[Factors that affect the dwell time of a central venous catheter]. / Factores que inciden sobre el tiempo de permanencia de un catéter endovenoso central.

OBJECTIVE: To determine the factors that affect the dwell time of a central venous catheter. BACKGROUND: The own immunodeficiency in cancer patient and the collateral effects of their treatment increase the probability of infection and reduce the time of use of a catheter. SUBJECTS: Incipient cohort of 306 patients with cancer, with an average age of 59 +/- 14.5 years. INTERVENTIONS: Time zero like the day of the placement of the catheter was defined. Daily clinical signs of infection by catheter looked for, with taking of simultaneous blood cultures every 7 days. The primary outcome was infection of the catheter and the alternative aim of treatment, obstruction or death of the patient. One compared the dwell time with the infected catheter versus non-infected and its relation with potential risk factors. RESULTS: 306 catheters were placed for a total of 4,043 to days/catheter, became infected 25 (8.2%). The global average survival was of 50 days. One was that to greater dwell time, greater it was the infection incidence. In the fit analysis of survival, the presence of remote infection (OR = 4.71, IC 95% = 1.7-10.1, p = 0.002) was the factor that showed a significant association. CONCLUSIONS: The time of life utility of a catheter is ample, limited by the presence of remote infection like factor of potential risk of infection by catheter.

Factores que inciden sobre el tiempo de permanencia de un catéter endovenoso central / Factors that affect the dwell time of a central venous catheter

Objetivo: Determinar los factores que inciden en el tiempo de permanencia de un catéter endovenoso central. Antecedentes: En el paciente con cáncer existen factores propios del estado de inmunocompromiso por el tumor y los efectos colaterales de su tratamiento que aumentan la probabilidad de infección y consecuentemente reducen el tiempo de uso de un catéter. Sujetos: Se integró una cohorte de 306 pacientes con cáncer, con una edad promedio de 59 ± 14,5 años. Intervenciones: Se definió tiempo cero como el día de colocación del catéter. Diariamente se buscaron signos clínicos de infección por catéter, con toma de hemocultivos simultáneos cada 7 días. El desenlace primario fue infección del catéter y el alternativo fin de tratamiento, obstrucción o fallecimiento del paciente. Se comparó el tiempo de permanencia del catéter infectado vs no infectado y su relación con factores de riesgo potenciales. Resultados: Se colocaron 306 catéteres para un total de 4.043 días/catéter. Se infectaron 25 (8,2%). La sobrevida media global fue de 50 días. Se encontró que a mayor tiempo de permanencia, mayor fue la incidencia de infección. En el análisis de sobrevida ajustado, la presencia de infección a distancia (OR = 4,71, IC95% = 1,7-10,1, p = 0,002) fue el factor que mostró una asociación significativa. Conclusiones: El tiempo de vida útil de un catéter es amplia, limitada por la presencia de infección a distancia como factor de riesgo potencial de infección por catéter (AU)

Objective: To determine the factors that affect the dwell time of a central venous catheter. Background: The own immunodeficiency in cancer patient and the collateral effects of their treatment increase the probability of infection and reduce the time of use of a catheter. Subjects: Incipient cohort of 306 patients with cancer, with an average age of 59 ± 14.5 years. Interventions: Time zero like the day of the placement of the catheter was defined. Daily clinical signs of infection by catheter looked for, with taking of simultaneous blood cultures every 7 days. The primary outcome was infection of the catheter and the alternative aim of treatment, obstruction or death of the patient. One compared the dwell time with the infected catheter versus non infected and its relation with potential risk factors. Results: 306 catheters were placed for a total of 4,043 to days/catheter, became infected 25 (8.2%). The global average survival was of 50 days. One was that to greater dwell time, greater it was the infection incidence. In the fit analysis of survival, the presence of remote infection (OR= 4.71, IC 95% = 1.7-10.1, p = 0.002) was the factor that showed a significant association. Conclusions: The time of life utility of a catheter is ample, limited by the presence of remote infection like factor of potential risk of infection by catheter (AU)