Collagen type III in rotator cuff tears: An immunohistochemical study.

The presence and distribution of collagen type III, which represents newly formed fibers of early repair, were investigated in four surgically removed en bloc specimens of complete rotator cuff tears. The patients were two men and two women who ranged in age from 63 to 71 years. They had received preoperative, conservative treatment for a period varying from 3 months to 3 years. For the identification of the collagen immunohistochemical staining was performed by the peroxidase-antiperoxidase method with the use of monoclonal antibody against human collagen type III. Collagen type III was discernible throughout the tendon proper in all specimens. It often occurred in association with proliferating fibroblastic cells. Collagen type III was abundant only in the perivascular spaces of the much thickened bursal wall that extended over the margins of the tear. We concluded that the presence of collagen type III indicates the need for a continued attempt for repair at the site of the tear, including both bursal and tendinous tissues.

Adhesive capsulitis of the shoulder: current concepts and treatment.

Primary adhesive capsulitis of the shoulder is a common cause of a painful shoulder in clinical practice. The pathogenesis remains unclear. Many patients continue to have significant long-term restrictions in their range of motion although few are functionally restricted. Prevention is the ideal treatment. Patients respond to treatment plans directed at pain relief and improving the range of motion, however, ongoing controlled therapeutic trials are necessary to better refine the selection of treatment for individual patients.

The holding power of orthopedic screws in vivo.

Great difficulty is encountered in choosing screws for internal fixation, for screws differ in material, geometry, dimension, and in insertion technique. Recently claims have been made that self-tapping screws cause necrosis of bone and result in fibrous tissue formation, with loss of holding power. This investigation was undertaken to study the healing of bone about screws inserted for a period of 3 months. Self tapping and non-self tapping screws were employed. The Vitallium screws not only differed in dimension, but also in configuration of the thread, with the smaller of the self-tapping screws exhibiting a "V" thread in distinction to the buttress thread of the larger screw. The histologic data were correlated with the holding power of the screws as obtained by means of a push out test, performed with the aid of an Instrom testing machine. The largest screw tested, the 4.5 mm non-self tapping stainless steel AO screw (Type 1), provided the greatest safety factor to push out loading over the period tested in the unloaded system. The self tapping and non-self tapping screws of similar material and size were found to maintain comparable holding power at all intervals tested in vivo in the unloaded system. No histological differentiation could be made with regard to both death or tissue reaction around the implant, between the stainless steel or cobalt chromium alloy materials, nor between the self tapping and non-self tapping insertion methods.

Methymethacrylate cement: its curing temperature and effect on articular cartilage.

The increasing use of methylmethacrylate in orthopedic surgery makes it desirable to determine whether the curing temperature of methylmethacrylate is high enough to cause bone necrosis and whether methylmethacrylate damages articular cartilage. Studies in dogs showed that methylmethacrylate plut temperatures ranged from 95 to 107degrees C and that temperatures at the cement-bone interface ranged from 50 to 95degrees. Curing temperatures therefore are high enough to cause necrosis of bone. Other studies revealed no harmful action of methylmethacrylate on articular cartilage. Fractures stabilized with methylmethacrylate can therefore be expected to heal provided the normal criteria of fracture management are fulfilled.