RESUMO
BACKGROUND: Abdominal tuberculosis is a common complication of pulmonary tuberculosis. With the rising incidence of HIV, tuberculosis has become a major public health problem particularly in developing countries. METHODS: This is a retrospective study involving patients whose surgical specimens were processed at the central histopathology laboratory of the Ahmadu Bello University Teaching Hospital (ABUTH) Zaria--Nigeria, between January 1975 to December 2006. RESULTS: There were 68 males and 49 females, aged 12-70 years (mean 28.6 yrs 11 yrs). While paroxysmal dry cough was present in about 20 patients, abdominal pain and distension were very common. Concomitant pulmonary tuberculosis was confirmed in 15 patients (14%). The findings at Surgery in 66 patients are presented in fig. 2. Multiple deposits on the peritoneum and omentum were the commonest findings (48.7% and 26.2%) respectively CONCLUSION: Abdominal tuberculosis is not uncommon and there is need to establish an early less invasive diagnostic protocol.
Assuntos
Dor Abdominal/etiologia , Peritonite Tuberculosa/complicações , Tuberculose Gastrointestinal/complicações , Abdome , Dor Abdominal/cirurgia , Adolescente , Adulto , Idoso , Antituberculosos/uso terapêutico , Biópsia , Criança , Feminino , Hospitais de Ensino , Humanos , Incidência , Achados Incidentais , Laparotomia , Masculino , Pessoa de Meia-Idade , Nigéria/epidemiologia , Peritonite Tuberculosa/tratamento farmacológico , Peritonite Tuberculosa/epidemiologia , Peritonite Tuberculosa/cirurgia , Estudos Retrospectivos , Tuberculose Gastrointestinal/tratamento farmacológico , Tuberculose Gastrointestinal/epidemiologia , Tuberculose Gastrointestinal/cirurgia , Adulto JovemRESUMO
Background: Abdominal tuberculosis is a common complication of pulmonary tuberculosis. With the rising incidence of HIV; tuberculosis has become a major public health problem particularly in developing countries. Methods: This is a retrospective study involving patients whose surgical specimens were processed at the central histopathology laboratory of the Ahmadu Bello University Teaching Hospital (ABUTH) Zaria - Nigeria; between January1975 to December 2006. Results: There were 68 males and 49 females; aged 12-70 years (mean 28.6yrs 11yrs). While paroxysmal dry cough was present in about 20 patients; abdominal pain and distension were very common. Concomitant pulmonary tuberculosis was confirmed in 15 patients (14). The findings at Surgery in 66 patients are presented in fig.2. Multiple deposits on the peritoneum and momentum were the commonest findings (48.7and 26.2) respectively. Conclusion: Abdominal tuberculosis is not uncommon and there is need to establish an early less invasive diagnostic protocol
Assuntos
Hospitais , Incidência , Ensino , TuberculoseRESUMO
This study analyzed the antidiabetic properties of an ethanol extract of the stem bark of Psidium guajava, an indigenous medicinal plant used to control diabetes in Indian System of Medicine. The anti-hyperglycaemic activity of this plant on blood glucose levels of normal, normal glucose loaded (OGTT) and alloxan-induced hyperglycaemic rats was evaluated. The results showed that ethanol stem bark extract exhibited statistically significant hypoglycaemic activity in alloxan-induced hyperglycaemic rats but was devoid of significant hypoglycaemic effect in normal and normal glucose loaded rats (OGTT).
Assuntos
Hipoglicemiantes/farmacologia , Psidium/química , Animais , Glicemia/metabolismo , Diabetes Mellitus Experimental/sangue , Diabetes Mellitus Experimental/tratamento farmacológico , Etanol , Feminino , Gliclazida/farmacologia , Teste de Tolerância a Glucose , Masculino , Casca de Planta/química , Extratos Vegetais/farmacologia , Ratos , Ratos Wistar , SolventesRESUMO
An aqueous and alcoholic extract of the roots of Aralia cachemirica (Araliaceae) were evaluated for hypoglycemic activity in normal fasted and glucose induced hyperglycemic rats. The aqueous and alcoholic extracts at a dose of 250 mg/kg showed statistically significant (p < 0.01) hypoglycemic activity in glucose loaded animals however no effect was observed in normal fasted rats.
Assuntos
Aralia/química , Glicemia/metabolismo , Hipoglicemiantes/química , Hipoglicemiantes/farmacologia , Animais , Etanol , Jejum/metabolismo , Feminino , Glucose/farmacologia , Masculino , Medicina Tradicional Tibetana , Extratos Vegetais/análise , Raízes de Plantas/química , Ratos , Ratos Wistar , Solventes , ÁguaRESUMO
An aqueous extract of Pterocarpus marsupium wood was screened for hypoglycemic activity on alloxan-induced diabetic rats. During both acute and sub-acute tests, the water extract, at an oral dose of 250 mg/kg, showed statistically significant hypoglycemic activity.
Assuntos
Diabetes Mellitus Experimental/tratamento farmacológico , Hipoglicemiantes/farmacologia , Fitoterapia , Pterocarpus/química , Animais , Glicemia/metabolismo , Feminino , Insulina/metabolismo , Masculino , Pâncreas/efeitos dos fármacos , Pâncreas/metabolismo , Extratos Vegetais/farmacologia , Ratos , Ratos Wistar , Solventes , ÁguaRESUMO
A water extract of Psidium guajava leaves was screened for hypoglycemic activity on alloxan-induced diabetic rats. In both acute and sub-acute tests, the water extract, at an oral dose of 250 mg/kg, showed statistically significant hypoglycemic activity.
Assuntos
Diabetes Mellitus Experimental/tratamento farmacológico , Fitoterapia , Psidium/química , Animais , Glicemia/metabolismo , Feminino , Índia , Masculino , Pâncreas/efeitos dos fármacos , Extratos Vegetais/uso terapêutico , Ratos , Ratos WistarRESUMO
A new oleanene-type triterpene, named betuloleanolic acid acetate and fernane-type triterpenes, namely betufernanediol A and betufernanediol B (isomers) have been isolated from the stem bark of Betula pendula. Their structures have been established as olean-12-en-3beta-ylacetate-29-oic acid, fern-22(29)-en-3beta,12beta-diol and fem-22(29)-en-3alpha,12beta-diol, respectively, on the basis of spectral data analysis and chemical reactions.
