Genetic diversity and seroprevalence of Toxoplasma gondii in COVID­19 patients; a first case-control study in Iran.

BACKGROUND: Toxoplasmosis is a serious or life-threatening disease in immunosuppressed patients and pregnant women. This study examined the likely association between Toxoplasma gondii infection and COVID-19 patients with moderate illness. METHODS: Seventy blood samples were collected from patients at the Health Reference Laboratory of Tabriz, Northwest Iran from April 2021 to September 2021. In addition, 70 healthy subjects of the same age (37 ± 15 years) and sex distribution were ethnically matched. Sera samples were examined for the detection of anti-Toxoplasma antibodies using ELISA. Nested-PCR targets were amplified based on the B1 and GRA6 genes. GRA6 amplicons were subjected to sequencing and phylogenetic analysis. RESULTS: The seroprevalence of toxoplasmosis based on IgG titer was 35.7% in the COVID­19 patients and 27.1% in the control group, representing not to be associated with the Toxoplasma seropositivity in COVID­19 patients (P = 0.18) compared to healthy subjects. Anti-T. gondii IgM was not found in any of the patients and healthy individuals. According to PCR amplification of the B1 and GRA6 genes, the frequency of T. gondii in COVID-19 patients was 14.2% (10/70). However, no T. gondii infection was detected in the healthy group. The CD4+T cell count was relatively lower in toxoplasmosis-infected patients (430-450 cells/mm3) than in control group (500-1500 cells/mm3). High genetic diversity (Hd: 0.710) of the type I strain of T. gondii was characterized in the patients. Present results showed that consumption of raw vegetables and close contact with stray cats can increase the transmission of T. gondii to COVID-19 patients (P < 0.01). CONCLUSIONS: The current study revealed that T. gondii type I infection is unequivocally circulating among the COVID-19 patients in Tabriz; However, no significant association was observed between the occurrence of Toxoplasma and the severity of COVID-19. To make more accurate health decisions, multicenter investigations with a larger sample size of different ethnic groups of the Iranian population are needed.

Psychometric properties of the Last-7-Day Sedentary Time Questionnaire (SIT-Q-7d): Testing the validity and reliability among general population.

BACKGROUNDS: Sedentary behavior (SB) is an independent risk factor causing chronic diseases. Previous studies compared sitting time mostly with physical activity. The present study aimed to evaluate the validity and reliability of the Last-7-Day Sedentary Time Questionnaire (SIT-Q-7d) in Iran. Moreover, SB was assessed among the study participants. METHODS: The current validity study was conducted among 290 subjects (51.7% males vs. 48.3% females) with a mean age of 34.81 ± 9.63 years in Poldasht, Iran. Sampling was done using simple random sampling and the data were collected using the SIT-Q-7d. To confirm the validity of the questionnaire, forward-backward translation method, content validity, and construct validity were used. Furthermore, temporal stability was calculated by the test-retest method and internal consistency coefficient (ICC). RESULTS: Our results confirmed the content validity of the questionnaire (content validity score: 0.90 and content validity index: 0.80). Using exploratory factor analysis (EFA), seven factors of SB were identified as follows: eating while sitting down, doing domestic affairs, screen time, leisure time, studying books, watching TV, and attending family gatherings. The reliability of the questionnaire was confirmed using Cronbach's alpha (α = 0.7). In addition, temporal stability was confirmed by test-retest method and ICC was 0.9 (95% CI: 83-97). CONCLUSION: Our results confirmed that the Persian version of SIT-Q-7d is a reliable and valid tool for assessing SB.

Gaming disorder among students of Tabriz University of Medical Sciences: The frequency and related factors.

Background: Gaming disorder has been identified as a health problem. Disorders in emerging adulthood might negatively affect individuals' attitude toward the world, their communication with others, and formation of their personal identity. Thus, the present study was performed to identify the frequency of gaming disorder and its related factors among students of Tabriz University of Medical Sciences. Methods: A total of 813 undergraduate students of Tabriz University of Medical Sciences participated in this descriptive correlational study in 2018. All students filled the personal-social information form and Social Readjustment Rating Scale, and gamers filled gaming behaviors form and Internet gaming disorder-20 test (IGD). Data were analyzed using descriptive statistics and Pearson correlation coefficient, t- test, ANOVA, chi-square, and multiple linear regression. Results: A total of 394 (48.5%) students were currently playing games. The mean of IGD scores among the gamers was 45.47 ±13.93, and 17 (4.3%) of them were recognized as having gaming disorder. The frequency of the disorder among all students was 17 (2.1%). Being male, playing online games, and having access to all 3 gaming devices (computer, smart phone, and tablet) were recognized as determining factors of gaming disorder. Conclusion: This study revealed that almost half of the university students were playing video and or on line games; however, a low percentage of the gamers had addictive gaming behaviors. The results indicated the necessity of applying modifications to individuals' gaming methods as well as implementing the individual and family-centered interventions to prevent and manage gaming disorder.

Relationship between Extraversion and Tobacco Smoking Among High School Students.

BACKGROUND: There is limited information about the relationship between extraversion, as a personality trait, and the modes of tobacco smoking. The aim of this study was to investigate the relationships between extraversion and cigarette and water-pipe smoking among a representative sample of Iranian high school students. METHODS: A sample of 2,312 tenth-grade students in Tabriz (Northwest of Iran) was selected through multistage proportional cluster sampling. Participants completed a self-administered questionnaire including information on cigarette smoking, water-pipe smoking, extraversion, socioeconomical information, as well as demographic characteristics. An ordinal logistic regression model was used for data analysis. RESULTS: In total, 4.2% and 3.5% of the students were regular cigarette and water-pipe smokers, respectively. The adjusted odds ratios were 1.10 (95% CI: 1.04-1.15, P < 0.001) and 1.10 (95% CI: 1.06-1.15, P < 0.001) for the relationships between extraversion and the stages of cigarette smoking and water-pipe smoking status, respectively. CONCLUSIONS: It seems that extraversion is in a positive relationship with a cigarette and water-pipe smoking among adolescents. Longitudinal studies are needed to examine the effect of this personality trait on the modes of tobacco smoking and the transition in the stages of cigarette and water-pipe smoking in adolescents.

Adolescent cancer survivors' experiences of supportive care needs: A qualitative content analysis.

Supportive care is an important strategy that can help cancer survivors manage changes and problems during their follow-up care. Identifying patients' care needs is one of the primary steps of the nursing process to plan effective nursing interventions. The aim of this study was to explore adolescent cancer survivors' supportive care needs. Purposeful sampling was adopted to select 49 participants from hospitals to participate in face-to-face, semistructured interviews. The qualitative content analysis method was conducted for data analysis. Ten subcategories and four main categories - empathetic care, information about survival period, instrumental support, and cooperation in care - were extracted from the data. These four categories formed a major theme, "supportive care", as the primary healthcare need. This study highlights that supportive care should be developed collaboratively by family and healthcare providers to meet the needs of adolescent cancer survivors. Survivors' strengths and limitations should be identified, and then supportive care can be provided, such as giving appropriate information, enabling survivors to access supportive networks, and improving survivors' confidence and autonomy with their self-management.

Experience of Adolescent Survivors of Childhood Cancer about Self-Care Needs: A Content Analysis.

OBJECTIVE: In cancer care management, patients or their family are usually responsible for continuing health care. Achieving this goal requires identification of their self-care needs. The purpose of this study is to explore the perception of self-care needs of adolescent cancer survivors. METHODS: This study was conducted by the qualitative content analysis method. Participants were 19 adolescent childhood cancer survivors and six parents, nurses, physicians, and charity institution staff from children teaching hospitals in Iran. Participants were selected through purposeful sampling, and individual semistructured interviews were used for data collection. Graneheim and Lundman stages of content analysis were employed for data analysis. Data were managed with the MAXQDA10 software. RESULTS: Content analysis revealed nine subcategories as follows: (1) nutritional protection, (2) prevention from infection, (3) prevention from physical damage, (4) control over cancer recurrence, (5) informational needs, (6) pain management, (7) releasing positive thoughts, (8) continuing routine life, and (9) family protection. The first six subthemes were related to protection against physical distress, and the final three ones were related to protection against psychological distress. These two categories form one theme: "protective self-care need" as an essential self-care need in adolescent cancer survivors. CONCLUSIONS: Pediatric and school health nurses can prepare strategies to meet these needs by providing effective informational and psychosocial supports, and healthcare providers are able to check periodically the status of survivors care to provide second or third level of care to prevent escalation and incidence of the adverse outcomes of the disease.

Why People Choose to Volunteer? Women Health Volunteers' Activities, Reasons for Joining and Leaving.

Introduction: Women health volunteers are the link between people and healthcare workers. They play an important role in health education activities, following up families under coverage, and updating the demographic data to health centers. This study was performed to uncover women health volunteers' activities, reasons for joining and leaving from the program. Methods: A qualitative study design was used to conduct the study. Through purposive sampling technique, twenty -four in-depth semi-structured individual interviews and two focused group discussions with women health volunteers and their supervisors were conducted in Tabriz, Iran. Data analysis implemented thematic analysis, using MAXQDA10. Results: The findings were generally categorized into three major themes, participation in promoting health, perceived benefit, and perceptual- environmental inhibitors. Participation in promoting health consisted of the sub-themes participation in educational programs, participation in health care. The sub-themes of perceived benefit included benefits from health care services and interest in having an active role in the community. The theme perceptual- environmental inhibitors involved the subthemes participation barriers and lack of innovation and inconsistency with social changes. Conclusion: Culture-building about the role of health volunteers, the valuing on their activities in the community, and informing program supervisors about the health volunteer's duties would help to retain health volunteers and also sustain their activities at the community level.

Effect of TiO2/GAC and water vapor on chloroform decomposition in a hybrid plasma-catalytic system.

This paper presents the combination of TiO2/GAC catalyst and NTP for the decomposition of chloroform using a DBD reactor. The experiments were performed using an AC transformer as the power supply system to determine the optimal conditions of the chloroform conversion in the presence of a hydrogen-rich substance, that is, water vapor. TiO2/GAC enhanced the removal efficiency and also CO2 selectivity significantly, leading to an acceptable conversion rate at SIEs higher than 400 J L-1. The adsorption property of GAC was noticed to be an effective factor for catalytic activity by increasing the residence time, although the higher retention time prevented the accurate determination of chlorine and carbon balance. Selectivity toward HCl was improved considerably from 24.3% to 64.3% over catalyst when water was fed as a hydrogen-rich compound. At the same time, the harmful chlorinated by-products such as TCBA and TCE declined significantly. A noticeable enhancement in the selectivity toward CO2 was observed when both catalyst and water were introduced, regardless of the inlet concentration. Our findings suggest that the hybrid of NTP with TiO2/GAC will highly be effective in the abatement of chloroform, and the addition of H2O will successfully decline harmful chlorinated by-products.

Manual material handling assessment among workers of Iranian casting workshops.

Manual material handling (MMH) tasks can be found in most workplaces and they may constitute a risk factor for work-related musculoskeletal disorders (WMSDs). This study was conducted to determine the prevalence of WMSDs and to compare MMH loads with the acceptable weight and force limits among Iranian casting workers. Data were collected from 50 workers of casting workshops who performed MMH tasks. The Nordic musculoskeletal disorders questionnaire and the Snook tables were used as tools for data collection. Hand/wrist symptoms were the most prevalent problems among the workers (84%). The results of the Snook tables showed that the loads in lifting (84%), lowering (86%), carrying (66%), pushing with initial (43%) and sustained force (59%), and pulling tasks with initial (48%) and sustained force (93%) exceeded recommended limits. WMSDs occurred in high rates among the workers and, thus, ergonomics interventions should focus on decreasing WMSDs and redesigning MMH tasks.

Ergonomics intervention in a tile industry- case of manual material handling.

BACKGROUND: Manual material handling is one of the major health and safety hazards in industry. This study aims to assess the lifting tasks, before and after intervention using NIOSH lifting equation and Manual Handling Assessment Charts (MAC). METHODS: This interventional study was performed in 2011 in a tile manufacturing industry in Hamadan, located in the West of Iran. The prevalence of musculoskeletal discomfort was determined using Nordic musculoskeletal questionnaire. In order to assess the risk factors related to lifting and identify the high-risk activities, MAC and NIOSH lifting equation were used. In intervention phase, we designed a load-carrying cart with shelves capable of moving vertically up and down, similar to scissor lifts. After intervention, the reassessment of risk factors was conducted to determine the success of the intervention and to compare risk levels before and after intervention using t-test. RESULTS: The outputs of MAC and NIOSH lifting equation assessments before intervention revealed that all activities were at high-risk level. After intervention, the risk level decreased to average level. CONCLUSION: In conclusion, the results of intervention revealed a considerable decrease in risk level. It may be concluded that the given intervention was acceptable and favorably effective in preventing musculoskeletal disorders especially low back pain.