1.
J Nat Prod
; 62(2): 345-7, 1999 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-10075783
RESUMO
Bioassay-guided fractionation of the EtOH extract of M. africana, using the in vivo noninsulin-dependent diabetes mellitus db/db mouse model, resulted in the isolation of the new daphnane-type diterpenoid maprouneacin (2). Compound 2 showed potent glucose-lowering properties when given by the oral route.