[Reamberin application in the treatment of obturational jaundice of nontumoral etiology].

The influence of the preparation reamberin on endogenic intoxication severity in the patients, operated on for obturational jaundice of nontumoral etiology, was studied up. In 10 patients 1.5% solution of reamberin, infused continuously intravenously in 400 ml/day dosage during 3-10 days, was applied in complex postoperative therapy. It was established, that obturational jaundice of nontumoral etiology goes together with endogenic intoxication and the antioxidant defence system (ADS) inhibition. The preparation reamberin application had promoted more rapid normalization of the endotoxicosis and ADS indexes, comparing with such in controls.

[Efficacy of antibiotic prophylaxis using zinacef in postoperative period].

The results of intravenous injection of Zinacef for purulent--septic complications in patients with various acute surgical diseases of the abdominal cavity organs were presented. Main principles and rules of antibioticoprophylaxis and antibioticotherapy conduction in surgery were substantiated.

[A new theoretical and experimental validation of the treatment and prevention of cholelithiasis]. / Novoe teoreticheskoe i éksperimental'noe obosnovanie lecheniia i profilaktiki kholelitiaza.

Approaches are proposed, new in principle, toward breaking biliary calculi into pieces, as well as toward prophylaxis of cholelithiasis. Exposure of the concrements to ultrasound with varying resonance frequency in a contact medium containing litholytic substances permits bringing about their reduction to fragments being safe for their evacuation from the biliary system. Prevention of cholelithiasis involves identification of precalculous period and exposure of the gallbladder region to vibration along with adopting conventional therapy.

[Surgical treatment of open and closed injuries of the duodenum]. / Khirurgicheskoe lechenie otkrytykh i zakrytykh povrezhdenii dvenadtsatiperstnoi kishki.

The article discusses a complex of methods for the diagnosis of injuries to the duodenum in 18 patients. Laboratory and X-ray findings and laparocentesis with introduction of a "feeling" catheter into the abdominal cavity with lavage of the cavity facilitated the discovery of blood and intestinal contents and allowed the correct diagnosis to be established before the operation. In inspection of the duodenum mobilization after Kocher is insufficient, in rupture of the posterior wall in the region of the inferior horizontal part the duodenum must be mobilized for its whole length. It is advisable that the defect in the duodenum is closed with a double-row suture applied with an atraumatic needle (the first inner row of interrupted sutures). The methods for applying hemostatic sutures suggested by the authors by means of created devices provide reliable hemostasis in combined injuries to the parenchymatous organs. The operation was completed by leaving glove-tube drains. The postoperative mortality was 16.6%.

[Changes in immunologic reactivity in patients with gastrointestinal bleeding]. / Izmenenie immunologicheskoi reaktivnosti u bol'nykh s zheludochno- kishechnym krovotecheniem.

The disorders in immunologic reactivity in acute gastrointestinal bleeding were studied in dynamics in 160 patients. Pronouncement of disorders in the T-system of immunity, activation of the reactions of specific sensibilization and autoallergic phenomena depend on severity of the blood loss. In ulcer location in the duodenum, the performance of an organ-preserving operation with vagotomy and elimination of the ulcer which is a source of antigen stimulation is preferable.