Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 76
Filtrar
1.
Nature ; 569(7757): E9, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-31073227

RESUMO

Change history: In this Letter, the y-axis values in Fig. 3f should go from 4 to -8 (rather than from 4 to -4), the y-axis values in Fig. 3h should appear next to the major tick marks (rather than the minor ticks), and in Fig. 1b, the arrows at the top and bottom of the electron-scale current sheet were going in the wrong direction; these errors have been corrected online.

2.
Sci Rep ; 9(1): 5356, 2019 03 29.
Artigo em Inglês | MEDLINE | ID: mdl-30926833

RESUMO

The primary Brazilian malaria vector, Nyssorhynchus darlingi (formerly Anopheles darlingi), ranges from 0°S-23°S across three biomes (Amazonia, Cerrado, Mata Atlântica). Rising temperatures will increase mosquito developmental rates, and models predict future malaria transmission by Ny. darlingi in Brazil will shift southward. We reared F1 Ny. darlingi (progeny of field-collected females from 4 state populations across Brazil) at three temperatures (20, 24, 28 °C) and measured key life-history traits. Our results reveal geographic variation due to both genetic differences among localities and plastic responses to temperature differences. Temperature significantly altered all traits: faster larval development, shorter adult life and overall lifespan, and smaller body sizes were seen at 28 °C versus 20 °C. Low-latitude Amazonia mosquitoes had the fastest larval development at all temperatures, but at 28 °C, average development rate of high-latitude Mata Atlântica mosquitoes was accelerated and equivalent to low-latitude Amazonia. Body size of adult mosquitoes from the Mata Atlântica remained larger at all temperatures. We detected genetic variation in the plastic responses among mosquitoes from different localities, with implications for malaria transmission under climate change. Faster development combined with larger body size, without a tradeoff in adult longevity, suggests vectorial capacities of some Mata Atlântica populations may significantly increase under warming climates.


Assuntos
Características de História de Vida , Malária/epidemiologia , Mosquitos Vetores/fisiologia , Temperatura , Adaptação Fisiológica , Brasil , Geografia , Longevidade , Malária/prevenção & controle , Malária/transmissão , Mosquitos Vetores/parasitologia
3.
Science ; 362(6421): 1391-1395, 2018 12 21.
Artigo em Inglês | MEDLINE | ID: mdl-30442767

RESUMO

Magnetic reconnection is an energy conversion process that occurs in many astrophysical contexts including Earth's magnetosphere, where the process can be investigated in situ by spacecraft. On 11 July 2017, the four Magnetospheric Multiscale spacecraft encountered a reconnection site in Earth's magnetotail, where reconnection involves symmetric inflow conditions. The electron-scale plasma measurements revealed (i) super-Alfvénic electron jets reaching 15,000 kilometers per second; (ii) electron meandering motion and acceleration by the electric field, producing multiple crescent-shaped structures in the velocity distributions; and (iii) the spatial dimensions of the electron diffusion region with an aspect ratio of 0.1 to 0.2, consistent with fast reconnection. The well-structured multiple layers of electron populations indicate that the dominant electron dynamics are mostly laminar, despite the presence of turbulence near the reconnection site.

4.
Science ; 361(6406): 1000-1003, 2018 09 07.
Artigo em Inglês | MEDLINE | ID: mdl-30190400

RESUMO

Particle acceleration by plasma waves and spontaneous wave generation are fundamental energy and momentum exchange processes in collisionless plasmas. Such wave-particle interactions occur ubiquitously in space. We present ultrafast measurements in Earth's magnetosphere by the Magnetospheric Multiscale spacecraft that enabled quantitative evaluation of energy transfer in interactions associated with electromagnetic ion cyclotron waves. The observed ion distributions are not symmetric around the magnetic field direction but are in phase with the plasma wave fields. The wave-ion phase relations demonstrate that a cyclotron resonance transferred energy from hot protons to waves, which in turn nonresonantly accelerated cold He+ to energies up to ~2 kilo-electron volts. These observations provide direct quantitative evidence for collisionless energy transfer in plasmas between distinct particle populations via wave-particle interactions.

5.
Nature ; 557(7704): 202-206, 2018 05.
Artigo em Inglês | MEDLINE | ID: mdl-29743689

RESUMO

Magnetic reconnection in current sheets is a magnetic-to-particle energy conversion process that is fundamental to many space and laboratory plasma systems. In the standard model of reconnection, this process occurs in a minuscule electron-scale diffusion region1,2. On larger scales, ions couple to the newly reconnected magnetic-field lines and are ejected away from the diffusion region in the form of bi-directional ion jets at the ion Alfvén speed3-5. Much of the energy conversion occurs in spatially extended ion exhausts downstream of the diffusion region 6 . In turbulent plasmas, which contain a large number of small-scale current sheets, reconnection has long been suggested to have a major role in the dissipation of turbulent energy at kinetic scales7-11. However, evidence for reconnection plasma jetting in small-scale turbulent plasmas has so far been lacking. Here we report observations made in Earth's turbulent magnetosheath region (downstream of the bow shock) of an electron-scale current sheet in which diverging bi-directional super-ion-Alfvénic electron jets, parallel electric fields and enhanced magnetic-to-particle energy conversion were detected. Contrary to the standard model of reconnection, the thin reconnecting current sheet was not embedded in a wider ion-scale current layer and no ion jets were detected. Observations of this and other similar, but unidirectional, electron jet events without signatures of ion reconnection reveal a form of reconnection that can drive turbulent energy transfer and dissipation in electron-scale current sheets without ion coupling.

6.
Phys Rev Lett ; 121(26): 265101, 2018 Dec 28.
Artigo em Inglês | MEDLINE | ID: mdl-30636132

RESUMO

We study spectral features of ion velocity and magnetic field correlations in the magnetosheath and in the solar wind using data from the Magnetospheric Multiscale (MMS) spacecraft. High-resolution MMS observations enable the study of the transition of these correlations between their magnetofluid character at larger scales into the subproton kinetic range, previously unstudied in spacecraft data. Cross-helicity, angular alignment, and energy partitioning is examined over a suitable range of scales, employing measurements based on the Taylor frozen-in approximation as well as direct two-spacecraft correlation measurements. The results demonstrate signatures of alignment at large scales. As kinetic scales are approached, the alignment between v and b is destroyed by demagnetization of protons.

7.
Science ; 356(6341): 960-963, 2017 06 02.
Artigo em Inglês | MEDLINE | ID: mdl-28572393

RESUMO

The magnetopause deflects the solar wind plasma and confines Earth's magnetic field. We combine measurements made by the four spacecraft of the Magnetospheric Multiscale mission to demonstrate how the plasma and magnetic forces at the boundary affect the interaction between the shocked solar wind and Earth's magnetosphere. We compare these forces with the plasma pressure and examine the electron distribution function. We find that the magnetopause has sublayers with thickness comparable to the ion scale. Small pockets of low magnetic field strength, small radius of curvature, and high electric current mark the electron diffusion region. The flow of electrons, parallel and antiparallel to the magnetic field, reveals a complex topology with the creation of magnetic ropes at the boundary.

8.
Geophys Res Lett ; 43(10): 4841-4849, 2016 05 28.
Artigo em Inglês | MEDLINE | ID: mdl-27867235

RESUMO

We report on field-aligned current observations by the four Magnetospheric Multiscale (MMS) spacecraft near the plasma sheet boundary layer (PSBL) during two major substorms on 23 June 2015. Small-scale field-aligned currents were found embedded in fluctuating PSBL flux tubes near the separatrix region. We resolve, for the first time, short-lived earthward (downward) intense field-aligned current sheets with thicknesses of a few tens of kilometers, which are well below the ion scale, on flux tubes moving equatorward/earthward during outward plasma sheet expansion. They coincide with upward field-aligned electron beams with energies of a few hundred eV. These electrons are most likely due to acceleration associated with a reconnection jet or high-energy ion beam-produced disturbances. The observations highlight coupling of multiscale processes in PSBL as a consequence of magnetotail reconnection.

9.
Geophys Res Lett ; 43(10): 4716-4724, 2016 05 28.
Artigo em Inglês | MEDLINE | ID: mdl-27635105

RESUMO

New Magnetospheric Multiscale (MMS) observations of small-scale (~7 ion inertial length radius) flux transfer events (FTEs) at the dayside magnetopause are reported. The 10 km MMS tetrahedron size enables their structure and properties to be calculated using a variety of multispacecraft techniques, allowing them to be identified as flux ropes, whose flux content is small (~22 kWb). The current density, calculated using plasma and magnetic field measurements independently, is found to be filamentary. Intercomparison of the plasma moments with electric and magnetic field measurements reveals structured non-frozen-in ion behavior. The data are further compared with a particle-in-cell simulation. It is concluded that these small-scale flux ropes, which are not seen to be growing, represent a distinct class of FTE which is generated on the magnetopause by secondary reconnection.

10.
Science ; 352(6290): aaf2939, 2016 Jun 03.
Artigo em Inglês | MEDLINE | ID: mdl-27174677

RESUMO

Magnetic reconnection is a fundamental physical process in plasmas whereby stored magnetic energy is converted into heat and kinetic energy of charged particles. Reconnection occurs in many astrophysical plasma environments and in laboratory plasmas. Using measurements with very high time resolution, NASA's Magnetospheric Multiscale (MMS) mission has found direct evidence for electron demagnetization and acceleration at sites along the sunward boundary of Earth's magnetosphere where the interplanetary magnetic field reconnects with the terrestrial magnetic field. We have (i) observed the conversion of magnetic energy to particle energy; (ii) measured the electric field and current, which together cause the dissipation of magnetic energy; and (iii) identified the electron population that carries the current as a result of demagnetization and acceleration within the reconnection diffusion/dissipation region.

11.
Osteoporos Int ; 21(8): 1361-9, 2010 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-19802506

RESUMO

SUMMARY: This study examined whether 24 months of weight training exercises enhanced the effectiveness of risedronate, calcium, and vitamin D in maintaining or improving bone mineral density (BMD) in 223 postmenopausal breast cancer survivors. Subjects who were > or =50% adherent to exercise had no improvement in BMD but were less likely to lose BMD. INTRODUCTION: This study examined whether (1) postmenopausal breast cancer survivors (BCS) with bone loss taking 24 months of risedronate, calcium, and vitamin D had increased bone mineral density (BMD) at the total hip, femoral neck, L1-L4 spine, total radius and 33% radius, and decreased bone turnover; (2) subjects who also participated in strength/weight training (ST) exercises had greater increases in BMD and greater decreases in bone turnover; and (3) subjects who also exercised were more likely to preserve (at least maintain) BMD. METHODS: Postmenopausal BCS (223) were randomly assigned to exercise plus medication or medication only groups. Both groups received 24 months of 1,200 mg of calcium and 400 IU of vitamin D daily and 35 mg of risedronate weekly, and the exercise group additionally had ST exercises twice weekly. RESULTS: After 24 months, women who took medications without exercising had significant improvements in BMD at the total hip (+1.81%) and spine (+2.85%) and significant decreases in Alkphase B (-8.7%) and serum NTx (-16.7%). Women who also exercised had additional increases in BMD at the femoral neck (+0.29%), total hip (+0.34%), spine (+0.23%), total radius (+0.30%), and additional decreases in Alkphase B (-2.4%) and Serum NTx (-6.5%). Additional changes in BMD and bone turnover with exercise were not significant. Subjects who were > or =50% adherent to exercise were less likely to lose BMD at the total hip (chi-square [1] = 4.66, p = 0.03) and femoral neck (chi-square [1] = 4.63, p = 0.03). CONCLUSION: Strength/weight training exercises may prevent loss of BMD in postmenopausal BCS at risk for bone loss.


Assuntos
Densidade Óssea/fisiologia , Neoplasias da Mama/fisiopatologia , Osteoporose Pós-Menopausa/terapia , Treinamento Resistido/métodos , Adulto , Idoso , Antineoplásicos/efeitos adversos , Biomarcadores/sangue , Densidade Óssea/efeitos dos fármacos , Conservadores da Densidade Óssea/uso terapêutico , Remodelação Óssea/efeitos dos fármacos , Remodelação Óssea/fisiologia , Neoplasias da Mama/tratamento farmacológico , Cálcio/uso terapêutico , Quimioterapia Combinada , Ácido Etidrônico/análogos & derivados , Ácido Etidrônico/uso terapêutico , Feminino , Humanos , Pessoa de Meia-Idade , Força Muscular/fisiologia , Cooperação do Paciente , Equilíbrio Postural/fisiologia , Ácido Risedrônico , Vitamina D/uso terapêutico
12.
Science ; 326(5955): 962-4, 2009 Nov 13.
Artigo em Inglês | MEDLINE | ID: mdl-19833916

RESUMO

The dominant feature in Interstellar Boundary Explorer (IBEX) sky maps of heliospheric energetic neutral atom (ENA) flux is a ribbon of enhanced flux that extends over a broad range of ecliptic latitudes and longitudes. It is narrow (approximately 20 degrees average width) but long (extending over 300 degrees in the sky) and is observed at energies from 0.2 to 6 kilo-electron volts. We demonstrate that the flux in the ribbon is a factor of 2 to 3 times higher than that of the more diffuse, globally distributed heliospheric ENA flux. The ribbon is most pronounced at approximately 1 kilo-electron volt. The average width of the ribbon is nearly constant, independent of energy. The ribbon is likely the result of an enhancement in the combined solar wind and pickup ion populations in the heliosheath.

15.
Science ; 291(5504): 619-24, 2001 Jan 26.
Artigo em Inglês | MEDLINE | ID: mdl-11158668

RESUMO

The IMAGE spacecraft uses photon and neutral atom imaging and radio sounding techniques to provide global images of Earth's inner magnetosphere and upper atmosphere. Auroral imaging at ultraviolet wavelengths shows that the proton aurora is displaced equatorward with respect to the electron aurora and that discrete auroral forms at higher latitudes are caused almost completely by electrons. Energetic neutral atom imaging of ions injected into the inner magnetosphere during magnetospheric disturbances shows a strong energy-dependent drift that leads to the formation of the ring current by ions in the several tens of kiloelectron volts energy range. Ultraviolet imaging of the plasmasphere has revealed two unexpected features-a premidnight trough region and a dayside shoulder region-and has confirmed the 30-year-old theory of the formation of a plasma tail extending from the duskside plasmasphere toward the magnetopause.

16.
J Am Acad Nurse Pract ; 13(6): 276-84, 2001 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-11930870

RESUMO

PURPOSE: The overall purpose of this longitudinal 18-month study was to test the feasibility and effectiveness of a multicomponent intervention for prevention and treatment of osteoporosis. The purpose of this article is to describe the baseline bone mineral density (BMD) findings for 30 postmenopausal women and to compare these BMD findings to time since menopause, body mass index, and tamoxifen use. DATA SOURCES: Baseline data of BMD findings for 30 postmenopausal women, who have had a variety of treatments including surgery, adjuvant chemotherapy and or tamoxifen, and are enrolled in the 18-month longitudinal study. A demographic questionnaire and a three day dietary record were used to collect baseline data. CONCLUSIONS: Eighty percent of the women with breast cancer history had abnormal BMDs at baseline (t-scores below -1.00 SD). Thinner women showed a greater risk for accelerated trabecular bone loss at the spine and hip. IMPLICATIONS FOR PRACTICE: These findings suggest the need for early BMD assessments and for aggressive health promotion intervention strategies that include a multifaceted protocol of drug therapy for bone remodeling, 1500 mg of daily calcium, 400 IU vitamin D and a strength weight training program that is implemented immediately following chemotherapy treatment and menopause in this high risk population of women.


Assuntos
Densidade Óssea , Neoplasias da Mama/complicações , Osteoporose/prevenção & controle , Adulto , Idoso , Antineoplásicos Hormonais/uso terapêutico , Índice de Massa Corporal , Remodelação Óssea , Neoplasias da Mama/tratamento farmacológico , Cálcio/uso terapêutico , Feminino , Humanos , Estudos Longitudinais , Pessoa de Meia-Idade , Pós-Menopausa , Tamoxifeno/uso terapêutico , Vitamina D/uso terapêutico
17.
Australas Radiol ; 44(3): 349-50, 2000 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-10974736

RESUMO

Hip aspiration for exclusion of infection is a common procedure prior to revision arthroplasty. Some patients with total hip arthroplasties develop superomedial migration of the prosthesis, while others can have extensive heterotopic bone formation. The traditional approaches may be contraindicated due to overlying bowel or bone anterior/lateral to the prosthesis. These patients are candidates for the superolateral approach. With the patient supine marks are made on the skin at (i) the greater trochanter and (ii) a superior site that aligns with the neck of the prosthesis and soft-tissue window. The needle enters the lateral skin parallel to the table top. Usually only one pass is necessary.


Assuntos
Artroplastia de Quadril/efeitos adversos , Infecções Relacionadas à Prótese/diagnóstico , Sucção/métodos , Diagnóstico Diferencial , Humanos , Postura
18.
Radiol Clin North Am ; 35(3): 631-53, 1997 May.
Artigo em Inglês | MEDLINE | ID: mdl-9167666

RESUMO

This article addresses the place of MR imaging in the diagnosis of knee injuries. MR imaging of subtle fractures and bone contusions is described with emphasis placed on those types of fractures frequently associated with specific patterns of soft tissue injury. Soft tissue injuries are divided into ligamentous, meniscal, and muscular; each is discussed separately. The MR imaging appearance of these lesions is explained.


Assuntos
Fraturas Ósseas/diagnóstico , Fraturas de Cartilagem , Traumatismos do Joelho/diagnóstico , Imageamento por Ressonância Magnética , Lesões dos Tecidos Moles/diagnóstico , Osso e Ossos/lesões , Criança , Contusões/diagnóstico , Humanos , Ligamentos Articulares/lesões , Músculo Esquelético/lesões , Lesões do Menisco Tibial
19.
J Rheumatol ; 23(9): 1565-78, 1996 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-8877927

RESUMO

OBJECTIVE: To describe the association between hormonally related risk factors and the progression to new sites of radiographically defined full body (generalized) osteoarthritis (OA) in a cohort of older women. METHODS: A retrospective cohort design was used to study former radium dial painters over the age of 40 years who had minimal radium exposure. At study entry and at varying followup times, clinical examinations were conducted and full body radiographs were taken. Two followup groups were defined: women with a followup radiograph 1-9 years after baseline (n = 75) and 10-19 years after baseline (n = 53). Fifty-five joints (10 joint groups) were independently graded at baseline and followup for OA by the method of Kellgren and Lawrence, and provided the basis for summary full body OA progression scores. Progression was defined as an increase in the number of sites with OA and in separate analyses as an increase in the number of joint groups with OA. RESULTS: Increasing length of followup and lower baseline OA score were associated with greater OA progression, while age at baseline examination showed no clear relation to progression. Beyond these variables, increasing height and having ever smoked were inversely associated with OA progression, while body mass index (BMI) showed a weak positive association. In multivariable modeling for followup 1-9 years, only lower baseline OA score predicted greater OA progression to new sites (partial r2 = 0.13, p = 0.0009). In followup 10-19 years, baseline OA score (partial r2 = 0.12, p = 0.0011), height (partial r2 = 0.057, p = 0.033), and smoking status (partial r2 = 0.09, p = 0.035) were independent predictors of OA progression to new sites, while greater BMI was a positive, weak, and nonsignificant predictor (partial r2 = 0.031, p = 0.29). History of prior cholecystectomy, hysterectomy, dilation and curetage, number of pregnancies, and change in BMI were not significantly related to progression of OA to new sites. Similar results were found for predictors of OA progression to new joint groups. CONCLUSION: Lower baseline level of OA is associated with greater OA progression to new sites or joint groups independent of age, suggesting a "burnout" phenomenon. In addition, shorter height and having never smoked appear to be independent risk factors that predict the progression of radiographic OA to new sites or joint groups.


Assuntos
Osteoartrite/diagnóstico por imagem , Osteoartrite/fisiopatologia , Adulto , Envelhecimento/fisiologia , Estatura , Índice de Massa Corporal , Estudos de Coortes , Progressão da Doença , Feminino , Seguimentos , Previsões , Humanos , Estudos Longitudinais , Pessoa de Meia-Idade , Osteoartrite/patologia , Radiografia , Análise de Regressão , Estudos Retrospectivos , Fatores de Risco , Fumar , Fatores de Tempo
20.
Skeletal Radiol ; 25(4): 329-32, 1996 May.
Artigo em Inglês | MEDLINE | ID: mdl-8737996

RESUMO

Three cases of patellar fatigue fracture are reviewed. Two fractures presented with acute displacement and were initially thought to represent pathological fractures. Histological appearances in one case, and the clinical course in another, subsequently indicated that these were fatigue fractures. A third patient developed a chronic undisplaced fracture and followed the typical clinical course of fatigue fractures at other sites. The importance of recognizing patellar fatigue fractures and of differentiating spontaneously displaced fatigue fractures from pathological fractures is emphasized.


Assuntos
Fraturas de Estresse/diagnóstico por imagem , Patela/diagnóstico por imagem , Patela/lesões , Adolescente , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Radiografia
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...