RESUMO
Mujer de 67 años, sin antecedentes patológicos de interés, que consultó por la aparición en abdomen de placas eritematovioláceas con patrón reticular y aspecto contusiforme. Destacaba la presencia en la superficie de las mismas de lesiones papulovesiculosas aisladas de contenido serosanguinolento. El estudio histopatológico demostró que se trataba de metástasis cutáneas de un adenocarcinoma ovárico (AU)
Assuntos
Adenocarcinoma/história , Ovário , Metástase NeoplásicaRESUMO
We report the case of a 28-year-old woman attending for hirsutism and diabetes mellitus. Diabetes was a casual finding 2 years before consulting and was treated with diet and antidiabetic drugs. Acromegalic appearance, facial acne, penty, curled and rude hair, hypertrichosis, ade I diffuse goitre, prominent abdomen with umbilical hernia, severe hepatomegaly, prominent muscles and veins with normal genitalia appeared in the physical examination. No other abnormalities were found. Hypophysis, thyroid, suprarenal and ovaric hormonal functional studies were normal. An insulin-resistant diabetes mellitus was found in the metabolic study. Ultrasound and TAC showed severe diffuse hepatomegaly and visceral fat lack. Bone radiographies showed diffuse lesions compatible with polyostotic dysplasia. Subcutaneous, hepatic and bone biopsy revealed lack of fat tissue, hepatic steatosis and osteal fibrosis. Patient s diagnosis was Berardinelli-Seip syndrome, Seip-Lawrence or lipoatrophic diabetes associated with polyostotic fibrotic dysplasia. Case is studies and bibliographic references are reviewed.
Assuntos
Diabetes Mellitus Lipoatrófica/complicações , Displasia Fibrosa Poliostótica/complicações , Adulto , Feminino , HumanosRESUMO
Kawasaki syndrome is not usual in our country. We report this case to stress the clinical importance of this syndrome in which dermatological signs predominate.
Assuntos
Síndrome de Linfonodos Mucocutâneos/patologia , Dermatopatias/patologia , Humanos , Lactente , MasculinoRESUMO
Therapeutic action of bornaprine on localized forms of hyperhidrosis is studied in 12 patients. 50% improved after a week treatment. Other patients showed an acceptable change in the third or fourth week. Side effects only appeared in one patient.
Assuntos
Hidrocarbonetos Aromáticos com Pontes/uso terapêutico , Hiperidrose/tratamento farmacológico , Parassimpatolíticos/uso terapêutico , Adulto , Avaliação de Medicamentos , Feminino , Humanos , MasculinoRESUMO
The authors studied 5 cases of the actinic keratoses, 3 cases of the leukoplakia and 2 cases of the cutaneous horn with the lectins specifics on the oligosaccharides of the keratinocyte's membrane. The patterns in each disease are described according to grade of differentiation.
Assuntos
Oligossacarídeos/análise , Lesões Pré-Cancerosas/análise , Neoplasias Cutâneas/análise , Membrana Celular/análise , Humanos , Ceratose/metabolismo , Ceratose/patologia , Leucoplasia/metabolismo , Leucoplasia/patologia , Lesões Pré-Cancerosas/patologia , Neoplasias Cutâneas/patologiaRESUMO
The authors studied the oligosaccharides coated membrane of normal keratinocytes with the lectins HPA, PHA-L, RCA-120; and ConA. The results permit to have a pattern of normally epidermic differentiation.
Assuntos
Epiderme/ultraestrutura , Lectinas , Oligossacarídeos/análise , Diferenciação Celular , Membrana Celular/análise , Humanos , Queratinas/biossínteseRESUMO
The authors studied with the technic of PAP a case of the Paget extramammary. The presence of the precursors of the human milk in these cells in a date for to thing than Paget extramammary is the origin eccrine or apocrine.
Assuntos
Doença de Paget Extramamária/patologia , Idoso , Mama/citologia , Epiderme/patologia , Epiderme/ultraestrutura , Humanos , Técnicas Imunoenzimáticas , Microscopia EletrônicaRESUMO
Three cases of pseudocyst of the auricle were studied. All three occurred in male, 38, 54, and 23 years old; all had a solitary nodule of the anthelix. Such pseudocyst have a characteristic localization and are not caused by trauma and have a serous, cystic content. The cystic formations develop from degeneration and liquefaction within the auricular cartilage. We believe that the name proposed by Engel "pseudocyst of the auricle" can be appropriated.