[Psychological characteristics of the motivation for alcohol use in adolescents]. / Psikhologicheskaia kharakteristika motivatsii potrebleniia alkogolia u podrostkov.

The authors describe the results of studying into the general motivation tension in situations connected with search of alcohol and the types of alcohol use motivation in adolescents with the signs of early alcoholism (group I), in those undergoing the stage of "assimilation of stereotypes of alcoholic behavior" (group II), and in the pupils of forms 7 to 10 of schools providing general education (controls). The data were obtained with the aid of a questionnaire on studying alcohol use motivation, modified by the authors. The data obtained disclose certain psychological characteristics of early alcoholism formation and the types of alcoholic motivation in adolescents. They promote a differentiated approach to the diagnosis of early alcoholization and alcoholism.

[Comparative effectiveness of the combined use of fenazepam, haloperidol, lithium and metabolic preparations in treating the psychopathologic disorders with obsessions in slowly progressive schizophrenia]. / Sravnitel'naia éffektivnost' kompleksnogo primeneniia fenazepama, galoperidola, litiia i metabolicheskikh preparatov v lechenii psikhopatologicheskikh rasstroistv s naviazchivostiami pri maloprogredientnoi shizofrenii.

The effectiveness of combined phenazepam, lithium, haloperidol and metabolic drugs (alpha-tocopherol, pyridoxal phosphate, nicotinamide) treatment of patients with slow progredient schizophrenia is analyzed. The psychotropic drugs were administered at doses lower below mean therapeutic ones by 1/2 to 1/3. Combined therapy proved effective even in the cases resistant to active antipsychotic treatment. No considerable untoward effects (extrapyramidal disorders) were found. The therapy had a differentiated impact on the obsessive syndrome and other borderline psychopathologic states. These advantages allow one to recommend the therapy for long-term support in schizophrenic patients with benign course of the disease.

[Modelling psychosis in cats by creating a generator of pathologically enhanced excitation in one of the septal nuclei]. / Modelirovanie psikhoza u koshek putem sozdaniia generatora patologicheski usilennogo vozbuzhdeniia v odnom iz iader septal'noi oblasti.

The experiments on adult freely behaving cats have shown that the injection of penicillin into the internal part (TI) of bed nucleus of stria terminalis (BST) caused the formation of the generator of pathologically enhanced excitation (GPEE). This part of BST became hyperactive and played the role of a pathologic determinant which caused the formation of a complex pathologic system and behavioural disorders with catatonia, stereotypy, food rejection, eating of uneatable things, hypoalgesia, zoosocial behavioural changes, depression of different emotions, etc. The development of these disorders was progressing and was accompanied by corresponding electrophysiological activity in TI and other brain structures studied. Coagulation of GPEE zone at the early stages of the process prevented the development of the above disorders.

[Complex use of phenazepam, lithium and haloperidol in the treatment of several forms of schizophrenia]. / Kompleksnoe primenenie fenazepama, litiia i galoperidola dlia lecheniia nekotorykh form shizofrenii.

The effectiveness of phenazepam, lithium and haloperidol used in combination was studied in schizophrenic patients with different courses of the disease. These drugs were used in doses lower than average therapeutic doses usually employed. The multiple modality therapy studied proved to be effective even in those cases where the patients had been resistant to earlier conducted active antipsychotic methods of treatment. In addition, there were no marked side effects in the form of extrapyramidal disorders. The follow-up study showed that the use of this treatment modality, having no effect on the progression of the schizophrenic process, may serve as a method of choice. This therapy has a number of advantages as compared with other treatments.