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Hinyokika Kiyo ; 54(8): 557-9, 2008 Aug.
Artigo em Japonês | MEDLINE | ID: mdl-18788447

RESUMO

A 52-year-old woman was referred to our hospital for treatment of urachal cancer. She complained of supurapubic dull pain and gross hematuria. Computed tomography and magnetic resonance imaging showed a non-papillary sessile tumor, which was located on the dome of the bladder and invaded the small intestine. The tumor was diagnosed as Sheldon's stage IIIC urachal cancer. After three courses of neoadjuvant chemotherapy with FOLFOX4 (oxaliplatin, 5-FU and leukovolin), the tumor was reduced from 7 x 6 cm to 5.5 x 5 cm in size. Consequently, the patient underwent an en-bloc resection of the urachal tumor with the dome of the bladder and the parts of the ileum invaded by the tumor. One course of adjuvant chemotherapy (FOLFOX4) was performed. Surgical specimen revealed histologically well differentiated squamous carcinoma and invasion to the propria of the ileum. The surgical margins were negative for the cancer. For 1.5 years after the surgery, no local recurrence or distant metastasis has been observed.


Assuntos
Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Carcinoma de Células Escamosas/tratamento farmacológico , Neoplasias do Íleo/tratamento farmacológico , Terapia Neoadjuvante , Úraco , Neoplasias da Bexiga Urinária/tratamento farmacológico , Protocolos de Quimioterapia Combinada Antineoplásica/administração & dosagem , Carcinoma de Células Escamosas/cirurgia , Feminino , Fluoruracila/administração & dosagem , Humanos , Neoplasias do Íleo/cirurgia , Leucovorina/administração & dosagem , Pessoa de Meia-Idade , Invasividade Neoplásica , Compostos Organoplatínicos/administração & dosagem , Resultado do Tratamento , Neoplasias da Bexiga Urinária/cirurgia
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