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Brain Cogn ; 53(2): 197-201, 2003 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-14607147

RESUMO

A large debate has recently focused on the componential nature of the working-memory system (), as evidenced by functional-imaging studies and by using more sophisticated experimental paradigms. The present work aims at further disentangling the role and effects of central executive (CE) and of phonological loop (PL). It is suggested that maintaining active verbal information mostly relates to an intact PL, while the inhibition of interfering information preponderantly involves the CE. To distinguish these effects, two groups of brain damaged patients were administered with an updating task. Frontal lobe patients showed major difficulties in inhibiting interfering information, an ability requiring an involvement of the CE component. In contrast, Alzheimer's dementia patients evidenced a relative impairment in maintaining relevant information, requiring the intervention of the PL.


Assuntos
Doença de Alzheimer , Neoplasias Encefálicas/fisiopatologia , Lobo Frontal/fisiopatologia , Inibição Psicológica , Transtornos da Memória/etiologia , Transtornos da Memória/fisiopatologia , Adulto , Idoso , Neoplasias Encefálicas/complicações , Neoplasias Encefálicas/cirurgia , Feminino , Lobo Frontal/cirurgia , Humanos , Masculino , Transtornos da Memória/diagnóstico , Fonética , Índice de Gravidade de Doença
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