Impact of research on maize production challenges in Hungary.

Maize (Zea mays L), as a major cereal crop produced in Hungary in addition to wheat, attracts enormous research from both educational and non-educational institutions. Research is aimed at addressing the key abiotic, biotic and social economic constraints. The stakeholders and institutions involved in research are spread all over Hungary. Currently, no review has been done to comprehensively reveal the trend of maize research in Hungary, as well as key players such as institutions, universities, industry and researchers. Hence, this bibliographic review was conducted to: i) identify the major research institutions and their contribution towards maize research in Hungary; ii) evaluate the major maize research areas in Hungary between 1975 and 2022. Literature search was conducted in Web of Science (WoS) database using keywords; 'maize' OR 'maize' + 'Research' + 'Hungary'. Bibliometric analyses were performed using the VOSviewer software. Changes in the publication trend of documents was tested using Mann Kendall Test. A total of 947 publications related to the topic were published by 441 institutions between 1975 and 2022. There was a significant (p = 0.001) positive increase in the number of published documents. Hungarian Academy of Science (210 documents) and University of Debrecen (132 documents) recorded the highest number of publications contributing 58.7% of the maize research literature in Hungary. The major research areas included: increasing maize yield, hybrid development, pests and diseases, irrigation, fertilization (nitrogen), drought, temperature, gene expression and climate change. The increasing number of published documents signifies an improved response to addressing maize production challenges through research in order to boost its productivity.

The effect of age and sex on carcass traits and body composition of Hungarian yearling farmed red deer (Cervus elaphus hippelaphus).

Carcass characteristics were studied in 80 young Hungarian red deer in different ages (12, 15, 18 and 20 months of age). In all age group 10 male and 10 female were slaughtered. The dressed carcass weight in skin varied between 53.72 and 65.66% of live weight. The first class lean meat varied between 14.3 and 16.6% of live weight. The live weight, carcass weight increased with the age and differed also between sexes. The highest dressing percentages were found at 20 months of age in both sexes (♂: 65.7%, ♀: 62.5%). Mainly the hinds had higher loin, leg and shoulder proportions of carcass at 20 months of age than the stags. The carcass muscle, bone and fat content were measured by computer tomography. These traits were grown and their proportion changed with the age. The bone to muscle ratio gradually decreased with the age while the fat to muscle ratio increased after 15 months of age (♂: from 0.13 to 0.17, ♀: from 0.15 to 0.18). At 18 month of age the hinds had higher bone to muscle and fat to muscle ratio than the stags'. The fat percentage of carcasses increased with the age in both sexes (♂: from 8.01% to 11.04%, ♀: from 8.40% to 11.28%). The hinds had higher values than the stags but it was significant just at 20 months of age. From the meat quality attributes there were found differences between ages in the case of pH, lightness, drip loss, cooking loss and shear force. The highest pH was found at 12 months of age in both sexes. There were found 5% intermediate pH (6.2 < pH < 5.8) at 12 and 15 months of age, all of them were male. The highest lightness values were observed at 18 months of age in both sexes (♂: 13.47, ♀: 14.90). There were differences between sexes in pH at all ages, except 15 months of age, and at 18 months of age in redness and lightness. Based on our results, the optimal slaughtering time for Hungarian red deer is 20 months of age, because this is when the dressing percentage is the best for both sexes. Meat quality traits changed with age, and gender differences sexes were the most pronounced for these traits at 18 months of age.

[The effect of surgical psychoeducation on the outcome of spinal surgery]. / A mutéti felkészítés hatásának vizsgálata gerincmutétet követoen.

Background and purpose – Interdiscipli­ nary researches demonstrate that patients’ fears and anxieties about surgery play a key role in the success of postoperative recovery. Psychoeducation is a professional information transfer method that aims to increase patients’ knowledge about their dis­ ease, and how to cope with it, and to emo­ tionally process the problems associated with the disease. If patients feel competent in their own healing process after surgery, they will experience less pain and become self­sufficient sooner, thereby the number of nursing days spent in the clinic reduces.
Methods – In this study the effect of psycho-education before spinal surgery on the use of postoperative analgetics was investigated. Results – The drug consumption of the study group who had been previously administered patient education is significantly reduced in comparison the control group.
Conclusion – Cooperation of a psychologist in surgical therapy promotes early recovery of patients in physical and mental well­being and reduces the costs of rehabilitation as well.

Parentage testing and looking for single nucleotide markers associated with antler quality in deer (Cervus elaphus).

To provide a cost-efficient parentage testing kit for red deer (Cervus elaphus), a 63 SNP set has been developed from a high-density Illumina BovineHD BeadChip containing 777 962 SNPs after filtering of genotypes of 50 stags. The successful genotyping rate was 38.6 % on the chip. The ratio of polymorphic loci among effectively genotyped loci was 6.5 %. The selected 63 SNPs have been applied to 960 animals to perform parentage control. Thirty SNPs out of the 63 had worked on the OpenArray platform. Their combined value of the probability of identity and exclusion probability was 4.9 × 10 - 11 and 0.99803, respectively. A search for loci linked with antler quality was also performed on the genotypes of the above-mentioned stags. Association studies revealed 14 SNPs associated with antler quality, where low-quality antlers with short and thin main beam antlers had values from 1 to 2, while high-quality antlers with long and strong main beams had values between 4 and 5. The chance for a stag to be correctly identified as having high-value antlers is expected to be over 88 %.

Nutrient Composition Analysis of Maize Hybrids Affected by Different Nitrogen Fertilisation Systems.

Maize is one of the most widely used plants in the agricultural industry, and the fields of application of this plant are broad. The experiment was conducted at the Látókép Crop Production Experimental Station of the University of Debrecen, Hungary. Three mid-ripening maize hybrids with different FAO numbers were used in the present study. The effects of different nitrogen supplies were examined as a variable rate of abiotic stress and the interrelationship among the essential nutrients through the nutrient acquisition and partitioning of the different vegetative and generative plant parts. The results showed that NPK application compared to the control treatment (no fertilizer application) increased DM in all tissues of maize, while increasing nitrogen application from 120 to 300 kg ha-1 had no significant effect on this trait. The highest protein content was obtained with the nitrogen application of 120 kg ha-1, and the higher nitrogen fertilizer application had no significant effect on this trait. Seeds and leaves had a maximum zinc and manganese value in terms of nitrogen content (protein). Dry matter was positively correlated with nitrogen, potassium, and manganese content, while the dry matter had a negative correlation with nickel content. In general, to achieve a maximum quantitative and qualitative yield, it is recommended to use NPK fertilizer with a rate of 120 kg ha-1 N for maize cultivation.

Analysis of Nutrient-Specific Response of Maize Hybrids in Relation to Leaf Area Index (LAI) and Remote Sensing.

Leaf area index (LAI) indicates the leaf area per ground surface area occupied by a crop. Various methods are used to measure LAI, which is unitless and varies according to species and environmental conditions. This experiment was carried out in three different nitrogen ranges (control, 120 kg N ha-1, and 300 kg N ha-1) + PK nutrient levels, with five replications used for leaf area measurement on seven different maize hybrids. Hybrids had different moisture, protein, oil, and starch contents. N (1, 2) + PK treatments had a desirable effect on protein, starch, and yield. P0217 LAI had a minimal response at these fertiliser levels. LAI for Sushi peaked at different dates between control and fertiliser treatments. This result showed that Sushi has an excellent capacity for LAI. LAI values on 15 June 2020 showed minimum average values for all hybrids, and it had a maximum average values on 23 July 2020. LAI had maximum performance between the average values treatments in Sushi, Armagnac, Loupiac, and DKC4792 on 15 June 2020. This study also provides insights for examining variably applied N doses using crop sensors and UAV remote-sensing platforms.

Recovery of Biophenols from Olive Vegetation Waters by Carbon Nanotubes.

In this work, the possibility of using carbon nanotubes for the treatment of olive vegetation waters (OVWs) was investigated. In general, the disposal of OVWs represents an important environmental problem. The possibility of considering these waters no longer just as a problem but as a source of noble substances, thanks to the recovery of biophenols from them, was tested. In particular, predetermined quantities of olive vegetation waters were treated with carbon nanotubes. The quantities of adsorbed biophenols were studied as a function of the quantities of carbon nanotubes used and the contact time. The experimental conditions for obtaining both the highest possible quantities of biophenol and a purer adsorbate with the highest percentage of biophenols were studied. After the adsorption tests, the vegetation waters were analyzed by UV spectrophotometry to determine, in particular, the variation in the concentration of biophenols. The carbon nanotubes were weighed before and after each adsorption test. In addition, kinetic studies of the adsorption processes were considered. Carbon nanotubes proved their effectiveness in recovering biophenols.

Comparison of Maize Genotypes Using Drought-Tolerance Indices and Graphical Analysis under Normal and Humidity Stress Conditions.

This study aimed to identify drought-tolerant genotypes and to evaluate and compare the response of genotypes under normal conditions and humidity stress. The experiment was conducted in a Randomized Complete Block Design (RCBD) on 12 commercial single cross hybrids of maize (Zea mays L.) with three replications in two separate experiments under normal and stress conditions. GT biplot was used to compare genotypes under normal conditions and humidity stress. Based on the polygon diagrams' graphical analysis, KSC206, KSC704, KSC705 and KSC706 genotypes were identified as desirable hybrids. The ranking diagram of genotypes based on ideal genotype also showed that the KSC704 genotype had high desirability in all evaluated traits in normal and stress conditions. TOL, MP, HARM, GMP, SSI and STI indices were used to identify drought-tolerant genotypes, and the genotypes were ranked based on this index. Based on this, KSC260, SC302 and KSC400 hybrids were selected as resistant hybrids. Based on the correlation analysis between drought-tolerance indices, a positive correlation was observed between MP, GMP, HARM and STI indices. Based on the analysis of the PCA on the indices, the first and second principal components were given the titles of grain yield tolerance component under humidity stress conditions and grain yield stability component under normal humidity conditions, respectively. KSC704 was superior to other hybrids in terms of grain yield under normal conditions and stress, and the KSC260 hybrid was identified as a tolerant hybrid in terms of all studied traits under drought stress.

Standardized data on the incidence and mortality of female and male breast cancers in Hungary between 2000 and 2016. / A noi és a férfiemlorák standardizált incidencia- és mortalitásadatai Magyarországon 2000 és 2016 között.

Összefoglaló. Bevezetés: A rákbetegségek incidencia- (gyakorisági) értékei világszerte, így Magyarországon is folyamatosan növekednek. Az emlorákok elofordulása és kórlefolyása a két nemben azonban sajátosan különbözik. Célkituzés: Célul tuztük ki, hogy megvizsgáljuk és értékeljük a noi és a férfiemlorák incidencia- és mortalitási (halálozási) adatait Magyarországon 2000 és 2016 között. Módszer: A Központi Statisztikai Hivatalból és a Nemzeti Rákregiszterbol származó adatok standardizált, 100 000 fore számított feldolgozása. Eredmények: Magyarországon a vizsgált idoszakban az emlorákok gyakoriságának növekedése megközelítoleg ugyanolyan mértéku (39%) volt, mint az összes ráké (34%). Az emelkedés jelentos: a 2016-ban 8,7% részarányú noi emlorák esetében 39%, a 0,22%-os részarányú férfiráknál 60%. Ezzel szemben a halálozási adatok jelentos mértéku csökkenéseket mutatnak mind az összes daganat, mind a noi emlorák vonatkozásában, míg a férfiemlorák esetében a csökkenés nagyobb mértéku. A rosszindulatú daganatok incidenciája és a 2-es típusú diabetes mellitus (2DM) prevalenciája egyaránt magasan szignifikáns korrelációt mutatott az egy fore jutó bruttó nemzeti össztermék (GDP) értékének növekedésével. Új megfigyelés, hogy a 2DM-növekedés idoben megelozte a daganatok incidenciájának növekedését. Következtetés: A vizsgált idoszakban a noi és a férfiemlorákok magyarországi gyakorisági és halálozási adatai a nemzetköziekhez hasonló tendenciákat mutatnak. A férfiemlorákok sokkal ritkábbak, de kezelésük kevésbé hatékony. Új szempont, hogy a rosszindulatú daganatok gyakoribb megjelenésében a klinikailag kedvezotlenebb 2DM százalékos arányának (prevalenciájának) emelkedése is jelentos tényezo lehet az elhízáshoz kapcsolódva. A GDP növekedése kedvezoen hathatott a halálozások csökkenésében a kedvezobb gyógyítási és megelozési feltételek megteremtésével. Ugyanakkor ennek a növekedésnek szerepe lehet az elhízással összefüggo 2DM prevalenciájának emelkedésében is. Orv Hetil. 2022; 163(5): 181-186. INTRODUCTION: The incidence of malignant cancers is continuously growing. In breast cancers, the incidence and clinical course are greatly different in the two genders. OBJECTIVE: We aimed to investigate the incidence and mortality of breast cancers in females and males in Hungary between 2000 and 2016. METHODS: The data derived from the Hungarian Central Statistical Office and the National Cancer Registry were evaluated and standardized for 100 000 inhabitants. RESULTS: In Hungary, the elevation of breast cancer incidence (39%) showed a similar extent as that of total tumours (34%). In female breast cancers representing a much greater percent (8.7% in 2016) than that in males (0.22%), the increase was significant (39%) as in males (60 %). On the other hand, mortality was significantly lower for both of them regarding total malignant and female breast tumours, whereas the decrease was greater in the male breast cancers. The increase of GDP per capita showed highly significant correlation with the incidence of malignant tumours and prevalence of diabetes mellitus type 2 (2DM). It was a new finding that the increase in the prevalence of 2DM precedes the elevation of the incidence of cancer. CONCLUSION: In Hungary, the data of incidence and mortality of female and male breast cancers showed similar tendencies as the international ones. The breast cancers of males were rarer but their treatment was less effective. However, it was a new aspect that in the increased incidence of malignant tumours also the greater prevalence of 2DM could be an important factor related to obesity. Orv Hetil. 2022; 163(5): 181-186.

Genotype by Trait Interaction (GT) in Maize Hybrids on Complete Fertilizer.

We investigated the interaction between genotype by trait, and an experiment was conducted at the University of Debrecen. Two maize cultivars, FAO340 and FAO410, were studied in a randomized complete block design with four replications. This experiment was applied to the six fertilization treatments. Fertilizer levels were NPK0 (control) (N:0, P2O5:0, K2O:0), NPK1 (N:30, P2O5:23, K2O:27), NPK2 (N:60, P2O5:46, K2O:54), NPK3 (N:90, P2O5:69, K2O:81), NPK4 (N:120, P2O5:92, K2O:108), and NPK5 (N:150, P2O5:115, K2O:135). The first principal component showed 54.24%, and the second principal component showed 20.75%, which explained the total squares interaction using the AMMI model in the case of the FAO410 hybrid. As regards the FAO340 hybrid, the first principal component showed 58.18%, and the second principal component showed 18.04%, explaining the total squares interaction using the AMMI model in the FAO410 hybrid. In the GGE biplot on FAO410, the first and the second principal components covered 91.20% of the total data in this analysis. Accordingly, the desirable treatment was NPK5, followed by NPK4, NPK2, NPK3, NPK1, and NPK0. NPK4 and NPK5 had the most desirable treatments for the number of seeds per row, chlorophyll, weight of 1000 seeds, and stem diameter in the case of the FAO410 hybrid.

The Role of Carbon Nanotube Pretreatments in the Adsorption of Benzoic Acid.

Four different types of multi-walled carbon nanotubes (MWCNTs) were used and compared for the treatment of benzoic acid contaminated water. The types of nanotubes used were: (1) non-purified (CNTsUP), as made; (2) purified (CNTsP), not containing the catalyst; (3) oxidized (CNTsOX), characterized by the presence of groups such as, -COOH; (4) calcined (CNTs900), with elimination of interactions between nanotubes. In addition, activated carbon was also used to allow for later comparison. The adsorption tests were conducted on an aqueous solution of benzoic acid at concentration of 20 mg/L, as a model of carboxylated aromatic compounds. After the adsorption tests, the residual benzoic acid concentrations were measured by UV-visible spectrometry, while the carbon nanotubes were characterized by TG and DTA thermal analyses and electron microscopy (SEM). The results show that the type of nanotubes thermally treated at 900 °C has the best performances in terms of adsorption rate and amounts of collected acid, even if compared with the performance of activated carbons.

Yield Stability Analysis of Maize (Zea mays L.) Hybrids Using Parametric and AMMI Methods.

The present study investigated the stability and adaptability of maize (Zea mays L.) hybrids. In this study, 12 maize hybrids were planted and examined considering the grain yield. The experiment was arranged in a randomized complete block design (RCBD) with three replications in four research stations in Iran during two crop years. The combined analysis of variance showed that genotype-environment interactions were significant at one percent probability level. The grain yield can stabilize, and hybrids with specific adaptability are recommended to each environment. Hybrids with specific adaptability can be recommended to all types of the environment. Means comparison yield of the genotypes identified DC370 as a high-yield genotype. Regarding AMMI analysis, genotype × environment interactions (GEIs) and two first components were found significant. The SC647 genotype was identified as the most stable genotype. Regarding the stability parameters, SC647 and KSC705 genotypes were selected as the most stable genotypes. From AMMI1 and AMMI2 graphs, the SC647 genotype was identified as the most stable genotype compared with other hybrids.

How to characterize a strain? Clonal heterogeneity in industrial Saccharomyces influences both phenotypes and heterogeneity in phenotypes.

Populations of microbes are constantly evolving heterogeneity that selection acts upon, yet heterogeneity is nontrivial to assess methodologically. The necessary practice of isolating single-cell colonies and thus subclone lineages for establishing, transferring, and using a strain results in single-cell bottlenecks with a generally neglected effect on the characteristics of the strain itself. Here, we present evidence that various subclone lineages for industrial yeasts sequenced for recent genomic studies show considerable differences, ranging from loss of heterozygosity to aneuploidies. Subsequently, we assessed whether phenotypic heterogeneity is also observable in industrial yeast, by individually testing subclone lineages obtained from products. Phenotyping of industrial yeast samples and their newly isolated subclones showed that single-cell bottlenecks during isolation can indeed considerably influence the observable phenotype. Next, we decoupled fitness distributions on the level of individual cells from clonal interference by plating single-cell colonies and quantifying colony area distributions. We describe and apply an approach using statistical modeling to compare the heterogeneity in phenotypes across samples and subclone lineages. One strain was further used to show how individual subclonal lineages are remarkably different not just in phenotype but also in the level of heterogeneity in phenotype. With these observations, we call attention to the fact that choosing an initial clonal lineage from an industrial yeast strain may vastly influence downstream performances and observations on karyotype, on phenotype, and also on heterogeneity.

Treatment of Water Contaminated with Reactive Black-5 Dye by Carbon Nanotubes.

Most of the dyes used today by the textile industry are of synthetic origin. These substances, many of which are highly toxic, are in many cases not adequately filtered during the processing stages, ending up in groundwater and water courses. The aim of this work was to optimize the adsorption process of carbon nanotubes to remove an azo-dye, called Reactive Black-5, from aqueous systems. Particular systems containing carbon nanotubes and dye solutions were analyzed. Furthermore, the reversibility of the process and the presence of possible degradation phenomena by the dye molecules were investigated. For this purpose, the influence of different parameters on the adsorption process, such as the nature of the carbon nanotubes (purified and nonpurified), initial concentration of the dye, stirring speed, and contact times, were studied. The solid and liquid phases after the tests were characterized by chemical-physical techniques such as thermogravimetric analysis (TG, DTA), UV spectrophotometry, BET (Brunauer, Emmett, Teller), and TOC (total organic carbon) analysis. The data obtained showed a high adsorbing capacity of carbon nanotubes in the removal of the Reactive Black-5 dye from aqueous systems. Furthermore, the efficiency of the adsorption process was observed to be influenced by the stirring speed of the samples and the contact time, while purified and nonpurified nanotubes provided substantially the same results.

Correlation between the Expression of Angiogenic Factors and Stem Cell Markers in Human Uveal Melanoma.

Uveal melanoma (UM) is the most common malignant tumor of the eye with extremely high metastatic potential. UM tumor cells can disseminate only hematogenously, thus, angiogenic signals have a particular role in the prognosis of the disease. Although the presence of cancer stem cells (CSCs) in densely vascularized UMs has been reported previously, their role in the process of hematogenous spread of UM has not been studied. In this study, we investigated the regulation of angiogenesis in UM in correlation with the presence of CSCs. Seventy UM samples were collected to analyze the expression of CSC markers and angiogenic factors. The expression of CSC markers was studied by RT-PCR, Western blotting techniques and IHC-TMA technique. RT-PCR showed high expression of CSC markers, particularly nestin, FZD6 and SOX10 and somewhat lower expression of NGFR. The protein expression of FZD6, HIF-1α and VEGFA was further evaluated in 52 UM samples by the IHC-TMA technique. We report here for the first time a significant correlation between FZD6 and VEGFA expression in UM samples. The observed correlation between FZD6 and VEGFA suggests the presence of CSCs in UM that are associated with the vascularization process.

Mining the red deer genome (CerEla1.0) to develop X-and Y-chromosome-linked STR markers.

Microsatellites are widely applied in population and forensic genetics, wildlife studies and parentage testing in animal breeding, among others, and recently, high-throughput sequencing technologies have greatly facilitated the identification of microsatellite markers. In this study the genomic data of Cervus elaphus (CerEla1.0) was exploited, in order to identify microsatellite loci along the red deer genome and for designing the cognate primers. The bioinformatics pipeline identified 982,433 microsatellite motifs genome-wide, assorted along the chromosomes, from which 45,711 loci mapped to the X- and 1096 to the Y-chromosome. Primers were successfully designed for 170,873 loci, and validated with an independently developed autosomal tetranucleotide STR set. Ten X- and five Y-chromosome-linked microsatellites were selected and tested by two multiplex PCR setups on genomic DNA samples of 123 red deer stags. The average number of alleles per locus was 3.3, and the average gene diversity value of the markers was 0.270. The overall observed and expected heterozygosities were 0.755 and 0.832, respectively. Polymorphic Information Content (PIC) ranged between 0.469 and 0.909 per locus with a mean value of 0.813. Using the X- and Y-chromosome linked markers 19 different Y-chromosome and 72 X-chromosome lines were identified. Both the X- and the Y-haplotypes split to two distinct clades each. The Y-chromosome clades correlated strongly with the geographic origin of the haplotypes of the samples. Segregation and admixture of subpopulations were demonstrated by the use of the combination of nine autosomal and 16 sex chromosomal STRs concerning southwestern and northeastern Hungary. In conclusion, the approach demonstrated here is a very efficient method for developing microsatellite markers for species with available genomic sequence data, as well as for their use in individual identifications and in population genetics studies.

Analysis of Low Cancer Mortality Rates in the Wine Regions of Tokaj and Balaton in Hungary.

The age-adjusted death rates (AADRs) due to cancers were investigated in two historical regions of white wines (Tokaj and Balaton) and in Hódmezovásárhely (HMV) as a control territory in Hungary between 2000 and 2010 evaluating 111,910 persons. The results of AADRs due to the eight most frequent types/gastrointestinal cancers were as follows: Tokaj 2120/664, Balaton: 2417/824, HMV: 2770/821, nationwide: 2773/887. The values found in Tokaj and Balaton regions were significantly less than those of HMV and nationwide. However, the least values were found in Tokaj. This Tokaj-related strong difference was not found among the regions in the case of young populations with hematological diseases but only in the older people who have been consuming their wines for decades. Supposedly, this wine-specific anti-cancer phenomenon could be related to the chemical differences existing in the two types of white wines, namely, to the pro-oxidant molecules of Tokaj wines derived from Botrytis cinerea. The roles of red meat consumption, hardness of drinking water, mineral content of soil, and socioeconomic status were negligible. It should be stressed that these data are valid only for these populations, for this period. Noteworthily, the different types of wines may have different effects on mortality rates during long-lasting consumptions.

Adsorption of Reactive Blue 116 Dye and Reactive Yellow 81 Dye from Aqueous Solutions by Multi-Walled Carbon Nanotubes.

The multi-walled carbon nanotubes obtained by catalytic chemical vapour deposition synthesis are used as a solid matrix for the adsorption of the Reactive Blue 116 dye and the Reactive Yellow 81 dye from aqueous solutions at different pH values. The batch tests carried out allowed us to investigate the different effects of pH (2, 4, 7, 9 and 12) and of the contact time (2.5 ÷ 240 min) used. The liquid phase was analysed using ultraviolet-visible spectrophotometry in order to characterise the adsorption kinetics, the transport mechanisms and the adsorption isotherms. The adsorption of the optimal dye was observed at pH 2 and 12. The pseudo-first order kinetic model provided the best approximation of experimental data compared to the pseudo-second order kinetic model. The predominant transport mechanism investigated with the Weber and Morris method was molecular diffusion for both Reactive Yellow 81 and Reactive Blue 116, and the equilibrium data were better adapted to the Langmuir isothermal model. The maximum adsorption capacity for Reactive Yellow 81 and Reactive Blue 116 occurred with values of 33.859 mg g-1 and 32.968 mg g-1, respectively.

Surgery formulae for the Seiberg-Witten invariant of plumbed 3-manifolds.

Assume that M ( T ) is a rational homology sphere plumbed 3-manifold associated with a connected negative definite graph T . We consider the combinatorial multivariable Poincaré series associated with T and its counting functions, which encode rich topological information. Using the 'periodic constant' of the series (with reduced variables associated with an arbitrary subset I of the set of vertices) we prove surgery formulae for the normalized Seiberg-Witten invariants: the periodic constant associated with I appears as the difference of the Seiberg-Witten invariants of M ( T ) and M ( T \ I ) for any I .

Prognosis and Treatment Outcomes of Patients Undergoing Resection of Brain Metastases from Breast Cancer.

BACKGROUND: Brain metastases from breast cancer have poor prognosis and are a challenge to treat. Multiple treatment options are available. Descriptive and prognostic data on breast cancer brain metastases is limited. PATIENTS AND METHODS: This study analyzed clinical data of patients who underwent surgical resection of one or more brain metastases. Histological and clinical characteristics, as well as treatment modalities, were analyzed. RESULTS: Initial tumor stage or grade was found not to correlate with the median time to developing brain metastases or survival. Human epidermal growth factor receptor 2 (HER2)-positive status was not associated with shorter median time to developing brain metastases. No correlation was found between the number of brain metastases and patient outcome. Results confirm the survival benefit of surgical resection with or without irradiation. CONCLUSION: Data showed that patients with HER2-positive and those with triple-negative breast cancer develop brain metastases at lower stages but not earlier after diagnosis, and survival is mostly dependent on treatment modality rather than histological subtype.