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3.
Ann Plast Surg ; 53(3): 250-5, 2004 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-15480012

RESUMO

We performed an anatomic study on 20 fresh lower limbs. Resin was injected in the popliteal artery. Medial sural artery perforator flaps were sculptured according to anatomic markings. On average, length of flaps was 12.9 cm, width was 7.9 cm; all 38 perforators were musculocutaneous: 1 perforator was always found (on average, 1.9 per flap). All perforators gathered between 7 and 18 cm from the popliteal crease; 34.2% of perforators arose on the midline of the medial head of gastrocnemius muscle; before entering the fascia, the perforator artery diameter was on average 0.5 mm. Two configurations of the intramuscular course of perforators were found. Sixty-six percent of perforators originated from the lateral branch of the medial sural artery, 34% from the medial one. These results improve the anatomic knowledge of the medial posterior calf region and allow us to describe a convenient plan to make flap sculpturing easier.


Assuntos
Artérias/anatomia & histologia , Perna (Membro)/irrigação sanguínea , Músculo Esquelético/irrigação sanguínea , Retalhos Cirúrgicos/irrigação sanguínea , Cadáver , Humanos
4.
Curr Med Res Opin ; 20(3): 403-8, 2004 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-15025849

RESUMO

OBJECTIVE: The article presents the results of a pilot study performed to evaluate the efficacy of polydeoxyribonucleotides (PDRNs) in shortening the healing times of autologous skin graft donor sites. RESEARCH DESIGN, METHODS: Two groups of patients were studied, the PDRN group (n = 20) and a control group (n = 20). In the control group dressings were performed with non-adherent gauzes and bulky gauzes with cloramine solution, whereas in the PDRN group a PDRN ointment was spread under the same medication as the controls. RESULTS: In the PDRN group, dressing procedures were not painful (whereas in the controls they often were), re-epithelialisation occurred earlier (12.5 vs 24.45 days) and there were no infections (9 in the controls). CONCLUSIONS: Results are encouraging for the use of PDRNs in shortening the healing times of autologous skin graft donor sites, although further studies are necessary to obtain clinically relevant results.


Assuntos
Fármacos Dermatológicos/farmacologia , Polidesoxirribonucleotídeos/farmacologia , Transplante de Pele/métodos , Cicatrização/efeitos dos fármacos , Ferimentos e Lesões/tratamento farmacológico , Adulto , Idoso , Idoso de 80 Anos ou mais , Fármacos Dermatológicos/uso terapêutico , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Projetos Piloto , Polidesoxirribonucleotídeos/uso terapêutico , Fatores de Tempo , Doadores de Tecidos , Resultado do Tratamento
10.
Dermatol Surg ; 29(12): 1222-4, 2003 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-14725667

RESUMO

BACKGROUND: Calcinosis cutis, a disease characterized by the presence of calcium deposits in the skin, is classified into four types according to etiology: dystrophic, metastatic, iatrogenic and idiopathic. The dystrophic form is the most common while the idiopathic one is the rarest, but specific incidence and frequency data are not available in scientific literature. OBJECTIVE: Calcinosis cutis circumscripta is a very rare form of idiopathic calcinosis cutis arising in the second half of life. It typically involves the extremities and is associated with prior trauma and scleroderma. We dealt with a very rare form of calcinosis cutis circumscripta in a healthy patient, for whom surgical excision revealed to be an effective and successful treatment. METHODS AND MATERIALS: We present the case of a 46-year-old woman affected by idiopathic circumscripta calcinosis cutis of the left knee, successfully treated by surgical removal. DISCUSSION: Medical and surgical treatment are options to cure calcinosis cutis. Medical therapy is not very effective. Surgical excision has shown to be beneficial, as it can provide a symptomatic relief. However, since calcinosis cutis limits are not always well defined a recurrence of the lesions may occur.


Assuntos
Calcinose/patologia , Dermatopatias/patologia , Adulto , Feminino , Humanos , Joelho
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