Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 9 de 9
Filtrar
Mais filtros










Intervalo de ano de publicação
1.
PLoS Negl Trop Dis ; 4(6): e711, 2010 Jun 15.
Artigo em Inglês | MEDLINE | ID: mdl-20559542

RESUMO

BACKGROUND: Outbreaks of orally transmitted Trypanosoma cruzi continue to be reported in Brazil and are associated with a high mortality rate, mainly due to myocarditis. METHODS: This study is a detailed report on the disease progression of acute Chagas disease in 13 patients who were infected during two micro-outbreaks in two northeastern Brazilian towns. Clinical outcomes as well as EKG and ECHO results are described, both before and after benznidazole treatment. RESULTS: Fever and dyspnea were the most frequent symptoms observed. Other clinical findings included myalgia, periorbital edema, headache and systolic murmur. Two patients died of cardiac failure before receiving benznidazole treatment. EKG and ECHO findings frequently showed a disturbance in ventricular repolarization and pericardial effusion. Ventricular dysfunction (ejection fraction <55%) was present in 27.3% of patients. After treatment, EKG readings normalized in 91.7% of patients. Ventricular repolarization abnormalities persisted in 50% of the patients, while sinus bradycardia was observed in 18%. The systolic ejection fraction normalized in two out of three patients with initially depressed ventricular function, while pericardial effusion disappeared. CONCLUSIONS: Myocarditis is frequently found and potentially severe in patients with acute Chagas disease. Benznidazole treatment may improve clinical symptoms, as well as EKG and ECHO findings.


Assuntos
Doença de Chagas/tratamento farmacológico , Surtos de Doenças , Doença Aguda , Adolescente , Adulto , Brasil/epidemiologia , Doença de Chagas/diagnóstico , Doença de Chagas/epidemiologia , Doença de Chagas/transmissão , Criança , Ecocardiografia Doppler , Eletrocardiografia , Feminino , Humanos , Masculino , Nitroimidazóis/uso terapêutico , Radiografia Torácica , Resultado do Tratamento , Tripanossomicidas/uso terapêutico , Trypanosoma cruzi/isolamento & purificação
2.
Arq Bras Cardiol ; 94(5): e59-61, e122-4, 2010 May.
Artigo em Inglês, Português | MEDLINE | ID: mdl-20549027

RESUMO

The present case reports on a patient presenting the cardiac form of Chagas disease, with left ventricular dysfunction and second-degree atrioventricular block Mobitz type II, associated with several syncope episodes. The patient underwent a double-chamber definitive artificial pacemaker implant. One year after the implant, the displacement of the atrial electrode was diagnosed and the patient was submitted to re-implantation of the atrial electrode. Two years after the first surgical procedure, the patient presented dyspnea on exertion. The physical evaluation included an echocardiogram, which detected the presence of a foreign body with metallic characteristics in the left cardiac chambers, consistent with that of an ectopic pacemaker electrode.


Assuntos
Cardiomiopatia Chagásica/terapia , Eletrodos Implantados/efeitos adversos , Migração de Corpo Estranho/diagnóstico por imagem , Marca-Passo Artificial/efeitos adversos , Adulto , Bloqueio Atrioventricular/terapia , Cardiomiopatia Chagásica/diagnóstico por imagem , Humanos , Masculino , Reoperação/efeitos adversos , Ultrassonografia , Disfunção Ventricular Esquerda/etiologia
3.
Arq. bras. cardiol ; 94(5): e122-e124, maio 2010. ilus
Artigo em Inglês, Português | LILACS | ID: lil-548099

RESUMO

Apresentamos o caso de um paciente portador da forma cardíaca da doença de Chagas com disfunção ventricular esquerda e bloqueio atrioventricular de 2º grau Mobitz II, associados a vários episódios de síncope. Foi submetido a implante de marcapasso artificial definitivo dupla câmara. Após um ano do implante foi diagnosticado deslocamento de eletrodo atrial, sendo submetido a reimplante de eletrodo atrial. Após dois anos do primeiro procedimento cirúrgico, apresentava dispneia aos grandes esforços. Durante a avaliação, foi solicitado ecocardiograma, que detectou a presença de corpo estranho de características metálicas em câmaras cardíacas esquerdas, consistente com eletrodo de marcapasso ectópico.


The present case reports on a patient presenting the cardiac form of Chagas disease, with left ventricular dysfunction and second-degree atrioventricular block Mobitz type II, associated with several syncope episodes. The patient underwent a double-chamber definitive artificial pacemaker implant. One year after the implant, the displacement of the atrial electrode was diagnosed and the patient was submitted to re-implantation of the atrial electrode. Two years after the first surgical procedure, the patient presented dyspnea on exertion. The physical evaluation included an echocardiogram, which detected the presence of a foreign body with metallic characteristics in the left cardiac chambers, consistent with that of an ectopic pacemaker electrode.


Assuntos
Adulto , Humanos , Masculino , Cardiomiopatia Chagásica/terapia , Eletrodos Implantados/efeitos adversos , Migração de Corpo Estranho , Marca-Passo Artificial/efeitos adversos , Bloqueio Atrioventricular/terapia , Cardiomiopatia Chagásica , Reoperação/efeitos adversos , Disfunção Ventricular Esquerda/etiologia
4.
Arq Bras Cardiol ; 81(4): 414-6, 411-3, 2003 Oct.
Artigo em Inglês, Português | MEDLINE | ID: mdl-14666283

RESUMO

OBJECTIVE: To determine the frequency of encephalic infarction and its contribution to lethality in patients with Chagas' disease and heart failure. METHODS: Medical records and autopsy reports of patients with Chagas' disease complicated by heart failure, who died at the Professor Edgar Santos Hospital of the Federal University of Bahia in the past 45 years were retrospectively analyzed. Data comprised information regarding the clinical history on hospital admission, complementary and anatomicopathological examinations, including the presence of encephalic infarction, the impaired region, and the cause of death. RESULTS: Of the 5,447 autopsies performed, 524 were in patients with heart failure due to Chagas' disease. The mean age was 45.7 years, and 51 (63%) patients were of the male sex. The frequency of encephalic infarction was 17.5%, corresponding to 92 events in 92 individuals, 82 (15.8%) of which involved the brain, 8 (1.5%) involved the cerebellum, and 2 (0.4%) involved the hypophysis. CONCLUSION: Cerebral infarction has been a frequent finding in autopsies of chagasic patients with heart failure, and it has been an important cause of death in our region. The presence of cerebral infarction and its complications have been associated with death in 52% of the cases studied.


Assuntos
Infarto Cerebral/complicações , Cardiomiopatia Chagásica/complicações , Insuficiência Cardíaca/complicações , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Brasil/epidemiologia , Causas de Morte , Infarto Cerebral/mortalidade , Infarto Cerebral/patologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Prevalência , Estudos Retrospectivos , Fatores de Risco
7.
Arq. bras. cardiol ; 81(4): 411-416, out. 2003. tab
Artigo em Inglês, Português | LILACS | ID: lil-349333

RESUMO

OBJECTIVE: To determine the frequency of encephalic infarction and its contribution to lethality in patients with Chagas' disease and heart failure. METHODS: Medical records and autopsy reports of patients with Chagas' disease complicated by heart failure, who died at the Professor Edgar Santos Hospital of the Federal University of Bahia in the past 45 years were retrospectively analyzed. Data comprised information regarding the clinical history on hospital admission, complementary and anatomicopathological examinations, including the presence of encephalic infarction, the impaired region, and the cause of death. RESULTS: Of the 5,447 autopsies performed, 524 were in patients with heart failure due to Chagas' disease. The mean age was 45.7 years, and 51 (63 percent) patients were of the male sex. The frequency of encephalic infarction was 17.5 percent, corresponding to 92 events in 92 individuals, 82 (15.8 percent) of which involved the brain, 8 (1.5 percent) involved the cerebellum, and 2 (0.4 percent) involved the hypophysis. CONCLUSION: Cerebral infarction has been a frequent finding in autopsies of chagasic patients with heart failure, and it has been an important cause of death in our region. The presence of cerebral infarction and its complications have been associated with death in 52 percent of the cases studied


Assuntos
Adolescente , Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Infarto Cerebral , Cardiomiopatia Chagásica , Insuficiência Cardíaca , Idoso de 80 Anos ou mais , Brasil , Causas de Morte , Infarto Cerebral , Prevalência , Estudos Retrospectivos , Fatores de Risco
8.
Arq Bras Cardiol ; 78(5): 441-3, 2002 May.
Artigo em Inglês | MEDLINE | ID: mdl-12045842

RESUMO

OBJECTIVE: The aim of this paper is to describe the prevalence of T. Cruzi infection in patients of from Mulungu do Morro, a rural tropical region of Northeastern Brazil. METHODS: A cross-sectional study was performed. After randomly selecting samples of the population, and obtaining their consents, patients completed pretested epidemiological and clinical questionnaires. Serum samples from all patients were collected and screened for the presence of T. cruzi antibodies. RESULTS: Of 694 patients examined, 174 patients (25.1%) tested had a positive serology for Chagas' disease. Of the study population, 341 patients were male with 27% Chagas' disease prevalence, without a statistical difference. Illiteracy was the only variable related to T. cruzi infection in our population. CONCLUSION: In conclusion, our study points to the high prevalence of Chagas' disease among patients in Mulungu do Morro, suggesting that this region has a high frequency of infection and probably active vectorial transmission.


Assuntos
Doença de Chagas/epidemiologia , Adolescente , Adulto , Brasil/epidemiologia , Criança , Pré-Escolar , Estudos Transversais , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Pessoa de Meia-Idade , Prevalência , População Rural/estatística & dados numéricos , Estudos Soroepidemiológicos , Fatores Socioeconômicos , População Urbana/estatística & dados numéricos
9.
Arq. bras. cardiol ; 78(5): 441-443, May 2002. graf
Artigo em Inglês | LILACS | ID: lil-314548

RESUMO

OBJECTIVE - The aim of this paper is to describe the prevalence of T. Cruzi infection in patients of from Mulungu do Morro, a rural tropical region of Northeastern Brazil. METHODS - A cross-sectional study was performed. After randomly selecting samples of the population, and obtaining their consents , patients completed pretested epidemiological and clinical questionnaires. Serum samples from all patients were collected and screened for the presence of T. cruzi antibodies. RESULTS - Of 694 patients examined, 174 patients (25.1 percent) tested had a positive serology for Chagas' disease. Of the study population, 341 patients were male with 27 percent Chagas' disease prevalence, without a statistical difference. Illiteracy was the only variable related to T. cruzi infection in our population. CONCLUSION - In conclusion, our study points to the high prevalence of Chagas' disease among patients in Mulungu do Morro, suggesting that this region has a high frequency of infection and probably active vectorial transmission


Assuntos
Humanos , Masculino , Feminino , Recém-Nascido , Lactente , Pré-Escolar , Criança , Adolescente , Adulto , Pessoa de Meia-Idade , Brasil , Doença de Chagas , Estudos Transversais , Prevalência , População Rural , Estudos Soroepidemiológicos , Fatores Socioeconômicos , População Urbana
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...