[PREVENTION OF BLEEDING FROM ESOPHAGEAL VARICES IN CIRRHOSIS].

Aim: The aim was to improved results of treatment of patients with threatened or held bleeding from esophageal varices on the background of liver cirrhosis. Materials and Methods: The analysis of the survey results and endoscopic treatment of 40 patients with liver cirrhosis complicated by threatened or held bleeding from esophageal varices. The effectiveness of the treatment was assessed by the dynamics of recourse degree esophageal varices, presence and character of postoperative complications and mortality. Results: Application of endoscopic ligation as primary and secondary prevention of bleeding from esophageal varices can improve the immediate and long-term results of treatment of patients with liver cirrhosis complicated by portal hypertension. Prevention of bleeding from esophageal varices is a dynamic endomonitoringe supplemented with repeated courses of endoscopic ligation.

[FUNCTIONAL AND CLINICAL DISORDERS OF THE LUNG IN PATIENTS WITH CIRRHOSIS AND THEIR DYNAMICS IN OPERATIONS TUNNELING LIVER].

Aim: Aim. To evaluate lung function in patients with liver cirrhosis of the liver with conservative therapy and surgery tunneling liver. Materials and methods: The study involved 55 patients with liver cirrhosis with portal hypertension. Patients were randomized into 2 groups. In the first group (n = 40) patients received medication. Patients of the second group (n = 15) was performed tunneling liver shunt operation. Results: In patients with liver cirrhosis observed clinical and functional remodeling of the lung appears shortness of breath, coughing, wheezing, and restrictive ventilatory disorders. Conclusions: In patients with cirrhosis of the liver after tunneling is observed normalization of lung ventilation. After conservative treatment reliable normalization of lung function occurs.

[Radiofrequency thermal ablation and its comlications in complex treatment of patients with liver cancer].

An analysis of efficacy of radiofrequency ablation (RFA) is presented in this article in 55 patients with liver cancer (82 interventions). According to the data of ultrasound investigations and computer tomography taken after 12 months from the first procedure, there weren't noted the growth of foci, which were subjected to RFA. Recurrent sessions using RFA were carried out on liver tumors in 6 patients after 3-11 months because of big size of primary lesion or newly revealed liver metastases. The cumulative one-year survival consisted of 88,2+/-7,9%, two-year survival - 68,0+/-14,1%.

[Principles of treatment of nonparasitic cysts of the liver].

A comparative investigation of different methods of treatment of nonparasitic cysts of the liver was carried out in 104 patients aged from 21 through 74 years with sizes of the cysts from 6 to 21 cm in diameter, divided into three groups. The first group included 50 patients who were subjected to open operations (segmentectomy, bisegmentectomy, fenestration of the cysts with treatment of the residual inner lining with ethanol, diathermocoagulation or cryodestruction). Laparoscopic fenestration and chemical or thermal treatment of the cysts were used in the second group of 29 patients, in the third group consisting of 25 patients a puncture-aspiration method was used under sonographic control. An analysis of the results showed advantages of laparoscopic and puncture methods that gave good immediate and long-term results, less number of postoperative complications and shorter periods of rehabilitation of the patients.

[Means of reducing blood loss and volume of the used transfused media in operative treatment of burn lesions of the liver]. / Puti snizheniia velichiny krovopoteri i ob"ema ispol'zuemykh transfuzionnykh sred pri operativnom lechenii ochagovykh porazhenii pecheni.

An experience with surgical treatment of 77 patients with focal lesions of the liver is described. The patients were divided into two groups. In the main group (42 patients) the treatment-and-prophylactic method was used including acute isovolemic and hypervolemic hemodilution, preliminary preparation of autoblood, isolation and ligation of the vascular-secretory elements, the application for local hemostasis with Takhokomb of "Tissucol", gelatinous sponge with gentamycin. In the group of comparison the compression of the hepatoduodenal ligament, isolation of the vascular-secretory elements by digitoclasia method, suturing the liver stump with polysorb were used in resection of the liver. The strategy used in the main group allowed to reduce the volume of blood loss, to lessen the number of doses of the transfused donor blood, to diminish the number of postoperative complications by 30.5%. The used complex is effective, simple and is not expensive.

[Laboratory and clinical study of therapeutic efficacy of medicinal films for surgical procedures]. / Laboratorno-klinicheskoe issledovanie terapevticheskoi éffektivnosti lekarstvennykh plenok khirurgicheskogo naznacheniia.

An analysis of the experimental data showed that anesthetic medicinal films (AMFs) offer an effective medicinal form for the treatment of suppurative inflammatory disorders(SIDs) of soft tissues. The results of preclinical experiments with AMFs showed evidence of anesthetic, antimicrobial, and hemostatic effects. The therapeutic effect was established in the course of clinical investigations and confirmed by the results of cytological, histological, morphological, and bacteriological testing. The experimental data indicate that AMF application offers a promising means of SID treatment. Further development of this medicinal form must lead to an increase in the therapeutic efficacy, decrease the drug dose, and reduce the probability of side effects during the treatment of SIDs in soft tissues of various localization.