymethyl Sephadex chromatography, and affinity chromatography on a column substituted with a derivative of kinetin riboside. On Sephadex G-200, the protein migrated with an apparent molecular weight of 122,000 daltons. The dissociation constant for kinetin was determined by equilibrium dialysis to be 1.2 micromolar; N(6)-benzylaminopurine and N(6)-(Delta(2)-isopentenyl)adenine were also strongly bound. Little affinity was exhibited toward either cis-zeatin or trans-zeatin.