Transposición pene-escrotal completa: diagnóstico prenatal / Complete penoscrotal transposition. Prenatal diagnosis

Presentamos un caso de diagnóstico prenatal de transposición pene-escrotal completa a la semana 20 de gestación. La exploración sistemática de todos los órganos, incluidos los genitales, posibilitan el diagnóstico de estas raras e infrecuentes malformaciones (AU)

We report a case of prenatal diagnosis of complete penoscrotal transposition in a fetus at 20 weeks of gestation. Systematic exploration of all the organs, including the genitals, allowed the diagnosis of these rare malformations (AU)

Pregnancy outcome in patients treated with cervical conization for cervical intraepithelial neoplasia.

OBJECTIVE: To examine the causal contribution of conization to premature delivery. METHODS: This was a retrospective, case-control, multicenter study of women who underwent conization in 5 hospitals in the Basque Country (Spain) from 1998 to 2007. Three study groups were established: group A, post-conization infant deliveries; control group B, pre-conization infant deliveries; and control group C, infant deliveries without conization. RESULTS: Comparing group A with group C, there was a higher rate of preterm delivery before 35 weeks (5.3% versus 1.6%), a lower mean birth weight (3156.2g versus 3328.5 g), and a greater prevalence of infants under 2500 g (10.6% versus 3.7%). There were no significant differences between group A and group B: preterm delivery before 35 weeks (5.3% versus 4.8%), mean birth weight (3156.2g versus 3119.4 g), and prevalence of infants under 2500 g (10.6% versus 10.6%). CONCLUSION: Pregnancy in women post-conization was associated with a risk of preterm delivery. However, there were no significant differences between women who underwent conization before and those who underwent conization after delivery. Cervical conization does not necessarily increase the risk of preterm delivery in subsequent pregnancy. Conization should be considered an indicator of such risk because it is associated with pregnancy complications arising from socio-epidemiologic factors present in women requiring conization that are also present in women who have premature delivery.

Embarazo gemelar con feto sano y mola completa como origen de enfermedad trofoblástica gestacional persistente: caso clínico / Twin pregnancy with a healthy foetus and a complete hydatidiform mole as a cause of persistent gestational trophoblastic disease

Describimos y analizamos el caso de una gestación múltiple bicigótica, consistente en un feto genotípica y morfológicamente sano junto a una mola hidatiforme completa, que desembocó en un parto prematuro en el segundo trimestre debido a complicaciones hipertensivas maternas. Tras la evacuación tanto del producto fetal como del tejido molar, la paciente desarrolló enfermedad trofoblástica gestacional persistente. Hemos querido centrar el caso en torno a esta última patología, y abordar los casos en que la enfermedad se presenta en un embarazo gemelar y exponer el curso diagnóstico y el posterior manejo médico dela fase persistente de la enfermedad trofoblástica gestacional (AU)

We describe and analyse the case of a multipledizy gotic pregnancy, formed by a genotypically and morphologically healthy foetus with acomplete hydatidi form mole that ended in apreterm birth in the 2nd trimester due tomaternal hypertension complications; after the evacuation of both foetus and the molar tissue, the patient developed a post-gestational Trophoblastic Neoplastic disease. We would liketo focus on this pathology, looking at cases where the disease occurs in a twin gestation, explaining the diagnostic procedure and subsequent medical management of the persistent phase of gestational trophoblastic disease (AU)