[An efficacy and tolerance study of transdermal estrogen replacement therapy with the preparation Systen R50 (Cilag)]. / Prouchvane vurkhu efikasnostta i ponosimostta na transdermalnata estrogen-zamestitelna terapiia s preparata Systen R50 (Cilag).

Results from the first study, carried out in our country on the therapeutic effects of Systen [correction of System] R50 TTS in women with peri- and postmenopausal symptoms are reported. Eight women with postcastration syndrome and seven women older than 50 years, with an intact uterus and no vaginal symptoms are reported. Eight women with postcastration syndrome and seven women older than 50 years, with an intact uterus and no vaginal bleeding for at least 6 months were treated. Progesterone was prescribed in the non-hysterectomised patients. In all women enrolled in the study the application of the preparation Systen [correction of System] R50 TTS led to a significant improvement of peri- and postmenopausal symptoms without serious side effects.

[Occupational damage to fertility in welders]. / Profesionalno uvrezhdane na fertiliteta pri oksizhenisti.

The aim of the present study is to establish whether there is difference in the quality of the sperm of welders in comparison with members of other professions without potential occupational risks. There were examined 30 welders and a control group of 159 males. In all participants in the study by means of the case history and clinical examination the presence of other pathogenic factors besides the occupational influences was excluded. The percentage part of the males with deviations in the sperm mobility and morphology was significantly higher in the group of welders as compared with the control group (p < 0.001). There were discussed the possible mechanisms which can be responsible for the found changes.

[Changes in the fertility indices among professional drivers]. / Promeni vuv fertilitetnite pokazateli pri profesionalnite shof'ori.

With the purpose of studying the supposed risk for the male inseminative ability, the fertile indices of 80 professional drivers (main group) and 159 representatives of professions accepted as not having professional harms (control group) have been examined. The results show significantly higher percentage part for the drivers with disturbed inseminative ability (66.25%) compared to the males of the control group (35.85%)-(P < 0.001). The date for the frequency of pyospermia are analogical: 28.75% of the drivers versus 16.98% of the control group (P < 0.05). Statistically main differences in the percentage distribution among the smokers, sufferers from chronic prostate or varicocele, carriers of pathogenic microorganisms in the sperm are not noticed, but in all these cases there is an unfavourable tendency for the drivers. The representatives of this widely spread profession among men have to be warned of the risk for possible changes in the fertility.

[Asymptomatic bacteriospermia in men in infertile families]. / Bezsimptomna bakteriospermiia pri muzhe ot bezplodni semeistva.

Bacteriological research of sperm has been done in 160 asymptomatic men from infertile families. A tendency of greater frequency of pathogenetic microorganisms is seen in persons with infringed inseminated capability, but the difference with the control group is not significant. The increased quantity of leucocytes in the sperm of asymptomatic men is not compulsory connected with pathological bacteriological find. The limited diagnostic value of routine microbiological research of sperm in men without symptoms of genital infection has been discussed.

[Abdominal delivery in the practice of the Obstetrical Clinic of the Medical University of Pleven (1976-1990)]. / Abdominalno rodorazreshenie v praktikata na Klinika po akusherstvo kum Meditsinski univeritet Pleven (1976-1990).

The authors have made a profound analysis of the abdominal parturition for a period of time including 15 years. The results in the newborn babies were investigated in parallel. From 3145 SC in neonatological period, 57 babies died. The tendency of widening of the indications for abdominal operative parturition for prematurely born children must be conformed to the conditions of the Center of Perinatology for intensive cares and treatment.

[Sperm quality in smokers and nonsmokers among infertile families]. / Kachestvo na spermata pri pushchi i nepushachi ot infertilni semeistva.

In 169 men from infertile couples were investigated the following sperm parameters--concentration, motility, morphology, in order to find the possible influence of smoking on sperm quality. The percentage of men with deviations from normal sperm motility is significantly higher among smokers (35.65%) in comparison with the non-smokers group (20.04%), p < 0.05. We found a higher percentage of men with changes in sperm morphology among smokers (40.00%) in comparison with non smokers. As for the concentration of spermatozoa, no significant difference was found between the two groups. We came to the conclusion that there exists a trend of increase of the percentage of men with deviations in motility and morphology with the increase of the cigarettes smoked per day.

[Primiparae--the role of age on the duration and disorders in the progression of labor]. / Purvorazhdashti--roliata na vuzrastta vurkhu produlzhitelnostta i narusheniiata v progresiiata na razhdanieto.

The authors have made a study of age influence on the delivery duration and the breaches of delivery progress by women giving birth for the first time. In 6 groups 742 first birth giving women are investigated. The authors have found out a correlation between the age growth, particularly after 25 years, and the total delivery duration increase. Using the Friedman's partogram, the delivery activity have been analyzed. Significance of delivery progress breaches are found out mostly during the active phase-protracted active phase and secondary protracted active phase. There wasn't found out correlations between the age and growth and the latent phase protraction, and the arrest disorders.