RESUMO
The peculiar features of the clinical course and treatment of primary gastric MALT-lymphoma in 7 patients are discussed. Diagnosis was established by morphological examination of resected material. Six patients had low-grade tumor while one showed signs of blast-transformation. Stage IEB disease was identified in 4 cases, IIEB--3. Complete remission duration after combined surgical and chemoradiation treatment ranged 3.5-80 months (mean duration--35.1 months), survival--5-84 months (mean duration--43.1 months). Relapse was registered in one case 3.5 months after operation.
Assuntos
Linfoma de Zona Marginal Tipo Células B/patologia , Linfoma de Zona Marginal Tipo Células B/terapia , Neoplasias Gástricas/patologia , Neoplasias Gástricas/terapia , Adulto , Quimioterapia Adjuvante , Intervalo Livre de Doença , Feminino , Mucosa Gástrica/patologia , Humanos , Linfoma de Zona Marginal Tipo Células B/tratamento farmacológico , Linfoma de Zona Marginal Tipo Células B/radioterapia , Linfoma de Zona Marginal Tipo Células B/cirurgia , Masculino , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Radioterapia Adjuvante , Neoplasias Gástricas/tratamento farmacológico , Neoplasias Gástricas/radioterapia , Neoplasias Gástricas/cirurgia , Análise de Sobrevida , Resultado do TratamentoRESUMO
The authors present the results of the COP therapy of 85 patients with generalized lymphoblastic and immunoblastic lymphosarcomas. Antirelapse therapy with cyclophosphamide and reinduction courses according to the COP scheme and COP reinduction courses only increase the period of remission. A necessity of antirelapse therapy after achieving a complete remission is substantiated.
Assuntos
Linfoma não Hodgkin/tratamento farmacológico , Recidiva Local de Neoplasia/prevenção & controle , Adolescente , Adulto , Idoso , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Ciclofosfamida/administração & dosagem , Avaliação de Medicamentos , Feminino , Humanos , Linfoma não Hodgkin/patologia , Masculino , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Prednisolona/administração & dosagem , Fatores de Tempo , Vincristina/administração & dosagemRESUMO
Under study is the incidence of nonlymphogranulomatous lymphomas in the Moldavian SSR for a 10-year period depending on sex, age and nationality. Nonlymphogranulomatous lymphomas are more frequently observed among the urban population, and more often in males, the age peak among persons of both sex being over 60. There is a tendency to the increased incidence of this affection. It may be due to a longer patients' survival as a result of introducing some new more effective methods of treatment for the given lesion.
