1.
Chem Commun (Camb)
; 51(15): 3266-9, 2015 Feb 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25616078
RESUMO
We report a novel strategy to enzymatically release affinity-selected cells, such as circulating tumor cells (CTCs), from surfaces with high efficiency (â¼90%) while maintaining cell viability (>85%). The strategy utilizes single-stranded DNAs that link a capture antibody to the surfaces of a CTC selection device. The DNA linkers contain a uracil residue that can be cleaved.