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1.
Cureus ; 16(4): e59313, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38817527

RESUMO

We present a case of a woman in her 60s, with a history of a gastric sleeve resection, over 50% excess body weight loss, and subsequent severe gastroesophageal reflux disease refractory to maximal medical therapy, who underwent a conversion of a sleeve gastrectomy to a Roux-en-Y gastric bypass with hiatal hernia repair. On postoperative day five, she was evaluated at our emergency department for vomiting and inability to tolerate oral intake. Imaging revealed a large retrocardiac hiatal hernia and extraluminal contrast extravasation. She was taken to the operating room after resuscitation, where the gastric pouch and roux limb were found to have significant edema with recurrence of the hernia. This was able to be reduced and a frank perforation was found at the posterior aspect of the anastomosis. A covered metal stent was placed by the gastroenterologist and drains were left in place.  In the ICU, nasojejunal feeds were stopped given suspicion of backflow with persistent leak. A decision was made to remove the stent and place an endoluminal vacuum (endoscopic vacuum-assisted wound closure [EVAC]). After three subsequent vacuum-sponge changes, the perforation was found to have healed. Patient was tolerating a diet on discharge. This case is an example of a complication where a multidisciplinary approach to a difficult leak resulted in recovery with the use of EVAC. We believe this is a valuable tool to have in our armamentarium for difficult-to-manage leaks.

2.
Case Rep Dermatol ; 15(1): 202-216, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37928337

RESUMO

Poroid hidradenoma (PH) is a rare benign adnexal tumor of eccrine differentiation. It is the rarest of the four described variants of poroid neoplasms. PHs characteristically share a hybrid of the architectural features of the hidradenoma, namely, tumor cells are entirely intradermal with both solid and cystic components, and the cytologic characteristics of the poroid neoplasms, containing predominantly poroid and cuticular cells. Many published reports of PH since its original discovery in 1990 state that "very few" cases of PH can be found in the literature. Here, we have identified a total of 75 published accounts of PH, including the case presented here, as well as the associated patient demographics, lesion characteristics, treatment, and outcomes. We suggest that while uncommon, PH is likely not exceptionally rare and could be an underreported diagnosis.

3.
Surg Endosc ; 36(11): 8515-8519, 2022 11.
Artigo em Inglês | MEDLINE | ID: mdl-36042042

RESUMO

INTRODUCTION: Obesity is one of the leading public health concerns with over half a million Americans being classified as obese and almost two billion classified as overweight. This has an impact on overall health of the individual, with increased comorbidities and premature death, as well as increased economic cost. This study evaluates the weight loss of patients with limited societal support and resources cared for at a single bariatric center of excellence, The Center for Surgical Weight Control, in Cabell County, West Virginia. METHODS: Retrospective review of patients that have undergone either a Vertical Sleeve Gastrectomy (VSG) or a Roux-en-Y gastric bypass (RNYGB) between the years of 2017 and 2018 At the Center for Surgical Weight Control. Weight loss was evaluated at 6 months, 1 year, and 2 years. RESULTS: There were 290 patients between 2017 and 2018. On average, the VSG group lost 46% of excess body weight (EBW) at 6 months, 57% of EBW at 1 year, and 61% of EBW at 2 years. In the RNYGB group patients lost on average 54% of EBW at 6 months, 65% of EBW at 1 year, and 88% of EBW at 2 years. DISCUSSION: A loss of 5-15% of EBW can improve obesity-related comorbidities. These comorbidities include diabetes, hypertension, hyperlipidemia, gastroesophageal reflux disease, and obstructive sleep apnea. Improvement in these comorbidities not only benefits each patient individually, but will also help improve the effects on society as a whole. CONCLUSION: Obesity is a debilitating and deadly disease, thus makes it very important to address in order to reduce burden on both patients and society as a whole. There is an expected amount of weight loss a patient should have depending on the type of surgery they undergo. Our patients were successful at meeting and exceeding the expected percentage of EBW loss after both VSG and RNYGB.


Assuntos
Derivação Gástrica , Laparoscopia , Obesidade Mórbida , Humanos , Obesidade Mórbida/cirurgia , West Virginia/epidemiologia , Redução de Peso , Gastrectomia , Estudos Retrospectivos , Resultado do Tratamento
4.
Am Surg ; 88(5): 997-999, 2022 May.
Artigo em Inglês | MEDLINE | ID: mdl-34872387

RESUMO

The urachus is a remnant of the allantois. Failure to obliterate can result in one of four anomalies, urachal cyst being most common. Urachal cysts are relatively rare, especially in adults. This paper presents a patient with an umbilical hernia and a ruptured urachal cyst. A 39-year-old male presented with concern for umbilical hernia, but he also noted drainage. Computed tomography scan showed a urachal cyst and umbilical hernia. The urachal cyst was excised and umbilical hernia closed primarily. The incidence of an urachal cyst is unknown, but persists in roughly 2% of adults. Diagnosis is with ultrasound or CT scan. Management is excision due to risk of urachal carcinoma, which is present in over 50% of specimens. Review of literature did not reveal any other cases of a patient with both an urachal cyst and an umbilical hernia, thus making this case a unique presentation for this condition.


Assuntos
Hérnia Umbilical , Cisto do Úraco , Úraco , Adulto , Hérnia Umbilical/complicações , Hérnia Umbilical/diagnóstico , Hérnia Umbilical/cirurgia , Humanos , Masculino , Ruptura , Ultrassonografia , Cisto do Úraco/complicações , Cisto do Úraco/diagnóstico , Cisto do Úraco/cirurgia , Úraco/anormalidades , Úraco/patologia , Úraco/cirurgia
5.
Am Surg ; 88(5): 992-993, 2022 May.
Artigo em Inglês | MEDLINE | ID: mdl-34854772

RESUMO

In 2018, general surgery topped the number of robotic cases. Over 90% of residents participate, but only 65% of programs have a formal curriculum, and less than half track progress. Many are insufficient at training due to an observational role. This paper reviews Marshall University General Surgery Residency program's robotic curriculum, which started in 2018. The curriculum consists of a weekend course and simulations, enabling residents obtain certification. Residents participated in Intuitive's Resident Robotic Olympics with first place in 2019 and second and third place in 2020. For the 2021 year, the robotic curriculum was revised into phases based on year. Deadlines and forms help improve and track progress. It is important to develop a curriculum with a protocol for training, monitoring, and credentialing to ensure proficiency. Marshall University General Surgery robotic curriculum has been successful at improving robotic skill, enabling residents to obtain a robotic surgery certification upon graduation.


Assuntos
Cirurgia Geral , Internato e Residência , Procedimentos Cirúrgicos Robóticos , Robótica , Competência Clínica , Currículo , Educação de Pós-Graduação em Medicina/métodos , Cirurgia Geral/educação , Humanos , Procedimentos Cirúrgicos Robóticos/educação
6.
J Surg Res ; 256: 180-186, 2020 12.
Artigo em Inglês | MEDLINE | ID: mdl-32711173

RESUMO

BACKGROUND: Despite the increasing prevalence and severity of childhood obesity, the national utilization of adolescent bariatric surgery has plateaued. Concern about the perioperative safety of adolescent bariatric surgery has limited referrals and insurance coverage. The purpose of this study was to compare the 30-d complication rate of minimally invasive bariatric surgery in adolescents and adults. MATERIALS AND METHODS: The Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program 2015 data set was queried for primary minimally invasive bariatric procedures in adolescents and adults. Adolescents were defined as age 19 y or younger. Univariate analyses were performed to determine if there was an increased incidence of the adolescent 30-d complication rate as compared with adults. RESULTS: Of the cases who met inclusion criteria, 1076 (0.8%) were adolescents and 142,704 (99.2%) were adults. Laparoscopic sleeve gastrectomy was the most commonly performed procedure for both patient populations, although at a higher rate in adolescents (73.9% versus 68.8% in adults, P = 0 < 0.0001). The overall 30-d complication rate was comparable in adolescents and adults (6.3% versus 7.3%; P = 0.21) with similar rates of intervention, reoperation, readmission, and mortality. There was no significant difference in any specific perioperative complication class reported between adolescents and adults, except wound disruption (0.2% versus 0.0%, P < 0.0001) and postlaparoscopic sleeve gastrectomy coma >24 h (0.1% versus 0.0%, P < 0.0001). CONCLUSIONS: Bariatric surgery in adolescents shares a similar perioperative safety profile as found in adults. This data support the utilization and extension of adult criteria for bariatric surgery to adolescents with morbid obesity.


Assuntos
Cirurgia Bariátrica/efeitos adversos , Obesidade Mórbida/cirurgia , Obesidade Infantil/cirurgia , Complicações Pós-Operatórias/epidemiologia , Adolescente , Adulto , Fatores Etários , Feminino , Mortalidade Hospitalar , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Readmissão do Paciente/estatística & dados numéricos , Complicações Pós-Operatórias/etiologia , Reoperação/estatística & dados numéricos , Resultado do Tratamento , Estados Unidos/epidemiologia , Adulto Jovem
7.
Crit Care Res Pract ; 2020: 9719751, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32185080

RESUMO

OBJECTIVE: The objective of the study was to use an ultrasound-based numerical scoring system for assessment of intravascular fluid estimate (SAFE) and test its validity. METHODS: A prospective, observational study was carried out in the surgical intensive care unit (ICU) of an urban tertiary care teaching hospital. Patient's intravascular volume status was assessed using the standard methods of heart rate, blood pressure, central venous pressure, cardiac output, lactate and saturation of venous oxygen, and others. This was compared with assessment using bedside ultrasound evaluation of the cardiac function, inferior vena cava, lungs, and the internal jugular vein. Applying a numerical scoring system was evaluated by Fisher's exact testing and multinomial logistic model to predict the volume status based on ultrasound scores and the classification accuracy. RESULTS: 61 patients in the ICU were evaluated. 21 (34.4% of total) patients diagnosed with hypovolemia, and their ultrasound volume score was -4 in 14 (66.7%) patients, -3 in 5 (23.8%) patients, and 0 in 2 (9.5%) patients (p < 0.001). 18 (29.5% of total) patients diagnosed with euvolemia, and their ultrasound volume score was 0 in 11 (61.1%) patients, +1 in 4 (22.2%) patients, and -1 in 1 (5.6%) patient (p < 0.001). 18 (29.5% of total) patients diagnosed with euvolemia, and their ultrasound volume score was 0 in 11 (61.1%) patients, +1 in 4 (22.2%) patients, and -1 in 1 (5.6%) patient (p < 0.001). 18 (29.5% of total) patients diagnosed with euvolemia, and their ultrasound volume score was 0 in 11 (61.1%) patients, +1 in 4 (22.2%) patients, and -1 in 1 (5.6%) patient (p < 0.001). 18 (29.5% of total) patients diagnosed with euvolemia, and their ultrasound volume score was 0 in 11 (61.1%) patients, +1 in 4 (22.2%) patients, and -1 in 1 (5.6%) patient (. CONCLUSION: Using the SAFE scoring system to identify the IVV status in critically ill patients significantly correlates with the standard measures. A SAFE score of -4 to -2 more likely represents hypovolemia, -1 to +1 more likely represents euvolemia, and +2 to +4 more likely to be hypervolemia.

8.
Surg Obes Relat Dis ; 16(3): 397-405, 2020 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-31932204

RESUMO

BACKGROUND: There are limited data evaluating the role of robotics in revisional bariatric surgery (RBS) compared with laparoscopy. OBJECTIVE: The purpose of this study was to compare perioperative outcomes of laparoscopic and robotic RBS. SETTING: The Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP) database. METHODS: The 2015 to 2017 MBSAQIP database was queried for patients undergoing revisional robotic and laparoscopic sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB). Multivariate logistic regression was used to compare outcomes between robotic and laparoscopic approaches, adjusting for demographic characteristics, co-morbidities, and operative time. RESULTS: A total of 17,012 patients underwent revisional SG with 15,935 (93.7%) laparoscopic and 1077 (6.3%) robotic, and 12,442 patients underwent revisional RYGB with 11,212 (90.1%) laparoscopic and 1230 (9.9%) robotic. Overall morbidity was higher in robotic SG compared with laparoscopic SG (6.7% versus 4.5%; adjusted odds ratio 1.51; P < .01) which was not the case after adjustment for operative time. Robotic RYGB was associated with comparable overall morbidity to laparoscopic (9.3% versus 11.6%; adjusted odds ratio .83; P = .07) although respiratory complications, pneumonia, superficial surgical site infections, and postoperative bleeding were lower with robotic RYGB. The robotic approach with both procedures was associated with longer operative time (P < .01). Length of stay was longer in the robotic group for SG (P < .01) but was not different for RYGB (P = .91). CONCLUSIONS: Robotic RBS has an increased complication profile compared with the laparoscopic approach for SG and decreased for RYGB. Further analysis is needed regarding variability in surgeon technique and operative experience to determine what factors contribute to these differences.


Assuntos
Cirurgia Bariátrica , Derivação Gástrica , Laparoscopia , Obesidade Mórbida , Acreditação , Cirurgia Bariátrica/efeitos adversos , Gastrectomia/efeitos adversos , Derivação Gástrica/efeitos adversos , Humanos , Obesidade Mórbida/cirurgia , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/etiologia , Melhoria de Qualidade , Estudos Retrospectivos , Resultado do Tratamento
9.
Case Rep Transplant ; 2019: 9089317, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31428509

RESUMO

Chyle leaks may occur as a result of surgical intervention. Chyloperitoneum, or chylous ascites after liver transplantation, is rare and the development of chylothorax after abdominal surgery is even more rare. With increasingly aggressive surgical resections, particularly in the retroperitoneum, the incidence of chyle leaks is expected to increase in the future. Here we present a unique case of a combined chylothorax and chyloperitoneum following liver transplantation successfully managed conservatively. Risk factors for chylous ascites include para-aortic manipulation, extensive retroperitoneal dissection, use of a Ligasure device, and early enteral feeding as well as early enteral feeding. The clinical presentation is typically insidious and may include painless abdominal distension. Diagnosis can be made by noting characteristic milky white drainage which on laboratory examination has a total fluid triglyceride level >110 mg/dl, an ascites/serum triglyceride ratio of >1 and a leukocyte count in fluid >1000/uL with a lymphocyte predominance. Chyle leaks may lead to significant morbidity and mortality. Numerous management options exist, with conservative nonoperative measurements leading to the most consistent and successful outcomes. This includes a step-up approach beginning with dietary modifications to a low-fat or medium chain triglyceride diet followed by nil per os with addition of total parenteral nutrition and somatostatin analogues such as octreotide. Rarely do patients require more invasive treatment. Early recognition and appropriate management are imperative to mitigate this complication.

10.
Curr Gastroenterol Rep ; 21(9): 41, 2019 Jul 25.
Artigo em Inglês | MEDLINE | ID: mdl-31346780

RESUMO

PURPOSE OF REVIEW: Gastroesophageal reflux disease (GERD) affects millions of people worldwide. Many patients with medically refractory symptoms ultimately undergo antireflux surgery, most often with a laparoscopic fundoplication. Symptoms related to GERD may persist or recur. Revisional surgery is necessary in some patients. RECENT FINDINGS: A reoperative fundoplication is the most commonly performed salvage procedure for failed fundoplication. Although redo fundoplication has been reported to have increased risk of morbidity compared with primary cases, increasing experience with the minimally invasive approach to reoperative surgery has significantly improved patient outcome with acceptable resolution of reflux symptoms in the majority of patients. Recurrence of reflux symptoms after an initial fundoplication requires a thorough work-up and a thoughtful approach. While reoperative fundoplication is the most common procedure performed, there are other options and the treatment should be tailored to the patient, their history, and the mechanism of fundoplication failure.


Assuntos
Fundoplicatura/efeitos adversos , Refluxo Gastroesofágico/cirurgia , Hérnia Hiatal/cirurgia , Estômago/cirurgia , Esofagectomia , Derivação Gástrica , Hérnia Hiatal/diagnóstico , Humanos , Laparoscopia , Recidiva , Reoperação , Falha de Tratamento
11.
Case Rep Crit Care ; 2019: 2987682, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30863646

RESUMO

INTRODUCTION: Isolated Clostridium difficile small bowel enteritis is a rare condition with significant morbidity and mortality. PRESENTATION OF CASE: An 83-year-old female with refractory ulcerative colitis underwent a total proctocolectomy and end ileostomy. Her postoperative course was complicated with return to the operating room for repair of an incarcerated port site hernia. Subsequently, she developed septic shock and multiorgan failure requiring intubation and mechanical ventilation, renal replacement therapy, and high dose vasopressors. Diagnostic workup revealed diffuse small bowel wall thickening on computed tomography scan as well as positive nucleic acid amplification test for C. difficile toxin B gene. Despite treatment with antibiotics and maximum attempts at resuscitation, the patient expired. Discussion. C. difficile infection most commonly affects the colon but rarely can involve the small bowel. The pathogenesis of C. difficile enteritis is unclear but is believed to mirror that of colitis. Surgical patients are susceptible for C. difficile infection, as they tend to be relatively immunosuppressed in the postoperative period. Radiologic findings of enteritis may mimic those of colitis and this includes small bowel dilation and thickening. Treatment for this condition has not been well established but it is approached similar to colitis. CONCLUSION: Despite an increase in the number of case reports of C. difficile enteritis, it continues to be a rare but potentially fatal infection. Clinicians should maintain a high index of suspicion especially in patients with inflammatory bowel disease who undergo colon resections.

12.
Int J Surg Case Rep ; 56: 78-81, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30851627

RESUMO

INTRODUCTION: Anatomical variants of the extrahepatic biliary tree are numerous, adding significantly to the risk of bile duct injury during cholecystectomy, especially when laparoscopic approach is employed. Duplicated cystic ducts draining a single gallbladder are extremely rare. PRESENTATION OF CASE: A 34-year-old female presented with signs and symptoms of acute cholecystitis which was confirmed on imaging. She was found to have an accessory cystic duct on laparoscopic cholecystectomy requiring conversion to open laparotomy with intraoperative cholangiogram to delineate the anatomy. DISCUSSION: In the English literature, there has been 20 reported cases of double cystic duct with a single gallbladder. Most of these cases were diagnosed intraoperatively despite the completion of a preoperative endoscopic retrograde cholangiopancreatography in a few of these patients. CONCLUSION: The limited success of preoperative biliary tract imaging in demonstrating anatomic aberrancies prior to cholecystectomy clearly highlights the importance of maintaining constant vigilance for even the slightest anatomic abnormality at operation. Any uncertainty or concern for ductal injury mandates immediate operative cholangiogram with cannulation of all structures in question.

13.
Int J Surg Case Rep ; 57: 71-73, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30921589

RESUMO

INTRODUCTION: Nephrogenic diabetes insipidus occurs in patients on chronic lithium treatment even after lithium discontinuation. Patients affected by this disorder are highly vulnerable to hypernatremia when they cannot respond to their thirst mechanism. We report a rare case of hypernatremia due to undiagnosed nephrogenic diabetes insipidus post esophagectomy in a patient with remote history of lithium use. PRESENTATION OF CASE: A 70-year-old female with past medical history of bipolar disorder, chronic kidney disease and pheochromocytoma underwent an elective esophagectomy for esophageal adenocarcinoma. Lithium was discontinued 10 years prior to her presentation. She was kept nil per os post operatively and subsequently developed altered mental status necessitating intubation. Her sodium level was found to be 156 mmol/L. A water deprivation test and desmopressin trial confirmed nephrogenic diabetes insipidus. Days after dextrose 5% in water infusion, free water flushes through the jejunostomy tube and hydrochlorothiazide, her hypernatremia improved slowly with subsequent improvement in her mental status. DISCUSSION: Several mechanisms have been described in literature to explain the persistent damage caused by lithium on the kidneys. When patients lose access to a source of free water and are resuscitated with normal saline post operatively, they are at risk of developing life-threatening hypernatremia. This can be avoided by aggressive hydration with appropriate fluid replacement. CONCLUSION: Surgeons should be aware of the persistent renal defects caused by long term lithium use and development of nephrogenic diabetes insipidus even years after medication cessation.

14.
Obes Surg ; 28(12): 3923-3928, 2018 12.
Artigo em Inglês | MEDLINE | ID: mdl-30069860

RESUMO

BACKGROUND: Exercise is a strong determinant of prolonged weight loss in non-surgical patients. Studies evaluating the impact of exercise beyond the first year after bariatric surgery are lacking. We analyzed the relationship between reported intentional exercise and medium-term weight loss following bariatric surgery. METHODS: Patients who underwent bariatric surgery from 2007 thru 2013 completed a follow-up telephone survey and were separated into groups based on reported weekly exercise, i.e., < 90 min week-1, 90-200 min week-1, and > 200 min week-1. Standardized weight loss measures including percent of total weight loss, percent of excess body mass index (BMI) loss, percent of excess weight loss, and change in BMI were compared using analysis of covariance, with years from surgery as the covariant. RESULTS: A total of 872 patients were included in this study (age = 48 ± 10 years; BMI = 48 ± 7 kg/m2), with a mean post-surgery follow-up of 39 ± 14 months. Patients reporting > 200 min week-1 of planned exercise had greater weight loss than those who did less than 90 min week-1 (p < 0.05). No significant difference was found between those who reported less than 90 min week-1and those reporting between 91 and 200 min week-1. CONCLUSIONS: This study suggests that regular exercise in excess of 200 min week-1 is associated with greater medium-term weight loss following laparoscopic bariatric surgery. Multidisciplinary bariatric surgery teams should consider emphasizing exercise at this level to help patients achieve optimal weight loss.


Assuntos
Cirurgia Bariátrica , Exercício Físico , Laparoscopia , Obesidade Mórbida/cirurgia , Redução de Peso , Adulto , Índice de Massa Corporal , Estudos Transversais , Feminino , Comportamentos Relacionados com a Saúde , Humanos , Masculino , Pessoa de Meia-Idade , Resultado do Tratamento
15.
Clin Colon Rectal Surg ; 31(4): 209-213, 2018 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-29942208

RESUMO

Colonic diverticular disease is a common health care issue which has historically been attributed to western countries and older age population. Recent studies have shown a rise in incidence among developing countries that have adopted western diets as well as rise in prevalence among younger patients. In this article, the authors discuss the incidence, epidemiology, and pathophysiology of colonic diverticular disease.

16.
Ann Vasc Surg ; 39: 182-188, 2017 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-27531092

RESUMO

BACKGROUND: The aim of this study is to evaluate and define the expected flow pattern changes of carotid artery duplex ultrasound after left ventricular assist device (LVAD) placement. METHODS: Retrospective review of Henry Ford Hospital database of patients who had undergone LVAD placement between March 2008 and July 2012 was performed. All patients who had carotid artery duplex scanning before and after LVAD placement within 2 years of each other and showed <50% stenosis were included in this study. Type of waveform, carotid peak systolic velocity, and end-diastolic velocities were analyzed, and the values were compared before and after LVAD placement. RESULTS: A total of 13 patients with LVAD had at least 2 carotid duplex studies before and after LVAD placement within 2 years of each other. Of those, 92% (n = 12) were men, and 61% (n = 8) were Caucasian. Mean age was 61 years old. The HeartWare ventricular assist device was implanted in 4 patients and the HeartMate II left ventricular assist device was implanted in 9 patients. Post-LVAD Doppler imaging demonstrated parvus tardus waveform. Analysis of flow velocities revealed that peak systolic velocity was diminished after LVAD placement in both the internal and common carotid arteries (P = 0.006 and P < 0.0001, respectively). End-diastolic velocity, however, increased post-LVAD (P < 0.0001). Interestingly, mean flow velocities in both the common and internal carotid arteries remained stable after LVAD placement. CONCLUSIONS: This study reveals changes in waveform morphology and peak systolic and diastolic velocities in the common and internal carotid arteries on carotid duplex after LVAD placement. Additionally, it shows that despite changes in post-LVAD pulse pressure in the carotid arteries, the mean flow velocity remained unchanged.


Assuntos
Artéria Carótida Primitiva/fisiopatologia , Estenose das Carótidas/fisiopatologia , Insuficiência Cardíaca/terapia , Coração Auxiliar , Função Ventricular Esquerda , Idoso , Velocidade do Fluxo Sanguíneo , Pressão Sanguínea , Artéria Carótida Primitiva/diagnóstico por imagem , Artéria Carótida Interna/diagnóstico por imagem , Artéria Carótida Interna/fisiopatologia , Estenose das Carótidas/complicações , Estenose das Carótidas/diagnóstico por imagem , Bases de Dados Factuais , Progressão da Doença , Feminino , Insuficiência Cardíaca/complicações , Insuficiência Cardíaca/diagnóstico por imagem , Insuficiência Cardíaca/fisiopatologia , Humanos , Masculino , Michigan , Pessoa de Meia-Idade , Desenho de Prótese , Fluxo Sanguíneo Regional , Estudos Retrospectivos , Índice de Gravidade de Doença , Fatores de Tempo , Resultado do Tratamento , Ultrassonografia Doppler em Cores
17.
JAMA Surg ; 148(5): 408-11, 2013 May.
Artigo em Inglês | MEDLINE | ID: mdl-23677401

RESUMO

IMPORTANCE: Total proctocolectomy with ileal pouch-anal anastomosis is considered the procedure of choice for patients requiring elective surgery for ulcerative colitis, but some patients undergoing subtotal colectomy with end ileostomy are satisfied with an ileostomy and do not choose to undergo later pelvic pouch surgery. The need and timing for completion proctectomy in this setting are uncertain. OBJECTIVE: To assess the long-term fate of the retained rectum compared with the morbidity associated with completion proctectomy in patients who underwent subtotal colectomy for ulcerative colitis. DESIGN AND SETTING: Retrospective review of a prospective database in an academic medical center. PARTICIPANTS: Patients who underwent subtotal colectomy with ileostomy for ulcerative colitis from July 1, 1990, to December 31, 2010. MAIN OUTCOMES AND MEASURES: Proctectomy, surgical complications, and symptoms from the retained rectum. RESULTS: One hundred eight patients underwent subtotal colectomy for ulcerative colitis during the study period: 73 for acute disease, 18 for advanced age and/or comorbidities, and 17 to avoid the risk of sexual dysfunction or infertility. Of these patients, 71 (65.7%) underwent subsequent ileal pouch-anal anastomosis, 2 died of other causes, and 3 were lost to follow-up. Of the remaining 32 patients, 20 chose rectal stump surveillance and 12 underwent elective proctectomy. Median follow-up was 13.8 years. No difference was noted in age, sex, surgical complications, pad use, or urinary dysfunction between the 2 groups. Only 8 of 20 patients in the surveillance group were compliant with follow-up endoscopy, and 13 were able to maintain their rectum; 2 required proctectomy at 11 and 16 years, respectively, for rectal cancer; neither has developed recurrent disease. One patient in each group reported erectile dysfunction. CONCLUSIONS AND RELEVANCE: Management of the retained rectum after subtotal colectomy remains an important issue even in the era of ileal pouch-anal anastomosis. Considering the risk of rectal cancer, the low success rate of long-term rectal preservation, and the safety of surgery, a more aggressive approach to early completion proctectomy seems justified in this situation.


Assuntos
Colectomia , Colite Ulcerativa/cirurgia , Bolsas Cólicas , Ileostomia , Adulto , Idoso , Colite Ulcerativa/complicações , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Satisfação do Paciente , Reto , Estudos Retrospectivos , Resultado do Tratamento , Adulto Jovem
18.
Philos Trans A Math Phys Eng Sci ; 368(1923): 3243-53, 2010 Jul 28.
Artigo em Inglês | MEDLINE | ID: mdl-20566509

RESUMO

A major challenge in obtaining long-term durability in fuel cells is to discover catalyst supports that do not corrode, or corrode much more slowly than the current carbon blacks used in today's polymer electrolyte membrane fuel cells. Such materials must be sufficiently stable at low pH (acidic conditions) and high potential, in contact with the polymer membrane and under exposure to hydrogen gas and oxygen at temperatures up to perhaps 120 degrees C. Here, we report the initial discovery of a promising class of doped oxide materials for this purpose: Ti(1-x)M(x)O(2), where M=a variety of transition metals. Specifically, we show that Ti(0.7)W(0.3)O(2) is electrochemically inert over the appropriate potential range. Although the process is not yet optimized, when Pt nanoparticles are deposited on this oxide, electrochemical experiments show that hydrogen is oxidized and oxygen reduced at rates comparable to those seen using a commercial Pt on carbon black support.


Assuntos
Biocombustíveis , Fontes de Energia Elétrica , Polímeros/química , Conservação dos Recursos Naturais , Eletricidade , Eletroquímica/métodos , Eletrodos , Fontes Geradoras de Energia , Concentração de Íons de Hidrogênio , Teste de Materiais , Nanopartículas/química , Nanotecnologia/métodos , Platina/química , Titânio/química , Difração de Raios X
19.
Acta Crystallogr Sect E Struct Rep Online ; 66(Pt 5): e26, 2010 Apr 14.
Artigo em Inglês | MEDLINE | ID: mdl-21578981

RESUMO

The acknowledgement in the paper by Munie, Larsen & Gembicky [Acta Cryst. (2008), E64, m293] is extended and an omitted reference is added.[This corrects the article DOI: 10.1107/S1600536807067426.].

20.
Acta Crystallogr Sect E Struct Rep Online ; 64(Pt 2): m293, 2008 01 04.
Artigo em Inglês | MEDLINE | ID: mdl-21201270

RESUMO

The title compound, [Ru(C(10)H(15))(NO)(HOCH(2)CH(2)OH)](CF(3)SO(3))(2), possesses a three-legged piano-stool geometry around the Ru atom, with an average Ru-O distance of 2.120 (6) Šand an Ru-N-O angle of 159.45 (14)°. The ethyl-eneglycol ligand forms a non-planar metallacyclic ring by chelating the Ru atom via the O atoms. The O⋯O distances of 2.554 (2) and 2.568 (2) Šare indicative of hydrogen bonding between coordinated ethyl-eneglycol and outer-sphere trifluoro-methane-sulfonate fragments. The crystal packing is stabilized by ionic forces and several CH(3)⋯·F (2.585 and 2.640 Å) and CH(3)⋯O inter-actions (2.391, 2.678, 2.694 and 2.699 Å) between the penta-methyl-cyclo-penta-dienyl ligand and trifluoro-methane-sulfonate anion. There is noticeable short inter-molecular contact [2.9039 (16) Å], between an O atom of the SO(3) group and a C atom of the penta-methyl-cyclo-penta-dienyl ligand.

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