RESUMO
IMPORTANCE: Patients with neuromyelitis optica who have aquaporin-4 antibodies are being identified and receiving immunosuppressant treatment earlier and more aggressively as a result of increasing awareness of the importance of preventing relapses responsible for the high morbidity and mortality associated with the disease. To our knowledge, opportunistic retinal infection in patients with aquaporin-4 antibodies who are receiving immunosuppressants has not been reported to date. OBSERVATIONS: We describe 2 patients with aquaporin-4 antibodies who were receiving conventional doses of first-line immunosuppressive therapy. Both patients presented with vision loss that was initially thought to be optic neuritis attacks. The subsequent diagnoses were ocular toxoplasmosis and cytomegalovirus retinitis. CONCLUSIONS AND RELEVANCE: Retinal opportunistic infections can occur in patients with aquaporin-4 antibodies who are receiving relatively low levels of immunosuppression, may mimic optic neuritis, and are a potentially reversible cause of vision loss when treated promptly.
Assuntos
Aquaporina 4/metabolismo , Neuromielite Óptica/imunologia , Infecções Oportunistas/etiologia , Neurite Óptica/imunologia , Retina/imunologia , Idoso , Anticorpos/efeitos adversos , Anticorpos/uso terapêutico , Aquaporina 4/imunologia , Feminino , Humanos , Imunossupressores/uso terapêutico , Pessoa de Meia-Idade , Neuromielite Óptica/diagnóstico , Neuromielite Óptica/tratamento farmacológico , Infecções Oportunistas/imunologia , Neurite Óptica/complicaçõesRESUMO
Capsules containing liquid laundry detergent have recently become popular. We describe six children who presented with ocular surface injuries due to the bursting of such capsules.
Assuntos
Queimaduras Químicas/etiologia , Cápsulas/efeitos adversos , Córnea/efeitos dos fármacos , Detergentes/efeitos adversos , Queimaduras Oculares/induzido quimicamente , Queimaduras Químicas/terapia , Pré-Escolar , Cloranfenicol/uso terapêutico , Quimioterapia Combinada , Queimaduras Oculares/terapia , Ácido Fusídico/uso terapêutico , Humanos , Lactente , Soluções Oftálmicas , Irrigação TerapêuticaRESUMO
PURPOSE: To report a case that suggests that factors associated with daily disposable contact lenses contribute to the risk of developing infectious keratitis. METHODS: A case of a culture-positive Pseudomonas corneal ulcer in a compliant daily disposable contact lens wearer is presented. RESULTS: The case involves a 35-year-old woman with a culture-positive Pseudomonas corneal ulcer that was treated successfully with topical antibiotics. The patient wore daily disposable contact lenses on a part-time basis and was fully compliant with the instructions for use. CONCLUSIONS: Compliance and wearing time were not causal in this episode of infectious keratitis, but factors related to the lens might have been.
