[Gas chromatography analysis of lipoprotein fatty acids in patients with myocardial infarction]. / Gazokhromatograficheskii analiz zhirnykh kislot lipoproteinov pri infarkte miokarda.

Presents a gas chromatographic analysis of lipid fatty acid composition and levels of free cholesterol in high-density and low-density lipoproteins (HDLP and LDLP) of patients with myocardial infarction with and without Q wave. The most expressed changes in the lipid fatty acid composition both in HDLP and LDLP were revealed in the patients without Q wave.

[T-lymphocyte functional activity in myocardial infarct patients with different clinical courses (based on data from fluorescent nuclear probing)]. / Sostoianie funktsional'noi aktivnosti T-limfotsitov u bol'nykh infarktom miokarda s razlichnym klinicheskim techeniem (po dannym fliuorestsentnogo zondirovaniia iader).

Overall thirty patients with acute Q-wave myocardial infarction (AMI) were studied. There were ten cases among them of uncomplicated AMI, eight ones of AMI presenting with arrhythmias, 12 patients suffered from AMI complicated by acute left ventricular failure. The functional state of T-lymphocytes was studied with the aid of the fluorescent nucleus probing with acridine orange. At day 1 to 3 Q-wave AMI the synthetic activity of T-lymphocytes was found out to be on the decrease. By day 14 to 16, patients with AMI running a complicated course had high values for metabolic activity of T-lymphocytes, which fact might be indicative of poor prognosis.

[The role of free radical processes in the development of autosensitization in ischemic heart disease]. / Rol' svobodnoradikal'nykh protsessov v razvitii autosensibilizatsii pri ishemicheskoi bolezni serdtsa.

Derangement in freeradical processes (FRP) and lipid metabolism is known to occur in ischemic heart disease. Since autoimmune component appear to play an important role in the pathogenesis of IHD, the contributers to the article studied the state of freeradical processes in IHD patients during development of autosensibilization. A total of 42 patients with unstable angina and 8 essentially healthy subjects were examined. The blood level of FRP, antioxidant protection were determined using chemiluminometry technique. The blood serum content of free cholesterol and phospholipid fatty acid composition were evaluated by gas-liquid chromatography, the T- and B-lymphocyte functional status by fluorescent probing with acridine orange. The level of autoantibodies was determined as recommended by Boiden. The lymphocyte circulating population functional activity was found to be related to the state of FRP, antioxidant protection and the blood serum lipidic complex composition.