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Ir J Med Sci ; 182(4): 697-701, 2013 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-23645548

RESUMO

AIMS: To study the nature of the tumours managed in the Irish population. METHODS: This audit research was completed via a retrospective medical review on 200 patients with CNS tumours managed in a tertiary care centre between 2008 and 2009. RESULTS: The mean age was 53 years. The male:female ratio was 2:1. The majority were glioblastomas and astrocytomas. Grade IV tumours were predominant (65.5 %). Headaches (37 %), motor weakness (32 %) and seizures (25.5 %) were the highest presentations. The commonest sites affected were the left parietal and left temporal lobes. There were 17.5 % operative morbidities with motor weakness (22.9 %), seizure (14.3 %) and thrombo-embolism (14.3 %) dominating and significant association to surgical radicality (p = 0.041). 3.5 % operative mortalities were reported. 52.5 and 62.5 % of patients received adjuvant chemotherapy and radiotherapy, respectively. CONCLUSIONS: Patients with CNS tumours typically had multiple presentations. More extensive surgical resection was associated with higher postoperative morbidities (p = 0.041). The 30-day postoperative morbidity (17.5 %) and mortality (3.5 %) were concordant with the currently available literature.


Assuntos
Astrocitoma/cirurgia , Neoplasias do Sistema Nervoso Central/cirurgia , Glioblastoma/cirurgia , Procedimentos Neurocirúrgicos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Astrocitoma/complicações , Astrocitoma/mortalidade , Neoplasias do Sistema Nervoso Central/complicações , Neoplasias do Sistema Nervoso Central/mortalidade , Quimioterapia Adjuvante , Criança , Pré-Escolar , Feminino , Glioblastoma/complicações , Glioblastoma/mortalidade , Cefaleia/etiologia , Humanos , Lactente , Irlanda , Masculino , Auditoria Médica , Pessoa de Meia-Idade , Doença dos Neurônios Motores/etiologia , Gradação de Tumores , Procedimentos Neurocirúrgicos/efeitos adversos , Procedimentos Neurocirúrgicos/mortalidade , Radioterapia Adjuvante , Estudos Retrospectivos , Convulsões/etiologia , Centros de Atenção Terciária , Tromboembolia/etiologia , Resultado do Tratamento , Adulto Jovem
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