RESUMO
OBJECTIVE: To evaluate normal patterns of enhancement of signal intensity in and about the atlantoaxial joints following intravenous administration of a gadolinium-containing contrast agent. METHODS AND MATERIAL: Fat-suppressed axial T1 weighted SE images were obtained in 12 patients without evidence of inflammmatory arthritis before and immediately after intravenous administration of a gadolinium-containing contrast agent. Patterns of enhancement of signal intensity in and about the atlantoaxial joints were evaluated qualitatively. RESULTS: Four different MR imaging patterns were observed: no enhancement of signal intensity, enhancement in the form of a single punctate region, enhancement in a confluent pattern, and bandlike enhancement. CONCLUSION: Enhancement occurs around the odontoid process in patients without evidence of rheumatoid arthritis (RA). The dividing line between early synovitis and normal enhancement seems broader than expected. The reasons remain unclear and warant further studies.
Assuntos
Articulação Atlantoaxial/anatomia & histologia , Meios de Contraste/administração & dosagem , Gadolínio DTPA/administração & dosagem , Imageamento por Ressonância Magnética , Adulto , Feminino , Humanos , Injeções Intravenosas , Masculino , Pessoa de Meia-IdadeRESUMO
Linear nevus sebaceous syndrome is a rare neurocutaneous syndrome in which associated radiographic findings of the peripheral skeletal system are uncommon. We report a follow-up study of a patient with mainly unilateral changes of the skeletal system involving the thorax and the right arm and leg.
Assuntos
Anormalidades Múltiplas , Hamartoma/diagnóstico por imagem , Nevo/diagnóstico por imagem , Glândulas Sebáceas , Neoplasias Cutâneas/diagnóstico por imagem , Anormalidades Múltiplas/diagnóstico por imagem , Anormalidades Múltiplas/patologia , Diagnóstico Diferencial , Traumatismos dos Dedos/diagnóstico por imagem , Dedos/anormalidades , Dedos/diagnóstico por imagem , Seguimentos , Fraturas Espontâneas/diagnóstico por imagem , Hamartoma/patologia , Humanos , Recém-Nascido , Masculino , Nevo/patologia , Radiografia , Costelas/anormalidades , Costelas/diagnóstico por imagem , Costelas/lesões , Dermatopatias/diagnóstico por imagem , Dermatopatias/patologia , Neoplasias Cutâneas/patologia , SíndromeRESUMO
Recently, human leukocyte elastase has been detected in human eosinophils. Reinvestigating these findings, 2.5 pg active human leukocyte elastase (E.C. 3.4.21.37) were found per neutrophil isolated from peripheral blood, whereas the elastase activity of eosinophil preparations was linearly correlated with the content of contaminating neutrophils. Also spontaneous or stimulated release of active elastase was absent in eosinophils. By immunohistochemistry no elastase immunoreactivity could be demonstrated in human eosinophils. Therefore, we conclude that human eosinophils do not contain considerable amounts of human leukocyte elastase.