Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 8 de 8
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
2.
PLoS One ; 19(6): e0305869, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38913676

RESUMO

BACKGROUND: This study aimed to measure the preferences for mental health support among health professionals, their willingness to support the mental health of colleagues and associated factors. METHOD: A descriptive cross-sectional study was performed from August to October 2022 within five hospitals located in Hanoi, Vietnam. A total of 244 health professionals participated in the study. Data on socio-economic status, health and COVID-19-related characteristics, Depression Anxiety Stress Scale (DASS-21); and preferences for mental health support services were collected by using a structured self-reported questionnaire. Multivariate logistic regression models were utilized to identify associated factors with the demand for mental support services. RESULTS: 13.9%, 17.1% and 8.6% reported having at least mild depression, anxiety and stress, respectively. There 13.9% did not seek any mental health support during the COVID-19 pandemic. The most common support included talking with friends (52.9%), family (50.8%), colleagues (47.6%) and using social networks/Internet (43.5%). There 31.1% had been aware of mental health services, but only 18.0% used this service at least once. Regarding preferences, 47.3% had a demand for mental support services, and the most preferred service was providing coping skills (25.9%), followed by skills to support others against mental problems (22.2%). Major sources of support included psychiatrists (34.4%), colleagues (29.1%) and family (27.9%). The main preferred channels for support included telephone/mobile phone (35.7%) and Internet (20.9%). Only 12.3% were willing to provide mental support for colleagues during the pandemic. Age, education, perceived mental health status, ever seeking any mental service, and DASS-21 depression score were associated with demand for mental support services. CONCLUSION: This study found a lack of awareness of mental health services for health professionals, as well as moderate levels of demand for this service in this population. Raising awareness and developing tailored mental health support services are important to enhancing the mental well-being of health professionals in Vietnam to prepare for the next pandemic.


Assuntos
COVID-19 , Depressão , Pessoal de Saúde , Serviços de Saúde Mental , Saúde Mental , Humanos , COVID-19/epidemiologia , COVID-19/psicologia , Vietnã/epidemiologia , Masculino , Feminino , Adulto , Estudos Transversais , Pessoal de Saúde/psicologia , Pessoa de Meia-Idade , Depressão/epidemiologia , Ansiedade/epidemiologia , Pandemias , Inquéritos e Questionários , SARS-CoV-2 , Estresse Psicológico/epidemiologia , Apoio Social
3.
Biochem Biophys Res Commun ; 719: 150043, 2024 Jul 30.
Artigo em Inglês | MEDLINE | ID: mdl-38735206

RESUMO

In this study, a simple green synthesis of vanadium pentoxide nanoparticles (VNPs) was prepared by the extract of Kaffir lime fruit (Citrus hystrix) as a green reducing and stabilizing agent, along with the investigation of calcination temperature was carried out at 450 and 550 °C. It was affirmed that, at higher temperature (550 °C), the VNPs possessed a high degree crystalline following the construction of (001) lattice diffraction within an increase in crystalline size from 47.12 to 53.51 nm, although the band gap of the materials at 450 °C was lower than that of the VNPs-550 (2.53 versus 2.66 eV, respectively). Besides, the materials were assessed for the potential bioactivities toward antibacterial, antifungal, DNA cleavage, anti-inflammatory, and hemolytic performances. As a result, the antibacterial activity, with minimal inhalation concentration (MIC) < 6.25 µg/mL for both strains, and fungicidal one of the materials depicted the dose-dependent effects. Once, both VNPs exhibited the noticeable efficacy of the DNA microbial damage, meanwhile, the outstanding anti-inflammatory agent was involved with the IC50 of 123.636 and 227.706 µg/mL, accounting for VNPs-450 and VNPs-550, respectively. Furthermore, this study also demonstrated the hemolytic potential of the VNPs materials. These consequences declare the prospects of the VNPs as the smart and alternative material from the green procedure in biomedicine.


Assuntos
Antibacterianos , Citrus , Frutas , Extratos Vegetais , Compostos de Vanádio , Citrus/química , Extratos Vegetais/química , Extratos Vegetais/farmacologia , Compostos de Vanádio/química , Compostos de Vanádio/farmacologia , Frutas/química , Antibacterianos/farmacologia , Antibacterianos/química , Antibacterianos/síntese química , Nanopartículas/química , Testes de Sensibilidade Microbiana , Anti-Inflamatórios/farmacologia , Anti-Inflamatórios/química , Antifúngicos/farmacologia , Antifúngicos/química , Antifúngicos/síntese química , Temperatura , Hemólise/efeitos dos fármacos , Química Verde , Humanos
4.
Int J Biol Macromol ; 268(Pt 2): 131760, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38663693

RESUMO

In the adsorption process for wastewater treatment, the adsorbent plays an important role. A composite adsorptive material composed of graphitic carbon nitride and agar-derived porous carbon (CNPC) was fabricated from simple precursors (melamine, thiourea, and agar) and through a facile procedure with different melamine and thiourea ratios. Characterization of CNPC proved a successful formation of a porous structure consisting of mesopores and macropores, wherein CNPC holds distinctive electrochemical (lowered resistance and higher specific capacity) and photochemical properties (lowered bandgap to 2.33 eV) thanks to the combination of graphitic carbon nitride (CN) and agar-derived porous carbon (PC). Inheriting the immanent nature, CNPC was subjected to the adsorption of methylene blue (MB) dye in an aqueous solution. The highest adsorption capacity was 133 mg/g for CNPC-4 which was prepared using a melamine to thiourea ratio of 4:4 - equivalent to the removal rate of 53.2 % and following the pseudo-I-order reaction rate. The effect of pH points out that pH 7 and 9 were susceptible to maximum removal and pretreatment is not required while the optimal ratio of 7.5 mg of MB and 30 mg of material was also determined to yield the highest performance. Furthermore, the reusability of the material for three consecutive cycles was evaluated based on two methods pyrolysis at 200 °C and photocatalytic degradation by irradiation under visible light. In general, the photocatalytic regeneration pathway is more ample and efficient than pyrolysis in terms of energy efficiency (saving energy over 10 times) and adsorption capacity stability. As a whole, the construction of accessible regenerative and stable adsorbent could be a venturing step into the sustainable development spearhead for industries.


Assuntos
Ágar , Grafite , Azul de Metileno , Poluentes Químicos da Água , Adsorção , Grafite/química , Porosidade , Poluentes Químicos da Água/química , Poluentes Químicos da Água/isolamento & purificação , Azul de Metileno/química , Ágar/química , Purificação da Água/métodos , Triazinas/química , Recuperação e Remediação Ambiental/métodos , Carbono/química , Águas Residuárias/química , Concentração de Íons de Hidrogênio , Compostos de Nitrogênio/química , Cinética , Tioureia/química
5.
Environ Sci Pollut Res Int ; 30(33): 81206-81225, 2023 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-37314558

RESUMO

In this study, zinc oxide-titanium dioxide/graphene aerogel (ZnO-TiO2/GA) was successfully synthesized through a simple and cost-effective hydrothermal self-assembly process. Besides, the surface response model and the experimental design according to the Box-Behnken model were selected to determine the optimal removal efficiency for crystal violet (CV) dye and para-nitrophenol (p-NP) phenolic compound. According to the obtained results, the highest degradation efficiency for CV dye of 99.6% was obtained under the following conditions: pH 6.7, CV concentration of 23.0 mg/L, and catalyst dose of 0.30 g/L. For p-NP, the degradation efficiency reached 99.1% under the following conditions: H2O2 volume of 1.25 mL, pH 6.8, and catalyst dose of 0.35 g/L. Therewithal, kinetic models of adsorption-photodegradation, thermodynamic adsorption, and free radical scavenging experiments were also investigated to propose the specific mechanisms involving the removal of CV dye and p-NP. According to the aforementioned results, the study provided a resulting ternary nanocomposite with great removal performance for water pollutants via the synergetic effects of adsorption and photodegradation processes.


Assuntos
Grafite , Óxido de Zinco , Óxido de Zinco/química , Grafite/química , Porosidade , Peróxido de Hidrogênio , Fotólise , Catálise , Titânio/química , Adsorção
6.
Int J Biol Macromol ; 242(Pt 2): 124607, 2023 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-37116839

RESUMO

In this study, silver-immobilized graphene oxide/chitosan (AGC/CTS) membranes were assembled by the solvent evaporation method, wherein Curcuma longa extract was used to synthesize silver-immobilized graphene oxide (AGC) nanocomposite. The characterization results showed that the AGC was successfully synthesized with AgNPs distributed quite evenly on GO sheets. The as-prepared AGC also exhibited high antibacterial activity and low cytotoxicity towards normal cell lines compared to human epithelial carcinoma cell lines. Besides, the fabrication of AGC/CTS membranes was additionally assessed with different AGC ratios and thicknesses. The results revealed the membrane containing 3 wt% of AGC with great hygroscopicity and elastic modulus of 27.03 ± 3.07 MPa. The samples also performed excellent bactericidal capability, along with good mechanical properties for banana preservation. Therewithal, the membrane-coated bananas were also elucidated to ripen at slower paces and less damage, with no appearance of patches of mold on the banana peel surface, eventually prolonging the shelf life of bananas up to 10 days as compared to the non-coated ones. The aforesaid results confirm the potential application of the AGC/CTS membrane as a safe and alternative fruit preservation agent in the food industry.


Assuntos
Quitosana , Grafite , Nanopartículas Metálicas , Musa , Nanocompostos , Humanos , Prata/química , Grafite/química , Nanocompostos/química , Nanopartículas Metálicas/química , Antibacterianos/farmacologia , Antibacterianos/química
7.
Int J Biol Macromol ; 220: 348-359, 2022 Nov 01.
Artigo em Inglês | MEDLINE | ID: mdl-35981679

RESUMO

In this study, selenium microparticles (SeMPs) were green-synthesized by utilizing the Terminalia catappa leaves extract as an effective reducing agent. SeMPs were then decorated onto graphene oxide (GO) with the assistance of ultrasound using the ex-situ technique to obtain the SeMPs-GO composite. SeMPs and SeMPs-GO were thoroughly characterized with modern analytical methods, whereas the antibacterial performance of the composites was evaluated via the optical density method. Particularly, SeMPs-GO held up an inhibition of 99 % against both Gram-positive and Gram-negative bacteria strains as well as restrained 50 % of fungal activity. SeMPs-GO was additionally incorporated onto chitosan (CTS) to collect the SeMPs-GO/CTS membrane which was characterized by similar advanced analysis methods. The antibacterial property of the membrane was determined by the inhibition zone diameter. Furthermore, the membrane exhibited good thermal and mechanical characteristics, showing no sign of degradation at a temperature below 260 °C, and a tensile strength of 38 N/mm2. The swelling degree reached 148 % after 6 h of immersion in water, which was stable after 72 h (153 %). The obtained membrane can potentially be utilized for medical and food applications.


Assuntos
Quitosana , Grafite , Selênio , Antibacterianos/farmacologia , Bactérias Gram-Negativas , Bactérias Gram-Positivas , Grafite/farmacologia , Óxidos , Extratos Vegetais/farmacologia , Substâncias Redutoras , Água
8.
Asia Pac Allergy ; 11(1): e9, 2021 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-33604279

RESUMO

BACKGROUND: Stepping down treatment for well-controlled mild asthma is challenging to clinicians. The step-down strategy using regularly-intermittent low-dose inhaled corticosteroid has been applied at the University Medical Center (UMC) of Ho Chi Minh City, called as "UMC" approach. OBJECTIVE: This study aimed to evaluate the efficiency of UMC step-down strategy in well- controlled mild asthma. METHODS: A real-world retrospective descriptive study was conducted at UMC from 2009 to 2018. All asthmatic patients (age ≥ 12) who received step-down therapy using this UMC approach were evaluated. RESULTS: Among 2,072 asthma patients to be treated with UMC step-down strategy, only 112 subjects were eligible. The median age was 38.5 years and female was 62.5%. Most patients at their initial presentation were indicated step 4 treatment (87.5%). The controller medications before initiation of UMC treatment included fluticasone propionate 125 µg once-daily, salmeterol/fluticasone propionate 25/125 µg once-daily, and formoterol/budesonide 4.5/160 µg once-daily. After being treated with the UMC approach, the rates of well-controlled asthma ranged from 67.6% to 91.1%. During 1 year with UMC treatment, pulmonary function remained stable and only 7 subjects (6.3%) developed exacerbation. CONCLUSION: The UMC step-down treatment for well-controlled mild asthma was relatively efficient in maintaining asthma control, stabilization of pulmonary function, and reducing risk of severe exacerbation.

SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...