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Diagn Microbiol Infect Dis ; 57(4): 367-72, 2007 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-17141451

RESUMO

We have studied 912 patients with brucellosis. Of these, 631 (69.2%) were male and 48 had epididymo-orchitis, giving an incidence of epididymo-orchitis of 7.6%. The duration of symptoms before diagnosis was 52.5 +/- 70 days. All the patients had fever, swelling, and scrotal pain, but only 2 (4.2%) reported urinary symptoms. Seven patients (14.5%) had leukocyte figures above 11 x 10(9)/L, and urine analysis was normal in 69% of the patients. Blood cultures were positive in 65.8% of cases. A total of 33 patients (68.8%) received a combination of doxycycline plus streptomycin and 13 (27.1%) doxycycline plus rifampin. The overall percentage of failure or relapse was 8.8%: 7.1% in the doxycycline plus streptomycin group and 20% in the doxycycline plus rifampin group. None of the patients required surgery. Pending clinical trials to confirm the results, conservative management with a combination of doxycycline for 2 months and streptomycin for 14 to 21 days appears to be adequate and could avoid unnecessary orchiectomy.


Assuntos
Antibacterianos/uso terapêutico , Brucella melitensis , Brucelose , Epididimite , Orquite , Adolescente , Adulto , Idoso , Brucella melitensis/isolamento & purificação , Brucella melitensis/patogenicidade , Brucelose/diagnóstico , Brucelose/tratamento farmacológico , Brucelose/microbiologia , Brucelose/patologia , Doxiciclina/uso terapêutico , Quimioterapia Combinada , Epididimite/diagnóstico , Epididimite/tratamento farmacológico , Epididimite/microbiologia , Epididimite/patologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Orquite/diagnóstico , Orquite/tratamento farmacológico , Orquite/microbiologia , Orquite/patologia , Estreptomicina/uso terapêutico , Resultado do Tratamento
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