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1.
Skeletal Radiol ; 52(10): 1803-1814, 2023 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-35840815

RESUMO

Cancer is a leading cause of death, with the spine being the most common site for skeletal metastasis. The spine is also a site for primary malignancy, such as sarcoma and chordoma, as well as non-neoplastic pathologies. An accurate diagnosis of spinal neoplastic diseases is crucial in determining appropriate management. With the advent of personalised oncology, the need to establish a definitive histopathologic diagnosis to guide management is more important than ever. Percutaneous biopsy has proven to be safe and efficient in establishing a reliable histopathologic diagnosis. The spine, however, can be a challenging site to biopsy, due to the proximity of critical neurovascular, respiratory, and gastrointestinal structures. Successful spine biopsy depends on several factors: suspected diagnosis, size of the lesion, location within the spine, modality for best imaging guidance, operator experience, technical equipment considerations, and desired approach and associated limitations. The specimen must also be obtained with a biopsy route amenable to any future surgical intervention, with surgical input often sought, frequently in a multidisciplinary setting, to confirm procedure-specific goals and expectations. Knowledge of the requisite local anatomy, procedural and patient-specific indications, and contraindications and various approaches that may be used to access different segments of the spine, potential complications, and how to address these are keys to a successful percutaneous spinal biopsy, even in the most challenging of circumstances.


Assuntos
Doenças da Coluna Vertebral , Coluna Vertebral , Humanos , Estudos Retrospectivos , Coluna Vertebral/diagnóstico por imagem , Coluna Vertebral/cirurgia , Coluna Vertebral/patologia , Biópsia/métodos , Doenças da Coluna Vertebral/diagnóstico por imagem , Doenças da Coluna Vertebral/patologia
2.
J Radiol Case Rep ; 11(4): 30-37, 2017 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-28567183

RESUMO

Throughout recent years, Gabapentin has become increasingly used for the treatment of neuropathic pain. We report on a case of a 31 year old female who presented to the emergency department with unilateral leg pain, weakness, and swelling after increasingly titrating her Gabapentin dosage over three weeks. Magnetic resonance imaging confirmed the presence of myositis confined to the left thigh and the patient's symptoms and laboratory abnormalities resolved following Gabapentin cessation. While Gabapentin-induced myositis and rhabdomyolysis is a rare entity, it should be a diagnostic consideration for radiologists, particularly in the absence of infection or trauma.


Assuntos
Aminas/efeitos adversos , Analgésicos/efeitos adversos , Ácidos Cicloexanocarboxílicos/efeitos adversos , Miosite/induzido quimicamente , Miosite/diagnóstico por imagem , Neuralgia/tratamento farmacológico , Ácido gama-Aminobutírico/efeitos adversos , Adulto , Biomarcadores/sangue , Angiografia por Tomografia Computadorizada , Meios de Contraste , Diagnóstico Diferencial , Feminino , Gabapentina , Humanos , Perna (Membro) , Imageamento por Ressonância Magnética , Ultrassonografia Doppler
4.
AJR Am J Roentgenol ; 203(1): W103-9, 2014 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-24951221

RESUMO

OBJECTIVE: The objective of our study was to discover the types and incidence of artifacts in dual-energy CT (DECT) using datasets of 50 consecutive patients who underwent a four-limb DECT protocol for the evaluation of suspected gout. Identification of artifacts and techniques for artifact reduction are discussed. CONCLUSION: Artifacts commonly occur in DECT performed for gout assessment but are usually readily recognizable. For 90% of the patients in our study who underwent imaging for suspected gout, DECT showed some type of artifact, with nail bed and skin artifacts being the most common.


Assuntos
Artefatos , Gota/diagnóstico por imagem , Tomografia Computadorizada por Raios X/métodos , Adulto , Idoso , Algoritmos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Interpretação de Imagem Radiográfica Assistida por Computador
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