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1.
Annu Int Conf IEEE Eng Med Biol Soc ; 2018: 466-469, 2018 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-30440435

RESUMO

Chronic insomnia can significantly impair an individual's quality of life leading to a high societal cost. Unfortunately, limited automated tools exist that can assist clinicians in the timely detection of insomnia. In this paper, we propose a two stage approach to automatically detect insomnia from an overnight EEG recording. In the first stage we trained a sleep stage scoring model and an epoch-level insomnia detection model. Both models are deep neural network (DNN)- based which are fed by a set of temporal and spectral features derived from 2 EEG channels. In the second stage we computed two subject-level feature sets. One is computed using the output of the sleep stage scoring model and consists of the sleep stage ratios, the stage pair ratios and the stage transition ratios. The second feature set is derived from the output of the epoch-level insomnia detection model and represents the ratio of detected insomniac epochs in each stage and their average posterior probability. These features are then used to train a final binary classifier to classify each subject as control, i.e., with no sleep complaints, or insomniac. We compared 5 different binary classifiers, namely the linear discriminant analysis (LDA), the classification and regression trees (CART) and the support vector machine (SVM) with linear, Gaussian and sigmoid kernels. The system was evaluated against data collected from 115 participants, 61 control and 54 with insomnia, and achieved $F1$ score, sensitivity and specificity of 0.88, 84% and 91% respectively.


Assuntos
Eletroencefalografia , Redes Neurais de Computação , Distúrbios do Início e da Manutenção do Sono/diagnóstico , Adolescente , Adulto , Idoso , Análise Discriminante , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Distribuição Normal , Sensibilidade e Especificidade , Fases do Sono , Máquina de Vetores de Suporte , Adulto Jovem
2.
Annu Int Conf IEEE Eng Med Biol Soc ; 2017: 3749-3752, 2017 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-29060713

RESUMO

Sleep disorders are becoming increasingly prevalent in society. However most of the burgeoning research on automated sleep analysis has been in the realm of sleep stage classification with limited focus on accurately diagnosing these disorders. In this paper, we explore two different models to discriminate between control and insomnia patients using support vector machine (SVM) classifiers. We validated the models using data collected from 124 participants, 70 control and 54 with insomnia. The first model uses 57 features derived from two channels of EEG data and achieved an accuracy of 81%. The second model uses 15 features from each participant's hypnogram and achieved an accuracy of 74%. The impetus behind using these two models is to follow the clinician's diagnostic decision-making process where both the EEG signals and the hypnograms are used. These results demonstrate that there is potential for further experimentation and improvement of the predictive capability of the models to help in diagnosing sleep disorders like insomnia.


Assuntos
Distúrbios do Início e da Manutenção do Sono/diagnóstico , Humanos , Fases do Sono , Máquina de Vetores de Suporte
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