RESUMO
We studied ultrastructural changes in cardiomyocytes and blood capillary endotheliocytes in the ventricular myocardium in response to mechanical injury of the heart of varying severity in Wistar rats. Acute alterative changes in cardiomyocyte and endotheliocyte ultrastructure indicate impairment of the energy-producing, contractile, and protein-synthesizing functions of the cells after mechanical injury. These disorders play the key role in the development of acute contractile insufficiency of the myocardium in mechanical injury to the heart.
Assuntos
Endotélio Vascular/patologia , Traumatismos Cardíacos/patologia , Miócitos Cardíacos/patologia , Animais , Células Endoteliais/patologia , Microscopia Eletrônica de Transmissão , Mitocôndrias Cardíacas/patologia , Miocárdio/patologia , Miofibrilas/patologia , Ratos WistarRESUMO
Changes in the placentas of pregnant C57Bl/6 mice infected with BCG vaccine were studied by light microscopy and morphometry. The decrease in the numbers of maternal and fetal vessels was paralleled by destructive changes and disorders in the compensatory reactions, which led to fetal hypotrophy after infection with BCG vaccine.
