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Public Health Nutr ; 16(9): 1605-13, 2013 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-23218415

RESUMO

OBJECTIVE: Simulating the probable impact of grain amaranth and highly absorbable, low-Fe micronutrient powder (MNP) on Fe status in a potential target population is an essential step in choosing and developing an appropriate actual intervention. DESIGN: We simulated the potential effect of fortifying maize porridge with grain amaranth or MNP on the prevalence of inadequate Fe intake and Fe deficiency using data from two cross-sectional surveys. In the first survey (2008), dietary intake data were collected by two 24 h recalls (n 197). Biochemical data (n 70) were collected in the second survey (2010). A simulation with daily consumption for 80 d of non-fortified maize porridge (60 g of maize flour), amaranth-enriched porridge (80 g of grain amaranth­maize flour, 70:30 ratio) or maize porridge fortified with MNP (2.5mg Fe as NaFeEDTA) was done. SETTING: Mwingi District, Kenya. SUBJECTS: Pre-school children aged 12­23 months. RESULTS: Prevalence of anaemia, Fe deficiency and Fe-deficiency anaemia was 49 %, 46% and 24 %, respectively. Consumption of non-fortified, amaranth-enriched and MNP-fortified maize porridge was estimated to provide a median daily Fe intake of 8.6 mg, 17.5mg and 11.1 mg, respectively. The prevalence of inadequate Fe intake was reduced to 35% in the amaranth-enriched porridge group and 45% in the MNP-fortified porridge group, while ferritin concentration was increased in both (by 1.82 (95% CI 1.42, 2.34) mg/l and 1.80 (95% CI 1.40, 2.31) µg/l, respectively; P,0.005) compared with the non-fortified maize porridge group, resulting in a decreased prevalence of Fe deficiency (27 %) in the two fortification groups. CONCLUSIONS: Addition of grain amaranth or low-Fe MNP to maize-based porridge has potential to improve Fe intake and status in pre-school children.


Assuntos
Amaranthus/química , Anemia Ferropriva/terapia , Compostos Férricos/uso terapêutico , Alimentos Fortificados , Ferro da Dieta/uso terapêutico , Ferro/uso terapêutico , Micronutrientes/uso terapêutico , Anemia/sangue , Anemia/epidemiologia , Anemia/terapia , Anemia Ferropriva/sangue , Anemia Ferropriva/epidemiologia , Estudos Transversais , Dieta , Ácido Edético/uso terapêutico , Ingestão de Energia , Feminino , Ferritinas/sangue , Humanos , Lactente , Ferro/administração & dosagem , Quelantes de Ferro/uso terapêutico , Deficiências de Ferro , Quênia/epidemiologia , Masculino , Rememoração Mental , Micronutrientes/administração & dosagem , Micronutrientes/deficiência , Modelos Biológicos , Estado Nutricional , Pós , Prevalência , Zea mays
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