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Artigo em Inglês | MEDLINE | ID: mdl-12824729

RESUMO

The aim of this study was to determine the efficiency of labyrinth anesthesia - the intratympanic instillation of lidocaine--in the treatment of Ménière's disease and to recall a forgotten method. Twenty-four patients (15 male, 9 female), aged from 19.7 to 80.6 years (mean: 47.8 years) with the clinical diagnosis of unilateral Ménière's disease who underwent labyrinth anesthesia in our department were included in this retrospective study. After local anesthesia of the tympanic membrane, a solution of 4% lidocaine and furfuryladenine (Kinetin) was instilled into the tympanic cavity. Patient records, a questionnaire and a physical examination were used to evaluate vertigo control, hearing loss, tinnitus, and quality of life according to the AAO-HNS criteria before and after surgery. Postoperatively, 87.5% of patients reported at least a noticeable decrease of vestibular symptoms, 66.7% of these patients were free of attacks for an average of 26.5 months. Postoperative hearing was the same or even improved in 87.5% of our patients. Tinnitus was not affected in any individual. Based on the findings presented herein, we consider labyrinth anesthesia a practicable and, due to its safety, highly recommendable therapeutic option for patients suffering from Ménière's disease.


Assuntos
Adenina/análogos & derivados , Adenina/uso terapêutico , Anestésicos Locais/uso terapêutico , Orelha Interna/efeitos dos fármacos , Doença de Meniere/tratamento farmacológico , Adenina/administração & dosagem , Adulto , Idoso , Idoso de 80 Anos ou mais , Anestésicos Locais/administração & dosagem , Feminino , Perda Auditiva/etiologia , Humanos , Instilação de Medicamentos , Cinetina , Lidocaína/uso terapêutico , Masculino , Prontuários Médicos , Doença de Meniere/complicações , Doença de Meniere/fisiopatologia , Pessoa de Meia-Idade , Qualidade de Vida , Estudos Retrospectivos , Inquéritos e Questionários , Zumbido/etiologia , Resultado do Tratamento , Vertigem/etiologia
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