1.
Chem Commun (Camb)
; 56(50): 6830-6833, 2020 Jun 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32432293
RESUMO
The modification of lipid A with cationic 4-amino-4-deoxy-l-arabinose residues serves to confer resistance against cationic peptide antibiotics in Gram-negative bacteria. In this work, the enzyme ArnD is shown to act as a metal-dependent deformylase in the biosynthesis of this carbohydrate.