Adequately iodized salt is an important strategy to prevent iodine insufficiency in pregnant women living in Central Java, Indonesia.

Iodine is an essential micronutrient for cognitive development and growth. Optimal intakes are critical during pregnancy. We report the iodine status and thyroid function of pregnant women living in areas previously affected by severe iodine deficiency and in longstanding iodine sufficient areas in Java, Indonesia. This cross-sectional study was conducted in Magelang, Java, from July to November 2015, in four sub-districts; two previously affected by severe iodine deficiency (area 1) and two that were iodine-sufficient (area 2). Iodine intake was estimated using median urinary iodine concentration in spot samples and mean urinary iodine excretion in 3 x 24-hour samples, thyroid hormones (thyroid-stimulating hormone and free thyroxine) were measured in venous blood samples, and iodine content of household salt samples was estimated by titration. We recruited a total of 244 pregnant women, 123 in area 1 and 121 in area 2. Urinary iodine results suggested adequate habitual iodine intakes in both areas (median urinary iodine concentration in area 1: 222 µg/l (interquartile range 189, 276 µg/l), area 2: 264 µg/l (interquartile range 172, 284 µg/l), however, the risk of inadequate intakes increased with advancing trimester (Odds Ratio = 2.59 (95% CI 1.19-5.67) and 3.85 (95% CI 1.64-9.02) at second and third trimesters, respectively). Estimated prevalence of thyroid function disorders was generally low. Salt was iodized to approximately 40 ppm and foods rich in native iodine did not contribute significantly to dietary intakes. Adequately iodized salt continues to prevent iodine insufficiency in pregnant women living in areas previously affected by severe iodine deficiency in Java, Indonesia. Monitoring and surveillance, particularly in vulnerable groups, should be emphasized to ensure iodine sufficiency prevails.

Assesment of Thyroid Function and Its Association with Free Thyroxin Hormone among Pregnant Women in Areas with Previous History Iodine Deficiency in Magelang, Indonesia.

Iodine deficiency in pregnant woman can affect growth and development of fetus. People who live in an area that had affected by previous iodine deficiency may continuously affect by abnormal thyroid function. The aim of the study is to assess thyroid function, that was measured by the concentrations of thyroid stimulating hormone, and its relationships with free thyroxine (fT4) among pregnant women in the two different geographic areas with previous history of iodine deficiency in Magelang, Central Java, Indonesia. Cross-sectional study was conducted in two types of location (replete and non-replete area) in Magelang, Central Java, Indonesia. A total of 243 aged between 15-45 y old with no pregnancy complication from two different geographics areas of iodine replete and sufficient were include in study. Blood biochemical markers such as free thyroxine hormone and thyroid stimulating hormone were assessed by Elisa method. Median of fT4 in non-replete and replete area was 1.18 (0.63-3.5) ng/dL; 1.12 (0.37-1.95) ng/dL, respectively. Whilst, median of TSH in replete area was 1.27 (0.09-8.21) ng/dL and non replete area was 1.3 (0.01-8.67) ng/dL. Correlation between fT4 and TSH showed significat relationship in non-replete area, r=-0.39 (<0.05), but it was not significant in replete area, r=-0.08 (>0.05). In addition, scatter plot showed the relationship between fT4 and TSH levels pattern in the replete area more widespread. Pregnant womens who live in areas that had affected severe iodine deficiency intake may have abnormal thyroid function but it still euthyroid maintain by adequate iodine intake.

Pathway Analysis of Growth Faltering Pattern Based on Height for Age in Children Under Five in Indonesia Based on Indonesian National Health Survey 2013.

Growth failure has a severe impact on public health problems. Stunting is a particular growth failure contributing to the child mortality and morbidity of non-communicable diseases in adults. Objective: To analyze the determinants of growth failure patterns in children under five years in Indonesia. The further analysis was taken from 6,020 samples, based on the Indonesian National Health Survey (Riskesdas) 2013 (cross-sectional survey with a multistage cluster sampling method). Inclusion criteria are data that have completed records. The exclusion criteria were data having no outlier in anthropometric measurement. Nutrition status is analyzed using WHO AnthroPlus 2009. Data analysis is taken by path analysis in SPSS 21. The growth curve height for the under five-year children in Indonesia is less than the WHO growth standard. The mean height for age z-score (HAZ) has declined in linear patterns among the first five years of life. The determinant of growth is divided into two age groups. Overall, socioeconomic status has an indirect effect adjusted by both age and gender with r 0.10. In children <36 mo, the nutrition status of the mother has a direct and indirect effect on the birth nutrition status with r 0.17, while low birth weight, breastfeeding status, infectious disease, and immunization are the direct factor to HAZ score. In children aged 37-59 mo, infectious disease is a direct factor. Socioeconomic status, BMI of a mother, breastfeeding status, immunization, and infectious disease are the determinants of growth failure patterns in Indonesia.