1.
Angew Chem Int Ed Engl
; 53(41): 10997-1000, 2014 Oct 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25163804
RESUMO
A novel ring contraction/rearrangement sequence leading to functionalized 2,8-oxymethano-bridged di- and triquinane compounds is observed in the reaction of various substituted 1-methyl-4-isopropenyl-6-oxabicylo[3.2.1]octan-8-ones with Lewis acids. The reaction is novel and is unprecedented for the synthesis of di- and triquinane frameworks.
2.
Org Lett
; 15(11): 2778-81, 2013 Jun 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23701587
RESUMO
Synthesis of isochromanones and isoquinolones comprising a quaternary center with high diastereoselectivity was realized via a AuCl3 catalyzed tandem intramolecular exo-dig heterocyclization/enol isomerization/Claisen rearrangement sequence in excellent yields. The reaction is general and amenable for the synthesis of structurally diverse analogues.