The impact on health-related quality of life from non-steroidal anti-inflammatory drugs, methotrexate, or steroids in treatment for juvenile idiopathic arthritis.

OBJECTIVE: To assess and compare the impact of medication treatments on health-related quality of life (HRQOL), family function, and medical status in children with juvenile idiopathic arthritis (JIA). METHODS: Fifty-seven children diagnosed with JIA were assessed by a pediatric rheumatologist and placed into one of three treatment groups: (1) non-steroidal anti-inflammatory; (2) methotrexate; or (3) steroids via IV methylprednisolone. Questionnaires were administered at baseline and 4-month follow-up. The attending pediatric rheumatologist provided additional medical information. RESULTS: Data document the impact of JIA on HRQOL, particularly on physical and pain domains. Steroid patients experienced improved HRQOL at follow-up relative to other groups, despite reporting more problems with side effects. CONCLUSION: These results demonstrate positive benefits of steroids in treating JIA children, despite the greatest incidence of adverse side effects.

Do you see what I see? Looking at scoliosis surgical outcomes through orthopedists' eyes.

STUDY DESIGN: A prospective study evaluated orthopedists' ratings of preoperative and postoperative cosmesis in adolescents undergoing posterior or anterior spinal fusion for idiopathic scoliosis. Measures evaluated how orthopedists rated outcome in relation to patient satisfaction with the surgical result. SUMMARY OF BACKGROUND DATA: The reliability of physician-derived data as a method for evaluating scoliosis surgical outcomes has not been sufficiently explored and has not been related to patient satisfaction ratings with the postoperative result. OBJECTIVES: The purpose of this study was to determine 1) the intrarater and interrater reliability estimates of orthopedists' ratings of scoliosis surgical outcomes and 2) the association between orthopedists' ratings and patient satisfaction ratings with the postoperative cosmesis. METHODS: Six orthopedists independently rated preoperative and postoperative color slides for cosmetic deformity in 41 patients with adolescent idiopathic scoliosis. Patients rated their satisfaction with the postoperative cosmesis 5 to 11 months after surgery. RESULTS: The intrarater and interrater reliabilities of orthopedists' assessments of scoliosis surgical outcomes ranged from fair to poor. Orthopedists' assessments of postoperative shoulder asymmetry significantly correlated with patient satisfaction ratings of cosmetic appearance following surgical correction of severe curves. Patient satisfaction ratings were unrelated to orthopedists' ratings of scar appearance, cosmetic deformity, and preoperative to postoperative cosmetic change. CONCLUSIONS: Intrarater and interrater reliability estimates were unacceptably low when evaluating spinal surgical outcomes in these 41 patients. Overall, orthopedists' ratings were not significantly correlated with patient satisfaction ratings of the postoperative result.