1.
Bioorg Med Chem Lett
; 12(3): 383-6, 2002 Feb 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-11814802
RESUMO
The synthesis, antibacterial activity and DHP-susceptibility of a series of novel carbapenems, directly linked with heterocyclic moiety are described. Especially, the compounds linked pyrrolidine-carbapenem exhibited to have a good antibacterial activity against Staphylococcus aureus (MRSA) as well as Pseudomonas aeruginosa to maintain a good stability towards DHP-I.