Recomendaciones nutricionales para pacientes hospitalizados con infección respiratoria grave (IRAG) sospechosa o confirmada por COVID-19 / Nutritional recommendations for hospitalized patients with severe respiratory infection (SARS) suspected or confirmed by COVID-19

Durante estas tres décadas del cuidado continuo de pacientes hospitalizados hemos reconocido la fisiopa-tología de la respuesta metabólica al estrés y la afectación de los enfermos desde la activación molecular de la sepsis, hasta el compromiso hemodinámico y neurológico del shock, ofreciendo soporte nutricional para obtener mejores resultados para la salud y la vida de nuestros pacientes, mediante recomendaciones que han sido comprobadas en poblaciones heterogéneas con diversas presentaciones en la práctica clínica. En esta revisión de la literatura proponemos sugerencias sobre la intervención nutricional en el paciente con SARS-CoV2 o COVID-19

During last three decades of continuous care of hospitalized patients, we have recognized the pathophysiology of the metabolic response to stress and the involvement of patients, from the molecular activation of sepsis to the hemodynamic and neurological involvement of shock, offering nutritional support to obtain better results for the health and life of our patients, through recommendations that have been verified in heterogeneous populations with different presentations in clinical practice. In this literature review we propose suggestions on nutritional intervention in patients with SARS-CoV2 or COVID-19

Gastric mixed adenoneuroendocrine carcinoma case report.

Mixed adenoneuroendocrine carcinomas are rare tumors that contain both an exocrine and an endocrine component. Since the latest classification by the World Health Organization and with the aid of immunostaining, more mixed adenoneuroendocrine carcinomas are now identified and diagnosed. Nonetheless, our knowledge of these tumors is still limited, notably concerning gastric variants, as the cases reported in the literature are very limited. The clinical and surgical treatment, including the chemotherapy schemes, the prognosis, and recurrence still represent challenges for the medical teams. We present the case of a 62-year-old woman. After an upper endoscopy revealed multiple polyps and a low-grade neuroendocrine tumor, a D2 radical gastrectomy was performed. A low output esophageal anastomotic leak was discovered in the postoperative period and successfully managed. Pathology revealed a gastric mixed adenoneuroendocrine carcinoma, the first case of this kind reported in Ecuador. Patient is doing well and under constant surveillance up until her 13th postoperative month.