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1.
Exp Parasitol ; 249: 108521, 2023 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-37011804

RESUMO

In the present study, the larvicidal efficacy of the juices of the weeds Lantana camara Linn (L. camara) and Ocimum gratissimum Linn (O. gratissimum) was evaluated against the larvae of the malaria vectors Aedes aegypti, Anopheles subpictus and Culex quinquefasciatus. The freshly prepared juices of leaves were prepared by grinding them and diluting them at concentrations of 25, 50, 75, and 100 ppm. Twenty larvae of each species were introduced in different sterile Petri dishes in aqueous media under a controlled environment for the assessment of biological activity. The larvicidal activity of both juices was evaluated at 6, 12 and 24 h post-exposure time points by observing the movement of each larva. The obtained data were subjected to probit analysis to determine the lethal concentrations that kill 50% and 90% (LC50 and LC90) of the treated larvae. The results revealed a noticeable larvicidal activity following 24 h of exposure. The juice of L. camara leaves exhibited an LC50 range of 47.47-52.06 ppm and an LC90 range of 104.33-106.70 ppm. Moreover, for the juice of O. gratissimum leaves, the LC50 range was 42.94-44.91 ppm and the LC90 range was 105.11-108.66 ppm. Taken together, the results indicate that the juices of L. camara and O. gratissimum leaves may be useful as effective, economical and eco-friendly larvicidal agents. However, additional studies are needed to explore the bioactive components of the weeds that exhibit larvicidal activity along with their mode of action.


Assuntos
Aedes , Culex , Inseticidas , Lantana , Ocimum , Animais , Mosquitos Vetores , Extratos Vegetais/farmacologia , Inseticidas/farmacologia , Larva , Folhas de Planta
2.
Comput Intell Neurosci ; 2022: 9737511, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35528349

RESUMO

The brain is the most complex organ in the human body, and it is also the most complex organ in the whole biological system, making it the most complex organ on the planet. According to the findings of current studies, modern study that properly characterises the EEG data signal provides a clear classification accuracy of human activities which is distinct from previous research. Various brain wave patterns related to common activities such as sleeping, reading, and watching a movie may be found in the Electroencephalography (EEG) data that has been collected. As a consequence of these activities, we accumulate numerous sorts of emotion signals in our brains, including the Delta, Theta, and Alpha bands. These bands will provide different types of emotion signals in our brain as a result of these activities. As a consequence of the nonstationary nature of EEG recordings, time-frequency-domain techniques, on the other hand, are more likely to provide good findings. The ability to identify different neural rhythm scales using time-frequency representation has also been shown to be a legitimate EEG marker; this ability has also been demonstrated to be a powerful tool for investigating small-scale neural brain oscillations. This paper presents the first time that a frequency analysis of EEG dynamics has been undertaken. An augmenting decomposition consisting of the "Versatile Inspiring Wavelet Transform" and the "Adaptive Wavelet Transform" is used in conjunction with the EEG rhythms that were gathered to provide adequate temporal and spectral resolutions. Children's wearable sensors are being used to collect data from a number of sources, including the Internet. The signal is conveyed over the Internet of Things (IoT). Specifically, the suggested approach is assessed on two EEG datasets, one of which was obtained in a noisy (i.e., nonshielded) environment and the other was recorded in a shielded environment. The results illustrate the resilience of the proposed training strategy. Therefore, our method contributes to the identification of specific brain activity in children who are taking part in the research as a result of their participation. On the basis of several parameters such as filtering response, accuracy, precision, recall, and F-measure, the MATLAB simulation software was used to evaluate the performance of the proposed system.


Assuntos
Internet das Coisas , Dispositivos Eletrônicos Vestíveis , Acústica , Algoritmos , Criança , Saúde da Criança , Eletroencefalografia/métodos , Humanos , Vocabulário
3.
Comput Intell Neurosci ; 2022: 1797471, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35419047

RESUMO

The lack of annotated datasets makes the automatic detection of skin problems very difficult, which is also the case for most other medical applications. The outstanding results achieved by deep learning techniques in developing such applications have improved the diagnostic accuracy. Nevertheless, the performance of these models is heavily dependent on the volume of labelled data used for training, which is unfortunately not available. To address this problem, traditional data augmentation is usually adopted. Recently, the emergence of a generative adversarial network (GAN) seems a more plausible solution, where synthetic images are generated. In this work, we have developed a deep generative adversarial network (DGAN) multi-class classifier, which can generate skin problem images by learning the true data distribution from the available images. Unlike the usual two-class classifier, we have developed a multi-class solution, and to address the class-imbalanced dataset, we have taken images from different datasets available online. One main challenge faced during our development is mainly to improve the stability of the DGAN model during the training phase. To analyse the performance of GAN, we have developed two CNN models in parallel based on the architecture of ResNet50 and VGG16 by augmenting the training datasets using the traditional rotation, flipping, and scaling methods. We have used both labelled and unlabelled data for testing to test the models. DGAN has outperformed the conventional data augmentation by achieving a performance of 91.1% for the unlabelled dataset and 92.3% for the labelled dataset. On the contrary, CNN models with data augmentation have achieved a performance of up to 70.8% for the unlabelled dataset. The outcome of our DGAN confirms the ability of the model to learn from unlabelled datasets and yet produce a good diagnosis result.


Assuntos
Processamento de Imagem Assistida por Computador , Redes Neurais de Computação , Processamento de Imagem Assistida por Computador/métodos
4.
PLoS One ; 16(8): e0256500, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34437623

RESUMO

The real cause of breast cancer is very challenging to determine and therefore early detection of the disease is necessary for reducing the death rate due to risks of breast cancer. Early detection of cancer boosts increasing the survival chance up to 8%. Primarily, breast images emanating from mammograms, X-Rays or MRI are analyzed by radiologists to detect abnormalities. However, even experienced radiologists face problems in identifying features like micro-calcifications, lumps and masses, leading to high false positive and high false negative. Recent advancement in image processing and deep learning create some hopes in devising more enhanced applications that can be used for the early detection of breast cancer. In this work, we have developed a Deep Convolutional Neural Network (CNN) to segment and classify the various types of breast abnormalities, such as calcifications, masses, asymmetry and carcinomas, unlike existing research work, which mainly classified the cancer into benign and malignant, leading to improved disease management. Firstly, a transfer learning was carried out on our dataset using the pre-trained model ResNet50. Along similar lines, we have developed an enhanced deep learning model, in which learning rate is considered as one of the most important attributes while training the neural network. The learning rate is set adaptively in our proposed model based on changes in error curves during the learning process involved. The proposed deep learning model has achieved a performance of 88% in the classification of these four types of breast cancer abnormalities such as, masses, calcifications, carcinomas and asymmetry mammograms.


Assuntos
Neoplasias da Mama/classificação , Neoplasias da Mama/patologia , Redes Neurais de Computação , Algoritmos , Neoplasias da Mama/diagnóstico por imagem , Feminino , Humanos , Reprodutibilidade dos Testes
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