RESUMO
Surgical treatment is considered the last option for chronic tennis elbow. The purpose of this pilot study was to compare treatment with botulinum toxin infiltration of the wrist extensor, a less invasive method, with a surgical wrist extensor release (Hohmann operation). Forty patients were included in the prospective randomized study; one group of patients had surgery (n = 20), the other group of patients was treated with botulinum toxin (n = 20). The results of evaluations after 3, 6, 12, and 24 months are presented. One year after treatment 13 (65%) patients in the botulinum toxin group and 15 (75%) patients in the operative group had good to excellent results. Two years after treatment 15 patients in the botulinum toxin group (75%) had good to excellent results; four patients had been operated on after initial treatment with botulinum toxin Type A. Seventeen patients in the operative group scored good to excellent (85%) at 2 years. When analyzed with an overall scoring system, no differences were found between the two forms of treatment. Botulinum toxin infiltration, a less invasive technique, may be an alternative for surgical treatment of tennis elbow.
Assuntos
Toxinas Botulínicas Tipo A/administração & dosagem , Cotovelo de Tenista/terapia , Adulto , Idoso , Doença Crônica , Humanos , Injeções Intra-Articulares , Pessoa de Meia-Idade , Dor , Estudos Prospectivos , Amplitude de Movimento Articular , Cotovelo de Tenista/cirurgia , Resultado do TratamentoAssuntos
Antidiscinéticos/uso terapêutico , Toxinas Botulínicas/uso terapêutico , Cotovelo de Tenista/tratamento farmacológico , Adulto , Antidiscinéticos/administração & dosagem , Toxinas Botulínicas/administração & dosagem , Doença Crônica , Feminino , Humanos , Injeções Intramusculares , Masculino , Pessoa de Meia-IdadeRESUMO
Monomeric (iohexol 300 mg I/ml) and dimeric (iodixanol 270 mg I/ml) nonionic contrast media were compared in a double-blind, randomised, parallel group trial. Safety and efficacy of the media in intra-arterial cerebral digital subtraction angiography were evaluated by assessing adverse events, discomfort, EEG, heart rate and quality of radiodiagnostic information. Seventy-six patients underwent selective injection of the carotid and/or vertebral arteries. Both contrast media were well tolerated. No serious adverse events occurred. No effects on heart rate and EEG were evident. The arteriograms were of high quality and overall diagnostic information was optimal in 94% of the examinations. No clinically important differences between the two contrast media were found.