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Gastroenterol Hepatol ; 18(8): 413-6, 1995 Oct.
Artigo em Espanhol | MEDLINE | ID: mdl-7584780

RESUMO

Veno-occlusive liver disease (VOLD) is a cause of portal hypertension by non thrombotic obstruction of hepatic venous drainage attributed to multiple etiologies (toxic, irradiation, antineoplastic, conditioning for bone marrow transplantation). One case of VOLD in a senile patient due to continuous two year consumption of Senecio vulgaris tea is reported. This compound, which has a high pyrrolizidine alkaloid content induced a subacute course of portal hypertension and death. The clinicopathologic features of VOLD and the etiopathogenesis in relation to the pyrrolizidine alkaloids present in Senecio vulgaris are discussed. The need for considering the history of medicinal plant ingestion in patients under portal hypertension studies are strongly recommended as is the advice regarding the possible dangers involved in the inappropriate use of remedies provided by herbalists.


Assuntos
Bebidas/efeitos adversos , Hepatopatia Veno-Oclusiva/induzido quimicamente , Plantas Tóxicas , Alcaloides de Pirrolizidina/efeitos adversos , Senécio , Idoso , Biópsia , Hepatopatia Veno-Oclusiva/complicações , Hepatopatia Veno-Oclusiva/patologia , Humanos , Hipertensão Portal/etiologia , Fígado/patologia , Masculino
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