1.
Org Lett
; 25(12): 2108-2112, 2023 Mar 31.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36940090
RESUMO
The Pd/PMe3-catalyzed allylation of 1-(cyanomethyl)naphthalenes with allyl acetates proved to be para- rather than α-regioselective. This reaction is thought to proceed through ligand attack of the para-carbon in the arenes, electronically enriched by a cyano-stabilized α-carbanion, to the (π-allyl)palladium and a 1,5-hydrogen shift of the para-hydrogen from the dearomatized intermediate.